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S

Stuart W. Hughes

pathios therapeutics limited

35H指数
70论文数
5.5K被引数
收录论文 20
发表时间
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Low pH, High Stakes: A Narrative Review Exploring the Acid-Sensing GPR65 Pathway as a Novel Approach in Renal Cell CarcinomaGrant, M.; Cipriani, B.; Corbin, A.; Miller, D.; Naylor, A.; Hughes, S.; McCarthy, T.; Ambarkhane, S.; Memon, D.; Millward, M.; 等. 低pH，高风险：一项探讨GPR65通路作为肾细胞癌新型治疗策略的叙事性综述。Cancers 2025, 17, 3883. [Google Scholar] [CrossRef] [PubMed]
errCancers
IF4.4
err2026-03-04
err0
errOAAI
errMichael Grant; Barbara Cipriani; Alastair Corbin; David Miller; Alan Naylor; Stuart Hughes; Tom McCarthy; Sumeet Ambarkhane; Danish Memon; Michael Millward; Sumanta Pal; Ignacio Melero
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Correction: Grant et al. Low pH, High Stakes: A Narrative Review Exploring the Acid-Sensing GPR65 Pathway as a Novel Approach in Renal Cell Carcinoma. Cancers 2025, 17, 3883更正：Grant等人，《低pH，高风险：探索酸感受GPR65通路作为肾细胞癌新方法的叙事综述》。《Cancers》2025年第17卷，第3883页。
errCancers
IF4.4
err2026-02-27
err0
errOAAI
errMichael Grant; Barbara Cipriani; Alastair Corbin; David Miller; Alan Naylor; Stuart Hughes; Tom McCarthy; Sumeet Ambarkhane; Danish Memon; Michael Millward; Sumanta Pal; Ignacio Melero
err分享
err收藏
Validation of GPR35 as a novel cancer target in digestive tract cancers and discovery of potent, selective GPR35 inverse agonists
errCANCER RESEARCH
IF16.6
err2023-04-04
err0
PREAI
errWestcott, James; Luckhurst, Christopher A.; McKenzie, Grahame; Memon, Danish; Lin, Li-Chiung; Knight, Sinead; Blaikley, Elizabeth J.; Pearce, Martin; Warren, Hannah R.; Parker, Eleanor; Milligan, Graeme; Hughes, Stuart W.; McCarthy, Tom
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The translational biology of small molecule GPR65 inhibitors: shared effects between mouse models and human primary tumors highlight the unique transformative potential of targeting a genetically validated innate immune checkpoint
errCANCER RESEARCH
IF16.6
err2023-04-04
err1
PREAI
errCipriani, Barbara; Corbin, Alastair; Miller, David; Naylor, Alan; Khan, Faraz; Milne, Gavin; Young, Barbara; Satchell, Rupert; Sarkar, Sourav; Quareshy, Mussa; Nika, Anastasia; Singh, Preeti; Knox, Gavin; Turner, Darryl; Sankaran, Satish; Basak, Nandini Pal; Bohn, Toszka; Bopp, Tobia; Koturan, Surya; Sun, Bo; Fairfax, Benjamin; McCarthy, Tom; Hughes, Stuart
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Measurement and State-Dependent Modulation of Hypoglossal Motor Excitability and Responsivity In-Vivo
errSCIENTIFIC REPORTS
IF3.9
err2020-01-17
err7
errOAAI
errAggarwal, Jasmin A.; Liu, Wen-Ying; Montandon, Gaspard; Liu, Hattie; Hughes, Stuart W.; Horner, Richard L.
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Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity
errNATURE REVIEWS NEUROSCIENCE
IF26.7
err2018-01-11
err90
errOAAI
errCrunelli, Vincenzo; Lorincz, Magor L.; Connelly, William M.; David, Francois; Hughes, Stuart W.; Lambert, Regis C.; Leresche, Nathalie; Errington, Adam C.
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Defining optimal dose schedules for ATR inhibitors in combination with DNA damaging drugs: Informing clinical studies of VX-970, the first in -class ATR inhibitor
errCANCER RESEARCH
IF16.6
err2016-07-15
err8
PREAI
errPollard, John; Reaper, Phil; Peek, Adele; Hughes, Stuart; Gladwell, Scott; Jones, Julie; Chiu, Peter; Wood, Mark; Tolman, Crystal; Mac Johnson; Littlewood, Peter; Penney, Marina; McDermott, Katherine; Hare, Brian; Fields, Scott Z.; Asmal, Mohammed; O'Carrigan, Brent; Yap, Timothy A.
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Pre -clinical combinations of ATR and PARP inhibitors: Defining target patient populations and dose schedule
errCANCER RESEARCH
IF16.6
err2016-07-15
err5
PREAI
errPollard, John; Reaper, Phil; Peek, Adele; Hughes, Stuart; Djeha, Hakim; Cummings, Steven; Larbi, Karen; Penney, Marina; Sullivan, Jim; Takemoto, Darin; DeFranco, Chris
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VX-970, the first-in-class inhibitor of the DNA damage repair enzyme ATR
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errPollard, John; Reaper, Philip; Jones, Julie; Barnes, Christopher; Gladwell, Scott; Hughes, Stuart; Peak, Adele; Djeha, Hakim; Hall, Amy; Newsome, David; Wang, Yuxin; Boucher, Diane; Eustace, Brenda; Gu, Yong; Hare, Brian; Johnson, Mac; Milton, Sean; Murphy, Cheryl; Takemoto, Darin; Tolman, Crystal; Wood, Mark; Furey, Brinley; Penney, Marina; Li, Howard; Defranco, Christopher; Asmal, Mohammed; Fields, Scott
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State-dependent and reflex drives to the upper airway: basic physiology with clinical implications
errJOURNAL OF APPLIED PHYSIOLOGY
IF3.3
err2014-02-01
err65
errOAAI
errHorner, Richard L.; Hughes, Stuart W.; Malhotra, Atul
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Identification of a Pharmacological Target for Genioglossus Reactivation throughout Sleep
errSLEEP
IF4.9
err2014-01-01
err58
errOAAI
errGrace, Kevin P.; Hughes, Stuart W.; Horner, Richard L.
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Identification of the Mechanism Mediating Genioglossus Muscle Suppression in REM Sleep
errAMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
IF19.4
err2013-02-01
err176
PREAI
errGrace, Kevin P.; Hughes, Stuart W.; Horner, Richard L.
err分享
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The thalamic low-threshold Ca2+ potential: a key determinant of the local and global dynamics of the slow (<1 Hz) sleep oscillation in thalamocortical networks
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
IF3.7
err2011-10-13
err20
errOAAI
errCrunelli, Vincenzo; Errington, Adam C.; Hughes, Stuart W.; Toth, Tibor I.
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Temporal Framing of Thalamic Relay-Mode Firing by Phasic Inhibition during the Alpha Rhythm
errNEURON
IF15
err2009-09-01
err263
errOAAI
errLoerincz, Magor L.; Kekesi, Katalin A.; Juhasz, Gabor; Crunelli, Vincenzo; Hughes, Stuart W.
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Are corticothalamic 'up' states fragments of wakefulness?
errTRENDS IN NEUROSCIENCES
IF15.1
err2007-07-01
err273
errOAAI
errDestexhe, Alain; Hughes, Stuart W.; Rudolph, Michelle; Crunelli, Vincenzo
err分享
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Thalamic T-type Ca2+ channels and NREM sleep
errCELL CALCIUM
IF4
err2006-08-01
err127
errOAAI
errCrunelli, Vincenzo; Cope, David W.; Hughes, Stuart W.
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Thalamic mechanisms of EEG alpha rhythms and their pathological implications
errNEUROSCIENTIST
IF3.9
err2005-08-01
err450
PREAI
errHughes, SW; Crunelli, V
err分享
err收藏
Synchronized oscillations at α and θ frequencies in the lateral geniculate nucleus
errNEURON
IF15
err2004-04-01
err241
errOAAI
errHughes, SW; Lörincz, M; Cope, DW; Blethyn, KL; Kékesi, KA; Parri, HR; Juhász, G; Crunelli, V
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Novel neuronal and astrocytic mechanisms in thalamocortical loop dynamics丘脑皮质环动力学中新的神经元和星形细胞机制
errPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
IF4.7
err2002-12-29
err45
errOAAI
errCrunelli, V; Blethyn, KL; Cope, DW; Hughes, SW; Parri, HR; Turner, JP; Tòth, TI; Williams, SR
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Cellular mechanisms of the slow (<1 Hz) oscillation in thalamocortical neurons in vitro
errNEURON
IF15
err2002-03-01
err202
errOAAI
errHughes, SW; Cope, DW; Blethyn, KL; Crunelli, V
err分享
err收藏

研究方向

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合作学者
合作期刊
S
Steven R. Cummings
H 指数: 167 · 论文数: 944
T
T. G. McCarthy
H 指数: 141 · 论文数: 1.6K
A
Atul Malhotra
H 指数: 114 · 论文数: 1.1K
I
Ignacio Melero
H 指数: 108 · 论文数: 1.1K
T
Timothy A. Yap
H 指数: 77 · 论文数: 1.4K
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