Data-Independent Acquisition-Parallel Reaction Monitoring Acquisition Reveals Age-Dependent Alterations of the Lysosomal Proteome in a Mouse Model of Metachromatic LeukodystrophyANALYTICAL CHEMISTRYIF6.72024-12-020PRE
Engineered arylsulfatase A with increased activity, stability and brain delivery for therapy of metachromatic leukodystrophyMOLECULAR THERAPYIF122023-10-010PRE
Neurodegenerative disease after hematopoietic stem cell transplantation in metachromatic leukodystrophyANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGYIF3.92023-05-228OA
Sulfatide accumulation begins as early as four months of age in ARSA knockout miceMOLECULAR GENETICS AND METABOLISMIF3.52022-02-010PRE
Deletion of fatty acid amide hydrolase reduces lyso-sulfatide levels but exacerbates metachromatic leukodystrophy in miceJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92021-09-012OAAI
Brain cell type-specific endocytosis of arylsulfatase A identifies limitations of enzyme-based therapies for metachromatic leukodystrophyHUMAN MOLECULAR GENETICSIF3.22020-12-2615PREAI
Metachromatic leukodystrophy and transplantation: remyelination, no cross-correctionANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGYIF3.92020-01-2244OAAI
Evolutionary redesign of the lysosomal enzyme arylsulfatase A increases efficacy of enzyme replacement therapy for metachromatic leukodystrophyHUMAN MOLECULAR GENETICSIF3.22019-01-1813PREAI
Potential of surfactant-coated nanoparticles to improve brain delivery of arylsulfatase AJOURNAL OF CONTROLLED RELEASEIF11.52017-05-0133PREAI
Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic LeukodystrophyMOLECULAR THERAPYIF122015-09-0144OAAI
Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic LeukodystrophyMOLECULAR THERAPYIF122015-07-0140OAAI
Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with ageHUMAN MOLECULAR GENETICSIF3.22012-03-0248OAAI
Transport of Arylsulfatase A across the Blood-Brain Barrier in VitroJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92011-05-0123OAAI
Intracerebroventricular enzyme infusion corrects central nervous system pathology and dysfunction in a mouse model of metachromatic leukodystrophyHUMAN MOLECULAR GENETICSIF3.22011-04-2276OAAI
Quantitative genotyping of single-nucleotide polymorphisms by allele-specific oligonucleotide hybridization on DNA microarraysBIOTECHNOLOGY AND APPLIED BIOCHEMISTRYIF2.72010-12-239OAAI
Site-specific analysis of N-linked oligosaccharides of recombinant lysosomal arylsulfatase A produced in different cell linesGLYCOBIOLOGYIF3.32009-10-2818OAAI
Enzyme Replacement Improves Ataxic Gait and Central Nervous System Histopathology in a Mouse Model of Metachromatic LeukodystrophyMOLECULAR THERAPYIF122009-04-0167OA
Saposin B-dependent Reconstitution of Arylsulfatase A Activity in Vitro and in Cell Culture Models of Metachromatic LeukodystrophyJOURNAL OF BIOLOGICAL CHEMISTRYIF3.92009-04-0122OAAI
Induction of tolerance to human arylsulfatase a in a mouse model of metachromatic leukodystrophyMOLECULAR MEDICINEIF6.42007-09-0125OAAI
Modest phenotypic improvements in ASA-deficient mice with only one UDP-galactose:ceramide-galactosyltransferase geneLIPIDS IN HEALTH AND DISEASEIF4.22006-01-012OAAI