Michael A. Ihnat - Publications, H-index & Citations

Michael A. Ihnat

university of oklahoma system

37H指数

142论文数

5.4K被引数

收录论文 70

发表时间

Synthesis, molecular modeling, biological and pharmacokinetic evaluation of hydroxy pyrimidinones and pyrimidinediones as novel LDHA inhibitors 羟基嘧啶酮和嘧啶二酮的合成、分子建模、生物及药代动力学评价作为新型LDHA抑制剂

European Journal of Medicinal Chemistry

IF5.9

2025-09-14

PREAI

Horrick Sharma; Ty Elliott; Amery Good; Pragya Sharma; Somrita Mondal; Lerin Luckett Chastain; Michael A. Ihnat

Synthesis and biological characterization of an orally bioavailable lactate dehydrogenase-A inhibitor against pancreatic cancer 口服可生物利用的乳酸脱氢酶-胰腺癌抑制剂的合成和生物学特性

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-09-01

OAAI

Sharma, Horrick; Mondal, Somrita; Urquiza, Uzziah; Esparza, Colter; Bartlett, Seth; Santa -Pinter, Landon; Hill, Hanna; White, Madalyn; Sharma, Pragya; Luckett-Chastain, Lerin; Cooper, Anne; Rasel, Mohammad; Gao, Philip; Battaile, Kevin P.; Shukla, Surendra K.; Lovell, Scott; Ihnat, Michael A.

Precision nephrotoxicity testing using 3D in vitro models

CELL AND BIOSCIENCE

IF6.2

2023-12-21

OAAI

Yu, Pengfei; Zhu, Hainan; Bosholm, Carol Christine; Beiner, Daniella; Duan, Zhongping; Shetty, Avinash K.; Mou, Steve S.; Kramer, Philip Adam; Barroso, Luis F.; Liu, Hongbing; Cheng, Kun; Ihnat, Michael; Gorris, Matthew A.; Aloi, Joseph A.; Woldemichael, Jobira A.; Bleyer, Anthony; Zhang, Yuanyuan

Exploration of a Large Virtual Chemical Space: Identification of Potent Inhibitors of Lactate Dehydrogenase-A against Pancreatic Cancer

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2023-01-16

OAAI

Sharma, Horrick; Sharma, Pragya; Urquiza, Uzziah; Chastain, Lerin R.; Ihnat, Michael A.

Silk fibers assisted long-term 3D culture of human primary urinary stem cells via inhibition of senescence-associated genes: Potential use in the assessment of chronic mitochondrial toxicity

MATERIALS TODAY ADVANCES

IF8

2022-08-01

OAAI

Ding, Huifen; George, Sunil; Leng, Xiaoyan Iris; Ihnat, Michael; Ma, Jian-Xing; Jiang, Guochun; Margolis, David; Dumond, Julie; Zhang, Yuanyuan

3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity 人原代尿源性干细胞的3D球体评估药物诱导的线粒体毒性

PHARMACEUTICS

IF5.5

2022-05-11

OAAI

Ding, Huifen; Jambunathan, Kalyani; Jiang, Guochun; Margolis, David M.; Leng, Iris; Ihnat, Michael; Ma, Jian-Xing; Mirsalis, Jon; Zhang, Yuanyuan

TNF-Alpha as an Initiator of Allodynia and Anxiety-Like Behaviors in a Preclinical Model of PTSD and Comorbid Pain

FRONTIERS IN PSYCHIATRY

IF3.2

2021-08-25

OAAI

Dib, Patrick; Zhang, Yong; Ihnat, Michael A.; Gallucci, Randle M.; Standifer, Kelly M.

Innovative Approaches in the Battle Against Cancer Recurrence: Novel Strategies to Combat Dormant Disseminated Tumor Cells

FRONTIERS IN ONCOLOGY

IF3.3

2021-04-27

OAAI

Sauer, Scott; Reed, Damon R.; Ihnat, Michael; Hurst, Robert E.; Warshawsky, David; Barkan, Dalit

Potential of substituted quinazolines to interact with multiple targets in the treatment of cancer

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-04-01

OAAI

Choudhary, Shruti; Doshi, Arpit; Luckett-Chastain, Lerin; Ihnat, Michael; Hamel, Ernest; Mooberry, Susan L.; Gangjee, Aleem

The 3-D conformational shape of N-naphthyl-cyclopenta[d]pyrimidines affects their potency as microtubule targeting agents and their antitumor activity

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2021-01-01

OAAI

Xiang, Weiguo; Quadery, Tasdique M.; Hamel, Ernest; Luckett-Chastain, Lerin R.; Ihnat, Michael A.; Mooberry, Susan L.; Gangjee, Aleem

Geochemical characterization and renal cell toxicity of water-soluble extracts from US Gulf Coast lignite

ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

IF3.8

2018-10-01

PREAI

Ojeda, A. S.; Ford, S. D.; Gallucci, R. M.; Ihnat, M. A.; Philp, R. P.

FLLL32, a curcumin analog, ameliorates intestinal injury in necrotizing enterocolitis

inflammation research

IF4.1

2017-06-01

OAAI

Eckert, Jeffrey; Scott, Brian; Lawrence, Shelley M.; Ihnat, Michael; Chaaban, Hala

Interleukin (IL)-6 modulates transforming growth factor-β receptor I and II (TGF-βRI and II) function in epidermal keratinocytes

EXPERIMENTAL DERMATOLOGY

IF3.1

2017-03-08

OAAI

Luckett-Chastain, Lerin R.; Cottrell, Mackenzie L.; Kawar, Bethany M.; Ihnat, Michael A.; Gallucci, Randle M.

AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1 α stabilization

CANCER LETTERS

IF10.1

2017-03-01

OAAI

Bastian, Anja; Matsuzaki, Satoshi; Humphries, Kenneth M.; Pharaoh, Gavin A.; Doshi, Arpit; Zaware, Nilesh; Gangjee, Aleem; Ihnat, Michael A.

Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo [3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple -acting angiokinase inhibition as antitumor agents

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-01-01

OAAI

Pavana, Roheeth Kumar; Choudhary, Shruti; Bastian, Anja; Ihnat, Michael A.; Bai, Ruoli; Hamel, Ernest; Gangjee, Aleem

Design and biological evaluation of substituted pyrrolo[3,2-d]pyrimidines as dual acting RTK and microtubule targeting agents

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Gangjee, Aleem; Shah, Khushbu; Dybdal-Hargreaves, Nicholas; Mooberry, Susan; Bastian, Anja; Ihnat, Michael

Mechanistic evaluation of AG311-an OXPHOS inhibitor - as a potential treatment for breast cancer

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Bastian, Anja; Matsuzaki, Satoshi; Humphries, Kenneth M.; -Downs, Lora C. Bailey; Gangjee, Aleem; Ihnat, Michael A.

Design, synthesis, and biological evaluation of thieno[2,3-d] and thieno[3,2-d]pyrimidines as dual acting RTK inhibitors and microtubule targeting antitumor agents

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Gangjee, Aleem; Islam, Farhana; Quadery, Tasdique Mohammad; Mooberry, Susan L.; Bastian, Anja; Ihnat, Michael A.

Targeting dormant micrometastases: rationale, evidence to date and clinical implications 靶向休眠微转移: 原理，迄今为止的证据和临床意义

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY

IF4.2

2016-01-06

OAAI

Hurst, Robert E.; Bastian, Anja; Bailey-Downs, Lora; Ihnat, Michael A.

Novel small molecule AG311 induces tumor cell death through inhibition of mitochondrial electron transport

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Bastian, Anja; Bailey-Downs, Lora C.; Thorpe, Jessica E.; Devambatia, Ravi Kumar Vyas; Gangjee, Aleem; Humphries, Kenneth M.; Ihnat, Michael A.

研究方向