未登录 Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes (vol 23, 50, 2024) Gamez, Monica; Elhegni, Hesham E.; Fawaz, Sarah; Ho, Kwan Ho; Campbell, Neill W.; Copland, David A.; Onions, Karen L.; Butler, Matthew J.; Wasson, Elizabeth J.; Crompton, Michael; Ramnath, Raina D.; Qiu, Yan; Yamaguchi, Yu; Arkill, Kenton P.; Bates, David O.; Turnbull, Jeremy E.; Zubkova, Olga V.; Welsh, Gavin I.; Atan, Denize; Satchell, Simon C.; Foster, Rebecca R. 分享 收藏
Heparanase inhibition as a systemic approach to protect the endothelial glycocalyx and prevent microvascular complications in diabetes Gamez, Monica; Elhegni, Hesham E.; Fawaz, Sarah; Ho, Kwan Ho; Campbell, Neill W.; Copland, David A.; Onions, Karen L.; Butler, Matthew J.; Wasson, Elizabeth J.; Crompton, Michael; Ramnath, Raina D.; Qiu, Yan; Yamaguchi, Yu; Arkill, Kenton P.; Bates, David O.; Turnbull, Jeremy E.; Zubkova, Olga V.; Welsh, Gavin I.; Atan, Denize; Satchell, Simon C.; Foster, Rebecca R. 分享 收藏
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Low sulfated heparan sulfate mimetic differentially affects repair in immune-mediated and toxin-induced experimental models of demyelination Lindsay, Susan L.; McCanney, George A.; Zhan, Jiangshan; Scheld, Miriam; Smith, Rebecca Sherrard; Goodyear, Carl S.; Yates, Edwin A.; Kipp, Markus; Turnbull, Jeremy E.; Barnett, Susan C. 分享 收藏
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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors Gray, Anna L.; Karlsson, Richard; Roberts, Abigail R. E.; Ridley, Amanda J. L.; Pun, Nabina; Khan, Bakhtbilland; Lawless, Craig; Luis, Rafael; Szpakowska, Martyna; Chevigne, Andy; Hughes, Catherine E.; Medina-Ruiz, Laura; Birchenough, Holly L.; Mulholland, Iashia Z.; Salanga, Catherina L.; Yates, Edwin A.; Turnbull, Jeremy E.; Handel, Tracy M.; Graham, Gerard J.; Jowitt, Thomas A.; Schiessl, Ingo; Richter, Ralf P.; Miller, Rebecca L.; Dyer, Douglas P. 分享 收藏
Evidence for multiple binding modes in the initial contact between SARS-CoV-2 spike S1 protein and cell surface glycans SARS-CoV-2刺突S1蛋白与细胞表面聚糖初始接触中存在多种结合模式的证据 Parafioriti, Michela; Ni, Minghong; Petitou, Maurice; Mycroft-West, Courtney J.; Rudd, Timothy R.; Gandhi, Neha S.; Ferro, Vito; Turnbull, Jeremy E.; Lima, Marcelo A.; Skidmore, Mark A.; Fernig, David G.; Yates, Edwin A.; Bisio, Antonella; Guerrini, Marco; Elli, Stefano 分享 收藏
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction Guimond, Scott E.; Mycroft-West, Courtney J.; Gandhi, Neha S.; Tree, Julia A.; Le, Thuy T.; Spalluto, C. Mirella; Humbert, Maria, V; Buttigieg, Karen R.; Coombes, Naomi; Elmore, Michael J.; Wand, Matthew; Nystrom, Kristina; Said, Joanna; Setoh, Yin Xiang; Amarilla, Alberto A.; Modhiran, Naphak; Sng, Julian D. J.; Chhabra, Mohit; Young, Paul R.; Rawle, Daniel J.; Lima, Marcelo A.; Yates, Edwin A.; Karlsson, Richard; Miller, Rebecca L.; Chen, Yen-Hsi; Bagdonaite, Ieva; Yang, Zhang; Stewart, James; Dung Nguyen; Laidlaw, Stephen; Hammond, Edward; Dredge, Keith; Wilkinson, Tom M. A.; Watterson, Daniel; Khromykh, Alexander A.; Suhrbier, Andreas; Carroll, Miles W.; Trybala, Edward; Bergstrom, Tomas; Ferro, Vito; Skidmore, Mark A.; Turnbull, Jeremy E. 分享 收藏
Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates 解剖3-o-硫酸化肝素和工程硫酸乙酰肝素的结构-功能 Karlsson, Richard; Chopra, Pradeep; Joshi, Apoorva; Yang, Zhang; Vakhrushev, Sergey Y.; Clausen, Thomas Mandel; Painter, Chelsea D.; Szekeres, Gergo P.; Chen, Yen-Hsi; Sandoval, Daniel R.; Hansen, Lars; Esko, Jeffrey D.; Pagel, Kevin; Dyer, Douglas P.; Turnbull, Jeremy E.; Clausen, Henrik; Boons, Geert-Jan; Miller, Rebecca L. 分享 收藏
Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin 肝素通过SARS-CoV-2抑制细胞侵袭: Spike S1受体结合域与肝素相互作用的结构依赖性 Mycroft-West, Courtney J.; Su, Dunhao; Pagani, Isabel; Rudd, Timothy R.; Elli, Stefano; Gandhi, Neha S.; Guimond, Scott E.; Miller, Gavin J.; Meneghetti, Maria C. Z.; Nader, Helena B.; Li, Yong; Nunes, Quentin M.; Procter, Patricia; Mancini, Nicasio; Clementi, Massimo; Bisio, Antonella; Forsyth, Nicholas R.; Ferro, Vito; Turnbull, Jeremy E.; Guerrini, Marco; Fernig, David G.; Vicenzi, Elisa; Yates, Edwin A.; Lima, Marcelo A.; Skidmore, Mark A. 分享 收藏
Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations 普通肝素在治疗相关浓度下抑制活野生型SARS-CoV-2细胞感染性 Tree, Julia A.; Turnbull, Jeremy E.; Buttigieg, Karen R.; Elmore, Michael J.; Coombes, Naomi; Hogwood, John; Mycroft-West, Courtney J.; Lima, Marcelo A.; Skidmore, Mark A.; Karlsson, Richard; Chen, Yen-Hsi; Yang, Zhang; Spalluto, Cosma Mirella; Staples, Karl J.; Yates, Edwin A.; Gray, Elaine; Singh, Dave; Wilkinson, Tom; Page, Clive P.; Carroll, Miles W. 分享 收藏
Cryogenic Infrared Spectroscopy Reveals Structural Modularity in the Vibrational Fingerprints of Heparan Sulfate Diastereomers Lettow, Maike; Grabarics, Marko; Greis, Kim; Mucha, Eike; Thomas, Daniel A.; Chopra, Pradeep; Boons, Geert-Jan; Karlsson, Richard; Turnbull, Jeremy E.; Meijer, Gerard; Miller, Rebecca L.; von Helden, Gert; Pagel, Kevin 分享 收藏
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Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides Miller, Rebecca L.; Guimond, Scott E.; Schworer, Ralf; Zubkova, Olga V.; Tyler, Peter C.; Xu, Yongmei; Liu, Jian; Chopra, Pradeep; Boons, Geert-Jan; Grabarics, Marko; Manz, Christian; Hofmann, Johanna; Karlsson, Niclas G.; Turnbull, Jeremy E.; Struwe, Weston B.; Pagel, Kevin 分享 收藏
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Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy Zubkova, Olga V.; Ahmed, Yassir A.; Guimond, Scott E.; Noble, Sophia-Louise; Miller, John Holmes; Smith, Raymond Alexander Alfred; Nurcombe, Victor; Tyler, Peter C.; Weissmann, Marina; Vlodavsky, Israel; Turnbull, Jeremy E. 分享 收藏
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