Duncan E. Crombie

The University of Melbourne

H指数:21

被引数:1,227

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Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy

对散发型ALS患者来源的iPSC诱导运动神经元进行大规模药物筛选，识别出一种潜在的联合治疗方案

Nature Neuroscience

IF20

2025-11-240

OAAI

Christopher R. Bye; Elizabeth Qian; Katherine Lim; Maciej Daniszewski; Fleur C. Garton; Bảo C. Trần-Lê; Helena H. Liang; Tian Lin; John G. Lock; Duncan E. Crombie; Steven Morgan; Yi Hu; Samantha K. Barton; Lucy M. Palmer; Elvan Djouma; Saritha Kodikara; Kim-Anh Lê Cao; Thanuja Dharmadasa; Anjali K. Henders; Laura A. Ziser; Matthew C. Kiernan; Kevin Talbot; Merrilee Needham; Susan Fletcher; Paul Talman; Susan Mathers; Naomi R. Wray; Alex W. Hewitt; Alice Pebay; Bradley J. Turner

α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of amyotrophic lateral sclerosis

BRAIN COMMUNICATIONS

IF4.5

2022-03-311

OAAI

Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

GENOME BIOLOGY

IF9.4

2021-03-0552

OAAI

Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency

AGING-US