Derek S. Steele - Publications, H-index & Citations

Derek S. Steele

Faculty of Biological Sciences

27H指数

117论文数

2.4K被引数

收录论文 54

发表时间

Mechanisms of cardiomyocyte dysfunction induced by extracellular histones 细胞外组蛋白诱导的心肌细胞功能障碍机制

Cell Death Discovery

IF7

2026-07-27

OAAI

Moza M. Al-Owais; Zhaokang Yang; Derek S. Steele; Arun V. Holden

Super-Resolution Analysis of the Origins of the Elementary Events of ER Calcium Release in Dorsal Root Ganglion Neurons

CELLS

IF5.2

2023-12-23

OAAI

Hurley, Miriam E.; Shah, Shihab S.; Sheard, Thomas M. D.; Kirton, Hannah M.; Steele, Derek S.; Gamper, Nikita; Jayasinghe, Izzy

Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling

COMMUNICATIONS BIOLOGY

IF5.1

2023-06-19

OAAI

Al-Owais, Moza M.; Hettiarachchi, Nishani T.; Dallas, Mark L.; Scragg, Jason L.; Lippiat, Jonathan D.; Holden, Arun V.; Steele, Derek S.; Peers, Chris

A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types

METHODS

IF4.3

2021-09-01

OAAI

Hurley, Miriam E.; Sheard, Thomas M. D.; Norman, Ruth; Kirton, Hannah M.; Shah, Shihab S.; Pervolaraki, Eleftheria; Yang, Zhaokang; Gamper, Nikita; White, Ed; Steele, Derek; Jayasinghe, Izzy

Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1

SCIENTIFIC REPORTS

IF3.9

2021-04-14

OAAI

Dallas, Mark L.; Al-Owais, Moza M.; Hettiarachchi, Nishani T.; Vandiver, Matthew Scott; Jarosz-Griffiths, Heledd H.; Scragg, Jason L.; Boyle, John P.; Steele, Derek; Peers, Chris

Vascular Kv7 channels control intracellular Ca2+ dynamics in smooth muscle

CELL CALCIUM

IF4

2020-12-01

OAAI

Tsai, Yuan-Ming; Jones, Frederick; Mullen, Pierce; Porter, Karen E.; Steele, Derek; Peers, Chris; Gamper, Nikita

A Mechanism for Statin-Induced Susceptibility to Myopathy 他汀类药物诱发肌病易感性的机制

JACC-BASIC TO TRANSLATIONAL SCIENCE

IF7.2

2019-08-01

OAAI

Lotteau, Sabine; Ivarsson, Niklas; Yang, Zhaokang; Restagno, Damien; Colyer, John; Hopkins, Philip; Weightman, Andrew; Himori, Koichi; Yamada, Takashi; Bruton, Joseph; Steele, Derek; Westerblad, Hakan; Calaghan, Sarah

Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca2+ handling dysfunction in rats with pulmonary artery hypertension

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2018-07-01

OAAI

Fowler, Ewan D.; Drinkhill, Mark J.; Norman, Ruth; Pervolaraki, Eleftheria; Stones, Rachel; Steer, Emma; Benoist, David; Steele, Derek S.; Calaghan, Sarah C.; White, Ed

Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2018-02-05

OAAI

Venturi, Elisa; Lindsay, Chris; Lotteau, Sabine; Yang, Zhaokang; Steer, Emma; Witschas, Katja; Wilson, Abigail D.; Wickens, James R.; Russell, Angela J.; Steele, Derek; Calaghan, Sarah; Sitsapesan, Rebecca

The EPAC2 Inhibitor ESI-05 Prolongs the Action Potential and Increases Susceptibility to EAD Arrhythmias

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Kirton, Hannah M.; Al-Owais, Moza; Peers, Chris; Steele, Derek S.

Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5

CELL DEATH & DISEASE

IF9.6

2017-11-02

OAAI

Al-Owais, Moza M.; Hettiarachchi, Nishani T.; Boyle, John P.; Scragg, Jason L.; Elies, Jacobo; Dallas, Mark L.; Lippiat, Jon D.; Steele, Derek S.; Peers, Chris

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K+ channels in carbon monoxide-induced proarrhythmic early afterdepolarizations

FASEB JOURNAL

IF4.2

2017-07-25

OAAI

Al-Owais, Moza M.; Hettiarachchi, Nishani T.; Kirton, Hannah M.; Hardy, Matthew E.; Boyle, John P.; Scragg, Jason L.; Steele, Derek S.; Peers, Chris

Epac2-Rap1 Signaling Regulates Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2017-07-20

OAAI

Yang, Zhaokang; Kirton, Hannah M.; Al-Owais, Moza; Thireau, Jerome; Richard, Sylvain; Peers, Chris; Steele, Derek S.

Assessing the pathogenicity of RYR1 variants in malignant hyperthermia

BRITISH JOURNAL OF ANAESTHESIA

IF9.2

2017-04-01

OAAI

Merritt, A.; Booms, P.; Shaw, M-A.; Miller, D. M.; Daly, C.; Bilmen, J. G.; Stowell, K. M.; Allen, P. D.; Steele, D. S.; Hopkins, P. M.

Epac2-Rap1 Signaling Influences Reactive Oxygen Species Production and Susceptibility to Cardiac Arrhythmias

BIOPHYSICAL JOURNAL

IF3.1

2017-02-01

OAAI

Yang, Zhaokang; Kirton, Hannah M.; Al-Owais, Moza; Peers, Chris; Steele, Derek S.

Conditions that Promote Golgi Ca2+ Release Facilitate Trafficking of VEGFR-1 to the Surface Membrane in Rat Ventricular Myocytes

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Kirton, Hannah M.; Yang, Zhaokang; Steele, Derek S.

Simvastatin has Profound Effects on Sarcoplasmic Reticulum Ca2+ Leak in Skeletal but not Cardiac Muscle: A Mechanism for Myopathy

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Lotteau, Sabine; Yang, Zhaokang; Venturi, Elisa; Steer, Emma; Witschas, Katja; Sitsapesan, Rebecca; Steele, Derek; Calaghan, Sarah

Simvastatin Activates Single Skeletal RyR1 Channels but Exerts More Complex Regulation of the Cardiac Isoform, RyR2

BIOPHYSICAL JOURNAL

IF3.1

2016-02-01

OAAI

Venturi, Elisa; Witschas, Katja; Lotteau, Sabine J.; Steer, Emma; Steele, Derek S.; Calaghan, Sarah C.; Sitsapesan, Rebecca

The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway

SCIENCE SIGNALING

IF6.6

2015-10-13

OAAI

Yang, Zhaokang; Kirton, Hannah M.; MacDougall, David A.; Boyle, John P.; Deuchars, James; Frater, Brenda; Ponnambalam, Sreenivasan; Hardy, Matthew E.; White, Edward; Calaghan, Sarah C.; Peers, Chris; Steele, Derek S.

Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2015-09-01

OAAI

Fowler, Ewan D.; Benoist, David; Drinkhill, Mark J.; Stones, Rachel; Helmes, Michiel; Wust, Rob C. I.; Stienen, Ger J. M.; Steele, Derek S.; White, Ed

研究方向