Moritz M. Gaidt - Publications, H-index & Citations

Moritz M. Gaidt

Vienna Biocenter

21H指数

42论文数

4.3K被引数

收录论文 18

发表时间

Tonic and early interferons defend against respiratory viruses in primary human lung organoid-derived air-liquid interface cultures 基础和早期干扰素在原代人类肺类器官衍生的气-液界面培养物中抵抗呼吸道病毒

Journal of Virology

IF3.8

2026-05-01

PREAI

Sivarajan, Rinu; Kirchgatterer, Paul C.; Lawrenz, Jan; Tanner-Matiz, Eszter; Lindenmayer, Jessica; Renz, Verena; Joshi, Tapan; Oberwinkler, Heike; Walles, Thorsten; Fois, Giorgio; Kleger, Alexander; Frick, Manfred; Munch, Jan; Gaidt, Moritz M.; Steinke, Maria; Sparrer, Konstantin M. J.

Poxvirus attack of antiviral defense pathways unleashes an effector-triggered NF-κB response 痘病毒对抗病毒防御通路的攻击引发效应物触发的NF-κB反应

Science

IF45.8

2026-02-12

PREAI

Brenna C. Remick; Joshua Q. Mao; Andrew G. Manford; Ami D. Gutierrez-Jensen; Allon Wagner; Michael Rape; Grant McFadden; Masmudur M. Rahman; Moritz M. Gaidt; Russell E. Vance

Retinol Binding Protein 4 reactivates latent HIV-1 by triggering canonical NF-κB, JAK/STAT5 and JNK signalling 视黄醇结合蛋白4通过触发经典NF-κB、JAK/STAT5和JNK信号通路来重新激活潜伏的HIV-1。

Signal Transduction and Targeted Therapy

IF52.7

2025-10-03

OAAI

Chiara Pastorio; Khumoekae Richard; Shariq Usmani; Ann-Kathrin Kissmann; Grigory Bolotnikov; Guillermo Gosálbez; Manuel Hayn; Lennart Koepke; Alina Sauertnik; Andrea Preising; Nico Preising; Ludger Ständker; Matthew Fair; Jessicamarie Morris; Emmanouil Papasavvas; Qin Liu; Honghong Sun; Armando Rodríguez; Karam Mounzer; Sebastian Wiese; Pablo Tebas; Yangzhu Du; Gregory M. Laird; Markus Jaritz; Frank Rosenau; Moritz M. Gaidt; Konstantin M. J. Sparrer; Luis J. Montaner; Frank Kirchhoff

A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles 一种裂分位点E3连接酶机制使ZNFX1能够泛素化并聚集单链RNA，形成泛素包被的核蛋白颗粒。

Cell

IF42.5

2025-08-27

OAAI

Daniel B. Grabarczyk; Eric J. Aird; Vanessa Reznikow; Paul C. Kirchgatterer; Julian F. Ehrmann; Robert Kurzbauer; Lillie E. Bell; Max J. Kellner; Ritika Aggarwal; Alexander Schleiffer; Victoria Faas; Luiza Deszcz; Anton Meinhart; Gijs A. Versteeg; Josef M. Penninger; Lukas S. Stelzl; Moritz M. Gaidt; Ingrid Tessmer; Jacob E. Corn; Tim Clausen

Friendly fire: recognition of self by the innate immune system

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2024-10-01

OAAI

Hornung, Veit; Gaidt, Moritz M.

Effector-Triggered Immunity 效应物触发免疫

ANNUAL REVIEW OF IMMUNOLOGY

IF33.3

2023-04-26

OAAI

Remick, Brenna C.; Gaidt, Moritz M.; Vance, Russell E.

Tumor necrosis factor is a necroptosis-associated alarmin

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-12-12

OAAI

Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Nagl, Dennis; Kuut, Gunnar; Hornung, Veit

IKKO primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network

IMMUNITY

IF26.3

2022-12-01

OAAI

Schmacke, Niklas A.; O'Duill, Fionan; Gaidt, Moritz M.; Szymanska, Inga; Kamper, Julia M.; Schmid-Burgk, Jonathan L.; Maedler, Sophia C.; Mackens-Kiani, Timur; Kozaki, Tatsuya; Chauhan, Dhruv; Nagl, Dennis; Stafford, Che A.; Harz, Hartmann; Froehlich, Adrian L.; Pinci, Francesca; Ginhoux, Florent; Beckmann, Roland; Mann, Matthias; Leonhardt, Heinrich; Hornung, Veit

Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons

ELIFE

IF0

2021-06-21

OAAI

Ji, Daisy X.; Witt, Kristen C.; Kotov, Dmitri, I; Margolis, Shally R.; Louie, Alexander; Chevee, Victoria; Chen, Katherine J.; Gaidt, Moritz M.; Dhaliwal, Harmandeep S.; Lee, Angus Y.; Nishimura, Stephen L.; Zamboni, Dario S.; Kramnik, Igor; Portnoy, Daniel A.; Darwin, K. Heran; Vance, Russell E.

C-tag TNF: a reporter system to study TNF shedding C-tag TNF: 研究TNF脱落的报告系统

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-01

OAAI

Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Kuut, Gunnar; Jackson, Margaret A.; Bauernfried, Stefan; Hornung, Veit

Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency 遗传性Caspase-8缺乏症患者的肠道炎症和免疫失调

GASTROENTEROLOGY

IF25.1

2019-01-01

PREAI

Lehle, Anna S.; Farin, Henner F.; Marquardt, Benjamin; Michels, Birgitta E.; Magg, Thomas; Li, Yue; Liu, Yanshan; Ghalandary, Maryam; Lammens, Katja; Hollizeck, Sebastian; Rohlfs, Meino; Hauck, Fabian; Conca, Raffaele; Walz, Christoph; Weiss, Batia; Lev, Atar; Simon, Amos J.; Gross, Olaf; Gaidt, Moritz M.; Hornung, Veit; Clevers, Hans; Yazbeck, Nadine; Hanna-Wakim, Rima; Shouval, Dror S.; Warner, Neil; Somech, Raz; Muise, Aleixo M.; Snapper, Scott B.; Bufler, Philip; Koletzko, Sibylle; Klein, Christoph; Kotlarz, Daniel

Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases 人类RIPK1缺陷导致联合免疫缺陷和炎症性肠病

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-27

138

OAAI

Li, Yue; Fuehrer, Marita; Bahrami, Ehsan; Socha, Piotr; Klaudel-Dreszler, Maja; Bouzidi, Amira; Liu, Yanshan; Lehle, Anna S.; Magg, Thomas; Hollizeck, Sebastian; Rohlfs, Meino; Conca, Raffaele; Field, Michael; Warner, Neil; Mordechai, Slae; Shteyer, Eyal; Turner, Dan; Boukari, Rachida; Belbouab, Reda; Walz, Christoph; Gaidt, Moritz M.; Hornung, Veit; Baumann, Bernd; Pannicke, Ulrich; Al Idrissi, Eman; Alghamdi, Hamza Ali; Sepulveda, Fernando E.; Gil, Marine; Basile, Genevieve de Saint; Honig, Manfred; Koletzko, Sibylle; Muise, Aleixo M.; Snapper, Scott B.; Schwarz, Klaus; Klein, Christoph; Kotlarz, Daniel

BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages

CELL REPORTS

IF6.9

2018-11-01

OAAI

Chauhan, Dhruv; Bartok, Eva; Gaidt, Moritz M.; Bock, Florian J.; Herrmann, Jennifer; Seeger, Jens M.; Broz, Petr; Beckmann, Roland; Kashkar, Hamid; Tait, Stephen W. G.; Mueller, Rolf; Hornung, Veit

Alternative inflammasome activation enables IL-1β release from living cells

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2017-02-01

104

OAAI

Gaidt, Moritz M.; Hornung, Veit

Pore formation by GSDMD is the effector mechanism of pyroptosis

EMBO JOURNAL

IF8.3

2016-08-29

127

OAAI

Gaidt, Moritz M.; Hornung, Veit

Human Monocytes Engage an Alternative Inflammasome Pathway

IMMUNITY

IF26.3

2016-04-01

638

OAAI

Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Schmidt, Tobias; Schmid-Burgk, Jonathan L.; Rapino, Francesca; Robertson, Avril A. B.; Cooper, Matthew A.; Graf, Thomas; Hornung, Veit

Cytosolic RNA:DNA hybrids activate the cGAS-STING axis

EMBO JOURNAL

IF8.3

2014-11-25

273

OAAI

Mankan, Arun K.; Schmidt, Tobias; Chauhan, Dhruv; Goldeck, Marion; Hoening, Klara; Gaidt, Moritz; Kubarenko, Andrew V.; Andreeva, Liudmila; Hopfner, Karl-Peter; Hornung, Veit

Out Knocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines

GENOME RESEARCH

IF5.5

2014-09-03

110

OAAI

Schmid-Burgk, Jonathan L.; Schmidt, Tobias; Gaidt, Moritz M.; Pelka, Karin; Latz, Eicke; Ebert, Thomas S.; Hornung, Veit

研究方向