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The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system 苯丙胺的代谢和心血管效应部分由中枢黑皮素系统介导。 Simonds, Stephanie E.; Pryor, Jack T.; Lam, Brian Y. H.; Dowsett, Georgina K.; Mustafa, Tomris; Munder, Astrid; Elysee, Kayla; Balland, Eglantine; Cowley, Lachlan O.; Yeo, Giles S. H.; Lawrence, Andrew; Spanswick, David C.; Cowley, Michael A. 分享 收藏
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Dapagliflozin partially restores reproductive function in MC4R KO obese female mice Cui, Ling; Tan, Chunlu; Huang, Lili; Wang, Weihao; Huang, Zhengxiang; Geng, Fang; Wu, Mengjun; Chen, Xiaolin; Cowley, Michael; Roelfsema, Ferdinand; Chen, Chen 分享 收藏
The melanocortin pathway and energy homeostasis: From discovery to obesity therapy 黑皮质素途径和能量稳态: 从发现到肥胖治疗 Yeo, Giles S. H.; Chao, Daniela Herrera Moro; Siegert, Anna-Maria; Koerperich, Zoe M.; Ericson, Mark D.; Simonds, Stephanie E.; Larson, Courtney M.; Luquet, Serge; Clarke, Iain; Sharma, Shubh; Clement, Karine; Cowley, Michael A.; Haskell-Luevano, Carrie; Van der Ploeg, Lex; Adan, Roger A. H. 分享 收藏
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Dapagliflozin restores insulin and growth hormone secretion in obese mice Huang, Zhengxiang; Huang, Lili; Wang, Chengjian; Zhu, Shanli; Qi, Xinzhou; Chen, Yang; Zhang, Yanjun; Cowley, Michael A.; Veldhuis, Johannes D.; Chen, Chen 分享 收藏
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Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons Roberts, Brandon L.; Bennett, Baylin J.; Bennett, Camdin M.; Carroll, Julie M.; Dalboge, Louise S.; Hall, Colin; Hassouneh, Wafa; Heppner, Kristy M.; Kirigiti, Melissa A.; Lindsley, Sarah R.; Tennant, Katherine G.; True, Cadence A.; Whittle, Andrew; Wolf, Anitra C.; Roberts, Charles T., Jr.; Tang-Christensen, Mads; Sleeman, Mark W.; Cowley, Michael A.; Grove, Kevin L.; Kievit, Paul 分享 收藏
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Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1 (vol 67, pg 2456, 2018) Pfuhlmann, Katrin; Schriever, Sonja C.; Baumann, Peter; Kabra, Dhiraj G.; Harrison, Luke; Mazibuko-Mbeje, Sithandiwe E.; Contreras, Raian E.; Kyriakou, Eleni; Simonds, Stephanie E.; Tiganis, Tony; Cowley, Michael A.; Woods, Stephen C.; Jastroch, Martin; Clemmensen, Christoffer; De Angelis, Meri; Schramm, Karl-Werner; Sattler, Michael; Messias, Ana C.; Tschop, Matthias H.; Pfluger, Paul T. 分享 收藏
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Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus 雷公藤红素通过抑制下丘脑中的蛋白酪氨酸磷酸酶PTP1B和TCPTP促进饮食诱导的肥胖的体重减轻 Kyriakou, Eleni; Schmidt, Stefanie; Dodd, Garron T.; Pfuhlmann, Katrin; Simonds, Stephanie E.; Lenhart, Dominik; Geerlof, Arie; Schriever, Sonja C.; De Angelis, Meri; Schramm, Karl-Werner; Plettenburg, Oliver; Cowley, Michael A.; Tiganis, Tony; Tschoep, Matthias H.; Pfluger, Paul T.; Sattler, Michael; Messias, Ana C. 分享 收藏
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes (vol 9, 4304, 2018) Clemmensen, Christoffer; Jall, Sigrid; Kleinert, Maximilian; Quarta, Carmelo; Gruber, Tim; Reber, Josefine; Sachs, Stephan; Fischer, Katrin; Feuchtinger, Annette; Karlas, Angelos; Simonds, Stephanie E.; Grandl, Gerald; Loher, Daniela; Sanchez-Quant, Eva; Keipert, Susanne; Jastroch, Martin; Hofmann, Susanna M.; Nascimento, Emmani B. M.; Schrauwen, Patrick; Ntziachristos, Vasilis; Cowley, Michael A.; Finan, Brian; Mueller, Timo D.; Tschoep, Matthias H. 分享 收藏
Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes Clemmensen, Christoffer; Jail, Sigrid; Kleinert, Maximilian; Quarta, Carmelo; Gruber, Tim; Reber, Josefine; Sachs, Stephan; Fischer, Katrin; Feuchtinger, Annette; Karlas, Angelos; Simonds, Stephanie E.; Grandl, Gerald; Loher, Daniela; Sanchez-Quant, Eva; Keipert, Susanne; Jastroch, Martin; Hofmann, Susanna M.; Nascimento, Emmani B. M.; Schrauwen, Patrick; Ntziachristos, Vasilis; Cowley, Michael A.; Finan, Brian; Mueller, Timo D.; Tschoep, Matthias H. 分享 收藏
Insulin regulates POMC neuronal plasticity to control glucose metabolism Dodd, Garron T.; Michael, Natalie J.; Lee-Young, Robert S.; Mangiafico, Salvatore P.; Pryor, Jack T.; Munder, Astrid C.; Simonds, Stephanie E.; Bruening, Jens Claus; Zhang, Zhong-Yin; Cowley, Michael A.; Andrikopoulos, Sofianos; Horvath, Tamas L.; Spanswick, David; Tiganis, Tony 分享 收藏