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T

Takahiro Seki

kumamoto university
H指数:33
被引数:3,242

个人简介

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荣誉奖项

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Aromatic-Turmerone Analogs Activate Chaperone-Mediated Autophagy and Ameliorate Dendritic Shrinkage in Purkinje Cell Models of Spinocerebellar Ataxia

芳香-姜黄烯类似物激活伴侣介导的自噬并改善脊髓小脑共济失调浦肯野细胞模型中的树突萎缩

BIOLOGICAL & PHARMACEUTICAL BULLETIN
IF1.7
2026-05-010
PRE
Motomura, Kensuke; Ueda-Ishizaka, Erika; Boateng, Alex; Sugiura, Masaharu; Konno, Ayumu; Yabuki, Yasushi; Hitora-Imamura, Natsuko; Kurauchi, Yuki; Shioda, Norifumi; Masuda, Satohiro; Hirai, Hirokazu; Katsuki, Hiroshi; Seki, Takahiro
Inability of α-cyclodextrins to accommodate cholesterol potentially underlies their lack of efficacy and ototoxicity in Niemann-Pick disease type C treatment

α-环糊精无法容纳胆固醇，这可能是其治疗尼曼-匹克C型病缺乏疗效和具有耳毒性的潜在原因。

Scientific Reports
IF3.9
2025-08-220
OAAI
Yusei Yamada; Mayuko Tanaka; Yusei Ikeda; Yuki Kondo; Toru Takeo; Naomi Nakagata; Toru Miwa; Hiroki Takeda; Yorihisa Orita; Keiichi Motoyama; Taishi Higashi; Hidetoshi Arima; Takahiro Seki; Yuki Kurauchi; Hiroshi Katsuki; Katsumi Higaki; Kotaro Matsusaka; Kentaro Minami; Naoki Yoshikawa; Ryuji Ikeda; Muneaki Matsuo; Tetsumi Irie; Yoichi Ishitsuka
Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann-Pick disease type C treatment
CLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
2023-08-246
OAAI
Yamada, Yusei; Fukaura-Nishizawa, Madoka; Nishiyama, Asami; Ishii, Akira; Kawata, Tatsuya; Shirakawa, Aina; Tanaka, Mayuko; Kondo, Yuki; Takeo, Toru; Nakagata, Naomi; Miwa, Toru; Takeda, Hiroki; Orita, Yorihisa; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Seki, Takahiro; Kurauchi, Yuki; Katsuki, Hiroshi; Higaki, Katsumi; Minami, Kentaro; Yoshikawa, Naoki; Ikeda, Ryuji; Matsuo, Muneaki; Irie, Tetsumi; Ishitsuka, Yoichi
Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss
BIOMEDICINE & PHARMACOTHERAPY
IF7.5
2022-11-015
OAAI
Yamada, Yusei; Miwa, Toru; Nakashima, Masaki; Shirakawa, Aina; Ishii, Akira; Namba, Nanami; Kondo, Yuki; Takeo, Toru; Nakagata, Naomi; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Kurauchi, Yuki; Seki, Takahiro; Katsuki, Hiroshi; Okada, Yasuyo; Ichikawa, Atsushi; Higaki, Katsumi; Hayashi, Ken; Minami, Kentaro; Yoshikawa, Naoki; Ikeda, Ryuji; Ishikawa, Yoshihide; Kajii, Tomohito; Tachii, Kyoko; Takeda, Hiroki; Orita, Yorihisa; Matsuo, Muneaki; Irie, Tetsumi; Ishitsuka, Yoichi
Differential mode of cholesterol inclusion with 2-hydroxypropyl-cyclodextrins increases safety margin in treatment of Niemann-Pick disease type C

胆固醇与2-羟丙基-环糊精的差异模式增加了C型niemann-pick疾病治疗的安全范围

BRITISH JOURNAL OF PHARMACOLOGY
IF7.7
2021-05-1212
OAAI
Yamada, Yusei; Ishitsuka, Yoichi; Kondo, Yuki; Nakahara, Shuichi; Nishiyama, Asami; Takeo, Toru; Nakagata, Naomi; Motoyama, Keiichi; Higashi, Taishi; Arima, Hidetoshi; Kamei, Shunsuke; Shuto, Tsuyoshi; Kai, Hirofumi; Hayashino, Yuji; Sugita, Masatake; Kikuchi, Takeshi; Hirata, Fumio; Miwa, Toru; Takeda, Hiroki; Orita, Yorihisa; Seki, Takahiro; Ohta, Tomoko; Kurauchi, Yuki; Katsuki, Hiroshi; Matsuo, Muneaki; Higaki, Katsumi; Ohno, Kousaku; Matsumoto, Shirou; Era, Takumi; Irie, Tetsumi

研究方向

暂未获取到该数据
H
Hiroshi Katsuki
H 指数:51论文数:363被引数:9,403
Y
Yuki Kurauchi
H 指数:24论文数:151被引数:1,630
N
Norio Sakai
H 指数:35论文数:207被引数:4,463
A
Akinori Hisatsune
H 指数:27论文数:144被引数:2,105
N
Naoaki Saito
H 指数:58论文数:365被引数:1.0万
N
Naoko Adachi
H 指数:17论文数:48被引数:930
S
Shigeru Tanaka
H 指数:26论文数:145被引数:2,575
I
Izumi Hide
H 指数:29论文数:118被引数:3,288
H
Hirokazu Hirai
H 指数:49论文数:347被引数:8,840
A
Ayumu Konno
H 指数:25论文数:126被引数:2,885