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M

Mariah J. Lelos

Cardiff University
H指数:14
被引数:1,103

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Cas9 nickase–mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington’s disease mouse model

Cas9 nuclease介导的CAG/CTG重复序列缩短与亨廷顿病小鼠模型表型改善相关

Science Translational Medicine
IF14.6
2026-10-210
PRE
Alvaro Murillo; Melanie Alpaugh; Ruban Rex Peter Durairaj; Emma L. Randall; Meghan Larin; Laura Heraty; Alys N. Aston; Alysha S. Taylor; Alex Mas Monteys; Nina Stöberl; Aeverie E. R. Heuchan; Pascale Aeschlimann; Kyle Fears; Christian Landles; Georgina F. Osborne; Antoine Mangin; Soumyasree Bhattacharyya; Emmanouil Metzakopian; Nicholas D. Allen; Jack Puymirat; Gillian P. Bates; Beverly L. Davidson; Francesca Cicchetti; Mariah J. Lelos; Vincent Dion
Imaging of human stem cell-derived dopamine grafts correlates with behavioural recovery and reveals microstructural brain changes

人类干细胞来源的多巴胺移植物成像与行为恢复相关，并揭示了微结构脑部变化

NEUROBIOLOGY OF DISEASE
IF5.6
2025-06-010
OAAI
Paisey, Stephen J.; Jones, Lucy R.; Harrison, David J.; Drummond, Nicola J.; Edwards, Olivia Z.; Canham, Maurice A.; Roberton, Victoria H.; Marshall, Christopher; Parker, Greg; Hills, Rachel; Rosser, Anne E.; Lane, Emma L.; Dunnett, Stephen B.; Kunath, Tilo; Assaf, Yaniv; Lelos, Mariah J.
The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease

TransEuro开放标签试验：人类胎儿腹侧中脑移植治疗中度帕金森病患者的临床研究

NATURE BIOTECHNOLOGY
IF41.7
2025-05-020
OA
Barker, Roger A.; Lao-Kaim, Nicholas P.; Guzman, Natalie Valle; Athauda, Dilan; Bjartmarz, Hjalmar; Bjoerklund, Anders; Church, Alistair; Cutting, Emma; Daft, Danielle; Dayal, Viswas; Dunnett, Stephen; Evans, Amy; Grealish, Shane; Hannaway, Naomi; He, Xiaoling; Hewitt, Sam; Kefalopoulou, Zinovia; Mahlknecht, Philipp; Martin-Bastida, Antonio; Farrell, Krista; Moore, Sarah; Bulstrode, Harry; Nakornchai, Tagore; Nelander-Wahlestedt, Jenny; Roupe, Linnea; Paul, Gesine; Peall, Kathryn; Rosser, Anne; Roca-Fernandez, Adriana; Rowlands, Sophie; Mcgorrian, Anne-Marie; Scherf, Caroline; Vinh, Ngoc Nga; Roberton, Victoria; Kelly, Claire; Lelos, Mariah; Torres, Eduardo; Shires, Kate; Hills, Rachel; Williams, Debbie; Roussakis, Andreas-Antonios; Sibley, Krista; Tyers, Pamela; Wijeyekoon, Ruwani; Williams-Gray, Caroline; Foltynie, Thomas; Piccini, Paola; Morris, Robert; Lazic, Stanley E.; Lindvall, Olle; Parmar, Malin; Widner, Hakan
Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2
EMBO MOLECULAR MEDICINE
IF8.3
2023-10-043
OAAI
Indrigo, Marzia; Morella, Ilaria; Orellana, Daniel; d'Isa, Raffaele; Papale, Alessandro; Parra, Riccardo; Gurgone, Antonia; Lecca, Daniela; Cavaccini, Anna; Tigaret, Cezar M.; Cagnotto, Alfredo; Jones, Kimberley; Brooks, Simon; Ratto, Gian Michele; Allen, Nicholas D.; Lelos, Mariah J.; Middei, Silvia; Giustetto, Maurizio; Carta, Anna R.; Tonini, Raffaella; Salmona, Mario; Hall, Jeremy; Thomas, Kerrie; Brambilla, Riccardo; Fasano, Stefania

研究方向

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S
Stephen B. Dunnett
H 指数:105论文数:1,496被引数:4.3万
A
Anne Rosser
H 指数:56论文数:435被引数:1.1万
S
Susanne Clinch
H 指数:9论文数:36被引数:195
M
Monica Busse
H 指数:37论文数:269被引数:4,941
E
Emma L. Lane
H 指数:21论文数:92被引数:1,718
S
Simon P. Brooks
H 指数:33论文数:128被引数:4,351
D
David J. Harrison
H 指数:21论文数:53被引数:1,766
V
Victoria H. Roberton
H 指数:10论文数:35被引数:501
R
Rachel Hills
H 指数:5论文数:15被引数:182
R
Roger A. Barker
H 指数:122论文数:966被引数:6.1万