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E

Eric M. Desjardins

mcmaster university
H指数:21
被引数:2,835

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Inhibiting peripheral serotonin activates liver AMPK and reduces monocyte-derived macrophages and fibrosis

抑制外周血清素激活肝脏AMPK并减少单核细胞来源的巨噬细胞和纤维化

Cell Reports
IF6.9
2025-11-260
OAAI
Battsetseg Batchuluun; Tinne Thoné; Andre Djalalvandi; Russta Fayyazi; Parneet Deo; Julian M. Yabut; Sara Maggiore; Bavo Vanneste; Jaya Gautam; Logan K. Townsend; Elham Ahmadi; Maria Joy Therese Jabile; Marisa Morrow; Eric M. Desjardins; Evangelia E. Tsakiridis; Sonia Rehal; Waliul I. Khan; Dongdong Wang; Charlotte L. Scott; Gregory R. Steinberg
ACLY inhibition promotes tumour immunity and suppresses liver cancer

ACLY抑制促进肿瘤免疫和抑制肝癌

Nature
IF48.5
2025-07-300
OA
Jaya Gautam; Jianhan Wu; James S. V. Lally; Jamie D. McNicol; Russta Fayyazi; Elham Ahmadi; Daniela Carmen Oniciu; Spencer Heaton; Roger S. Newton; Sonia Rehal; Dipankar Bhattacharya; Fiorella Di Pastena; Binh Nguyen; Celina M. Valvano; Logan K. Townsend; Suhrid Banskota; Battsetseg Batchuluun; Maria Joy Therese Jabile; Alice Payne; Junfeng Lu; Eric M. Desjardins; Naoto Kubota; Evangelia E. Tsakiridis; Bejal Mistry; Alex Aganostopoulos; Vanessa Houde; Ann Dansercoer; Koen H. G. Verschueren; Savvas N. Savvides; Joanne A. Hammill; Ksenia Bezverbnaya; Paola Muti; Theodoros Tsakiridis; Wenting Dai; Lei Jiang; Yujin Hoshida; Mark Larché; Jonathan L. Bramson; Scott L. Friedman; Kenneth Verstraete; Dongdong Wang; Gregory R. Steinberg
GDF15 links adipose tissue lipolysis with anxiety

GDF15将脂肪组织脂解与焦虑联系起来

NATURE METABOLISM
IF20.8
2025-04-151
OA
Townsend, Logan K.; Wang, Dongdong; Knuth, Carly M.; Fayyazi, Russta; Mohammad, Ahmad; Becker, Lea J.; Tsakiridis, Evangelia E.; Desjardins, Eric M.; Patel, Zeel; Valvano, Celina M.; Lu, Junfeng; Payne, Alice E.; Itua, Ofure; Medak, Kyle D.; Marko, Daniel M.; Schertzer, Jonathan D.; Wright, David C.; Beaudette, Shawn M.; Morrison, Katherine M.; Carpentier, Andre C.; Blondin, Denis P.; Macpherson, Rebecca E. K.; Mccall, Jordan G.; Jeschke, Marc G.; Steinberg, Gregory R.
Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice
CELL REPORTS MEDICINE
IF10.6
2023-09-018
OAAI
Desjardins, Eric M.; Wu, Jianhan; Lavoie, Declan C. T.; Ahmadi, Elham; Townsend, Logan K.; Morrow, Marisa R.; Wang, Dongdong; Tsakiridis, Evangelia E.; Batchuluun, Battsetseg; Fayyazi, Russta; Kwiecien, Jacek M.; Tsakiridis, Theodoros; Lally, James S. V.; Pare, Guillaume; Pinkosky, Stephen L.; Steinberg, Gregory R.
The phosphorylation of AMPKß1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids

Ampkß 1的磷酸化对于增加自噬和维持线粒体稳态以响应脂肪酸至关重要

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2022-11-2112
OAAI
Desjardins, Eric M.; Smith, Brennan K.; Day, Emily A.; Ducommun, Serge; Sanders, Matthew J.; Nederveen, Joshua P.; Ford, Rebecca J.; Pinkosky, Stephen L.; Townsend, Logan K.; Gutgesell, Robert M.; Lu, Rachel; Sakamoto, Kei; Steinberg, Gregory R.
Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia

抑制ATP柠檬酸裂解酶可改善NASH，肝纤维化和血脂异常

CELL METABOLISM
IF30.9
2022-06-0195
OAAI
Morrow, Marisa R.; Batchuluun, Battsetseg; Wu, Jianhan; Ahmadi, Elham; Leroux, Julie M.; Mohammadi-Shemirani, Pedrum; Desjardins, Eric M.; Wang, Zhichao; Tsakiridis, Evangelia E.; Lavoie, Declan C. T.; Reihani, Amir; Smith, Brennan K.; Kwiecien, Jacek M.; Lally, James S., V; Nero, Tracy L.; Parker, Michael W.; Ask, Kjetil; Scott, John W.; Jiang, Lei; Pare, Guillaume; Pinkosky, Stephen L.; Steinberg, Gregory R.
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy

线粒体定位的AMPK对局部能量有反应，并有助于运动和能量应激诱导的线粒体自噬

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2021-09-07110
OA
Drake, Joshua C.; Wilson, Rebecca J.; Laker, Rhianna C.; Guan, Yuntian; Spaulding, Hannah R.; Nichenko, Anna S.; Shen, Wenqing; Shang, Huayu; Dorn, Maya, V; Huang, Kian; Zhang, Mei; Bandara, Aloka B.; Brisendine, Matthew H.; Kashatus, Jennifer A.; Sharma, Poonam R.; Young, Alexander; Gautam, Jitendra; Cao, Ruofan; Wallrabe, Horst; Chang, Paul A.; Wong, Michael; Desjardins, Eric M.; Hawley, Simon A.; Christ, George J.; Kashatus, David F.; Miller, Clint L.; Wolf, Matthew J.; Periasamy, Ammasi; Steinberg, Gregory R.; Hardie, D. Grahame; Yan, Zhen
Compound- and fiber type-selective requirement of AMPKy3 for insulin-independent glucose uptake in skeletal muscle

AMPKy3对骨骼肌中胰岛素非依赖性葡萄糖摄取的化合物和纤维类型选择性要求

MOLECULAR METABOLISM
IF6.6
2021-09-0119
OAAI
Rhein, Philipp; Desjardins, Eric M.; Rong, Ping; Ahwazi, Danial; Bonhoure, Nicolas; Stolte, Jens; Santos, Matthieu D.; Ovens, Ashley J.; Ehrlich, Amy M.; Garcia, Jose L. Sanchez; Ouyang, Qian; Yabut, Julian M.; Membrez, Mathieu; Kjolby, Mads; Jessen, Niels; Oakhill, Jonathan S.; Treebak, Jonas T.; Maire, Pascal; Scott, John W.; Sanders, Matthew J.; Descombes, Patrick; Chen, Shuai; Steinberg, Gregory R.; Sakamoto, Kei
Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota
CELL REPORTS MEDICINE
IF10.6
2021-09-0129
OAAI
Ahmed, Basma A.; Ong, Frank J.; Barra, Nicole G.; Blondin, Denis P.; Gunn, Elizabeth; Oreskovich, Stephan M.; Szamosi, Jake C.; Syed, Saad A.; Hutchings, Emily K.; Konyer, Norman B.; Singh, Nina P.; Yabut, Julian M.; Desjardins, Eric M.; Anhe, Fernando F.; Foley, Kevin P.; Holloway, Alison C.; Noseworthy, Michael D.; Haman, Francois; Carpentier, Andre C.; Surette, Michael G.; Schertzer, Jonathan D.; Punthakee, Zubin; Steinberg, Gregory R.; Morrison, Katherine M.
The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue
NATURE COMMUNICATIONS
IF15.7
2021-08-2759
OAAI
Wang, Bo; Tsakiridis, Evangelia E.; Zhang, Shuman; Llanos, Andrea; Desjardins, Eric M.; Yabut, Julian M.; Green, Alexander E.; Day, Emily A.; Smith, Brennan K.; Lally, James S., V; Wu, Jianhan; Raphenya, Amogelang R.; Srinivasan, Krishna A.; McArthur, Andrew G.; Kajimura, Shingo; Patel, Jagdish Suresh; Wade, Michael G.; Morrison, Katherine M.; Holloway, Alison C.; Steinberg, Gregory R.
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms

长链脂肪酰辅酶a酯通过AMPK β1同工型的变构控制来调节代谢

NATURE METABOLISM
IF20.8
2020-07-2789
OAAI
Pinkosky, Stephen L.; Scott, John W.; Desjardins, Eric M.; Smith, Brennan K.; Day, Emily A.; Ford, Rebecca J.; Langendorf, Christopher G.; Ling, Naomi X. Y.; Nero, Tracy L.; Loh, Kim; Galic, Sandra; Hoque, Ashfaqul; Smiles, William J.; Ngoei, Kevin R. W.; Parker, Michael W.; Yan, Yan; Melcher, Karsten; Kemp, Bruce E.; Oakhill, Jonathan S.; Steinberg, Gregory R.

研究方向

暂未获取到该数据
G
Gregory R. Steinberg
H 指数:89论文数:356被引数:3.2万
B
Brennan K. Smith
H 指数:31论文数:49被引数:4,538
E
Emily A. Day
H 指数:23论文数:50被引数:3,794
J
Julian M. Yabut
H 指数:10论文数:23被引数:1,664
L
Logan K. Townsend
H 指数:27论文数:81被引数:2,542
J
James Lally
H 指数:26论文数:54被引数:4,174
R
Rebecca J. Ford
H 指数:32论文数:93被引数:6,592
J
Jonathan D. Schertzer
H 指数:58论文数:223被引数:1.4万
J
Jianhan Wu
H 指数:10论文数:22被引数:541
E
Evangelia E. Tsakiridis
H 指数:10论文数:25被引数:708