未登录AI-enhanced profiling of phage-display-identified anti-TIM3 and anti-TIGIT novel antibodies基于AI增强的、针对噬菌体展示法筛选出的抗TIM3和抗TIGIT新型抗体的分析
Musnier, Astrid; Corde, Yannick; Verdier, Adrien; Cortes, Melanie; Pallandre, Jean-Rene; Dumet, Christophe; Bouard, Adeline; Keskes, Abdelraouf; Omahdi, Zakaria; Puard, Vincent; Poupon, Anne; Bourquard, Thomas .png)
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收藏Bispecific antibodies tethering innate receptors induce human tolerant-dendritic cells and regulatory T cells束缚先天受体的双特异性抗体诱导人耐受树突状细胞和调节性T细胞Lamendour, Lucille; Gilotin, Maeelle; Nkor, Nora Deluce-Kakwata; Lakhrif, Zineb; Meley, Daniel; Poupon, Anne; Laboute, Thibaut; di Tommaso, Anne; Pin, Jean-Jacques; Mulleman, Denis; Le Meledo, Guillaume; Aubrey, Nicolas; Watier, Herve; Velge-Roussel, Florence 分享 收藏 Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warrantedAcar, Delphine Diana; Witkowski, Wojciech; Wejda, Magdalena; Wei, Ruifang; Desmet, Tim; Schepens, Bert; De Cae, Sieglinde; Sedeyn, Koen; Eeckhaut, Hannah; Fijalkowska, Daria; Roose, Kenny; Vanmarcke, Sandrine; Poupon, Anne; Jochmans, Dirk; Zhang, Xin; Abdelnabi, Rana; Foo, Caroline S.; Weynand, Birgit; Reiter, Dirk; Callewaert, Nico; Remaut, Han; Neyts, Johan; Saelens, Xavier; Gerlo, Sarah; Vandekerckhove, Linos 分享 收藏 TNB-738, a biparatopic antibody, boosts intracellular NAD plus by inhibiting CD38 ecto-enzyme activity双互补位抗体TNB-738通过抑制CD38胞外酶活性来增强细胞内NAD plusUgamraj, Harshad S.; Dang, Kevin; Ouisse, Laure-Helene; Buelow, Benjamin; Chini, Eduardo N.; Castello, Giulia; Allison, James; Clarke, Starlynn C.; Davison, Laura M.; Buelow, Roland; Deng, Rong; Iyer, Suhasini; Schellenberger, Ute; Manika, Sankar N.; Bijpuria, Shipra; Musnier, Astrid; Poupon, Anne; Cuturi, Maria Cristina; van Schooten, Wim; Dalvi, Pranjali 分享 收藏 Accurate determination of epitope for antibodies with unknown 3D structuresTahir, Shifa; Bourquard, Thomas; Musnier, Astrid; Jullian, Yann; Corde, Yannick; Omahdi, Zakaria; Mathias, Laetitia; Reiter, Eric; Crepieux, Pascale; Bruneau, Gilles; Poupon, Anne 分享 收藏 Agonist anti-ChemR23 mAb reduces tissue neutrophil accumulation and triggers chronic inflammation resolutionTrilleaud, C.; Gauttier, V; Biteau, K.; Girault, I; Belarif, L.; Mary, C.; Pengam, S.; Teppaz, G.; Thepenier, V; Danger, R.; Robert-Siegwald, G.; Neel, M.; Bruneau, S.; Glemain, A.; Neel, A.; Poupon, A.; Mosnier, J. F.; Chene, G.; Dubourdeau, M.; Blancho, G.; Vanhove, B.; Poirier, N. 分享 收藏 The RanBP2/RanGAP1-SUMO complex gates β-arrestin2 nuclear entry to regulate the Mdm2-p53 signaling axisBlondel-Tepaz, Elodie; Leverve, Marie; Sokrat, Badr; Paradis, Justine S.; Kosic, Milena; Saha, Kusumika; Auffray, Cedric; Lima-Fernandes, Evelyne; Zamborlini, Alessia; Poupon, Anne; Gaboury, Louis; Findlay, Jane; Baillie, George S.; Enslen, Herve; Bouvier, Michel; Angers, Stephane; Marullo, Stefano; Scott, Mark G. H. 分享 收藏 分享 收藏 4C3 Human Monoclonal Antibody: A Proof of Concept for Non-pathogenic Proteinase 3 Anti-neutrophil Cytoplasmic Antibodies in Granulomatosis With PolyangiitisGranel, Jerome; Lemoine, Roxane; Morello, Eric; Gallais, Yann; Mariot, Julie; Drapeau, Marion; Musnier, Astrid; Poupon, Anne; Pugniere, Martine; Seren, Seda; Nouar, Dalila; Gouilleux-Gruart, Valerie; Watier, Herve; Korkmaz, Brice; Hoarau, Cyrille 分享 收藏 The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRsLaboute, Thibaut; Gandia, Jorge; Pellissier, Lucie P.; Corde, Yannick; Rebeillard, Florian; Gallo, Maria; Gauthier, Christophe; Leaute, Audrey; Diaz, Jorge; Poupon, Anne; Kieffer, Brigitte L.; Le Merrer, Julie; Becker, Jerome A. J. 分享 收藏 Biased Signaling and Allosteric Modulation at the FSHRLandomiel, Flavie; De Pascali, Francesco; Raynaud, Pauline; Jean-Alphonse, Frederic; Yvinec, Romain; Pellissier, Lucie P.; Bozon, Veronique; Bruneau, Gilles; Crepieux, Pascale; Poupon, Anne; Reiter, Eric 分享 收藏 A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions回收抗转铁蛋白受体1单克隆抗体，通过靶标上调和抗体依赖性细胞毒性效应子功能有效治疗红白血病Neiveyans, Madeline; Melhem, Rana; Arnoult, Christophe; Bourquard, Thomas; Jarlier, Marta; Busson, Muriel; Laroche, Adrien; Cerutti, Martine; Pugniere, Martine; Ternant, David; Gaborit, Nadege; Chardes, Thierry; Poupon, Anne; Gouilleux-Gruart, Valerie; Pelegrin, Andre; Poul, Marie-Alix 分享 收藏 MAbTope: A Method for Improved Epitope MappingBourquard, Thomas; Musnier, Astrid; Puard, Vincent; Tahir, Shifa; Ayoub, Mohammed Akli; Jullian, Yann; Boulo, Thomas; Gallay, Nathalie; Watier, Herve; Bruneau, Gilles; Reiter, Eric; Crepieux, Pascale; Poupon, Anne 分享 收藏 分享 收藏 G protein-dependent signaling triggers a β-arrestin-scaffolded p70S6K/rpS6 module that controls 5′TOP mRNA translationTrefier, Aurelie; Musnier, Astrid; Landomiel, Flavie; Bourquard, Thomas; Boulo, Thomas; Ayoub, Mohammed Akli; Leon, Kelly; Bruneau, Gilles; Chevalier, Manon; Durand, Guillaume; Blache, Marie-Claire; Inoue, Asuka; Fontaine, Joel; Gauthier, Christophe; Tesseraud, Sophie; Reiter, Eric; Poupon, Anne; Crepieux, Pascale 分享 收藏 5B9, a monoclonal antiplatelet factor 4/heparin IgG with a human Fc fragment that mimics heparin-induced thrombocytopenia antibodiesKizlik-Masson, C.; Vayne, C.; McKenzi, S. E.; Poupon, A.; Zhou, Y.; Champier, G.; Pouplard, C.; Gruel, Y.; Rollin, J. 分享 收藏 β-arrestin signalling and bias in hormone-responsive GPCRsReiter, Eric; Ayoub, Mohammed Akli; Pellissier, Lucie P.; Landomiel, Flavie; Musnier, Astrid; Trefier, Aurelie; Gandia, Jorge; De Pascali, Francesco; Tahir, Shifa; Yvinec, Romain; Bruneau, Gilles; Poupon, Anne; Crepieux, Pascale 分享 收藏 Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challengesAyoub, Mohammed Akli; Crepieux, Pascale; Koglin, Markus; Parmentier, Marc; Pin, Jean-Philippe; Poupon, Anne; Reiter, Eric; Smit, Martine; Steyaert, Jan; Watier, Herve; Wilkinson, Trevor 分享 收藏 Postembryonic Fish Brain Proliferation Zones Exhibit Neuroepithelial-Type Gene Expression ProfileDambroise, Emilie; Simion, Matthieu; Bourquard, Thomas; Bouffard, Stephanie; Rizzi, Barbara; Jaszczyszyn, Yan; Bourge, Mickael; Affaticati, Pierre; Heuze, Aurelie; Jouralet, Julia; Edouard, Joanne; Brown, Spencer; Thermes, Claude; Poupon, Anne; Reiter, Eric; Sohm, Frederic; Bourrat, Franck; Joly, Jean-Stephane 分享 收藏 分享 收藏 
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