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G

Gerwin Huls

University of Groningen
H指数:44
被引数:7,725

个人简介

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教育背景

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工作经历

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荣誉奖项

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Drivers of clinical resistance to venetoclax and hypomethylating agents in acute myeloid leukemia and strategies for improving efficacy

急性髓系白血病对维奈克拉和去甲基化药物的耐药机制及提高疗效的策略

HemaSphere
IF14.6
2026-01-110
OAAI
Ida Vänttinen; Joseph Saad; Tanja Ruokoranta; Sari Kytölä; Guangrong Qin; Bahar Tercan; Pia Ettala; Anu Partanen; Marja Pyörälä; Johanna Rimpiläinen; Timo Siitonen; Mikko Manninen; Peter J. M. Valk; Gerwin Huls; Vésteinn Thorsson; Caroline A. Heckman; Mika Kontro; Heikki Kuusanmäki
Decitabine conditioning improves NK cell maturation and limits CD8+ T cell terminal differentiation post-alloSCT in acute myeloid leukemia patients

地西他滨预处理可改善急性髓系白血病患者的alloSCT后NK细胞成熟并限制CD8+ T细胞终末分化。

Transplantation and Cellular Therapy
IF4.4
2025-11-290
OAAI
Jesper van Eck van der Sluijs; Diede van Ens; Ayla Grotens; Esther Fernández Merino; Nadia Dubois; Daan Heister; Theresia N. Scheele; Chrysanthi Kagiou; Nicolaas P.M. Schaap; Walter J.F.M. van der Velden; Suzanne van Dorp; Gerwin Huls; Joop H. Jansen; Jolanda Brummelman; Anniek B. van der Waart; Harry Dolstra; Willemijn Hobo
Metformin induces ferroptosis associated with lipidomic remodeling in AML

二甲双胍诱导与脂质组重塑相关的铁死亡在AML中

Blood Advances
IF7.1
2025-11-040
OAAI
Dominique Sternadt; Diego A. Pereira-Martins; Prodromos Chatzikyriakou; Luise Albuquerque-Simões; Ming Yang; Douglas R.A. Silveira; Albertus T.J. Wierenga; Isabel Weinhäuser; Shanna M. Hogeling; Lieve L. Oudejans; Pilar Casares Alaez; Jean-Emmanuel Sarry; Christian Frezza; Gerwin A. Huls; Lynn Quek; Jan Jacob Schuringa
Beneficial effect of PTCy and a short duration of immune suppression on relapse risk in acute myeloid leukemia patients with pretransplant MRD

PTCy和短期免疫抑制对移植前微小残留病（MRD）阳性的急性髓系白血病患者复发风险的有益影响

Bone Marrow Transplantation
IF5.2
2025-09-190
PRE
L. M. Morsink; K. Keijzer; C. L. E. Hazenberg; G. Choi; M. R. de Groot; E. Ammatuna; S. K. Klein; C. Woolthuis; A. Biswana; J. F. S. Meppelink; L. B. Bungener; K. Meijer; A. B. Mulder; G. Huls
A revised prognostic model for patients with acute myeloid leukemia and first relapse

针对急性髓系白血病首次复发的修订型预后模型

Blood Advances
IF7.1
2025-05-260
OA
Niek G. van der Maas; Dimitri Breems; Clara P. W. Klerk; Thomas Pabst; Patrycja Gradowska; Abin Thomas; Bart J. Biemond; Jurgen Kuball; Catharina H. M. J. Van Elssen; Otto Visser; Marie-Christiane Vekemans; Carlos Graux; Johan Maertens; Steven Knapper; Mike Dennis; Sylvie Freeman; Ian Thomas; H. Berna Beverloo; Gerwin Huls; Charles Craddock; Peter J. M. Valk; Paresh Vyas; Nigel Russell; Gert Ossenkoppele; Bob Löwenberg; Jan J. Cornelissen; Jurjen Versluis
The Oncogenic ΔNp73α Isoform Contributes to Aggressiveness in APL By Leading to ATRA Resistance through NANOG/BMP4 Axis Upregulation

癌基因ΔNp73α异构体通过上调NANOG/BMP4轴导致ATRA耐药性，从而促进APL的侵袭性。

BLOOD
IF23.1
2024-11-050
PRE
Rojas, Cesar Alexander Ortiz; Pereira-Martins, Diego A.; Thome, Carol; Ferreira, Germano; Bianco, Thiago Mantello; Weinhauser, Isabel; Silva, Cleide Lucia Araujo; Pontes, Lorena; Faca, Vitor; Ammatuna, Emanuele; Huls, Gerwin; Schuringa, Jan Jacob; Rego, Eduardo M.
The Oncogenic Function of the Intrinsically Disordered Transcriptional Regulator MN1 Depends on the Chaperone DNAJB6b

内源无序转录调控因子MN1的致癌功能依赖于分子伴侣DNAJB6b

BLOOD
IF23.1
2024-11-050
PRE
Pereira-Martins, Diego A.; van den Boom, Vincent; Weinhaeuser, Isabel; van der Meer, Nisha; Chatzikyriakou, Prodromos; van Dijk, Noortje; Zheng, Xuesen; Pinheiro, Lucio H.; Silveira, Douglas R. A.; Bianco, Thiago Mantello; Rojas, Cesar Alexander Ortiz; Rego, Eduardo M.; Rushworth, Stuart A.; Lucena-Araujo, Antonio R.; Quek, Lynn; Huls, Gerwin; Schuringa, Jan Jacob
Long-term survival can be achieved in a significant fraction of older patients with core-binding factor acute myeloid leukemia treated with intensive chemotherapy
HAEMATOLOGICA
IF7.9
2024-10-102
OAAI
Mosna, Federico; Borlenghi, Erika; Litzow, Mark; Byrd, John C.; Papayannidis, Cristina; Tecchio, Cristina; Ferrara, Felicetto; Marcucci, Guido; Cairoli, Roberto; Morgan, Elizabeth A.; Gurrieri, Carmela; Yeung, Cecilia C. S.; Deeg, H. Joachim; Capelli, Debora; Candoni, Anna; Gotlib, Jason R.; Lunghi, Monia; Pullarkat, Sheeja; Lanza, Francesco; Galimberti, Sara; Forghieri, Fabio; Venditti, Adriano; Festuccia, Moreno; Audisio, Ernesta; Marvalle, Denise; Rigolin, Gian Matteo; Roti, Giovanni; Dibona, Eros; Visani, Giuseppe; Albano, Francesco; Eisfeld, Ann-Kathrin; Valent, Peter; Huls, Gerwin; Borthakur, Gautam; Krampera, Mauro; Martinelli, Giovanni; Kroeger, Nicolaus; Sperotto, Alessandra; Gottardi, Michele
VISTA drives macrophages towards a pro-tumoral phenotype that promotes cancer cell phagocytosis yet down-regulates T cell responses

VISTA驱动巨噬细胞朝向促肿瘤表型，促进癌细胞吞噬作用，但下调T细胞反应

hematology oncology
IF13.5
2024-03-293
OAAI
Lin, Yusheng; Choukrani, Ghizlane; Dubbel, Lena; Rockstein, Lena; Freile, Jimena Alvarez; Qi, Yuzhu; Wiersma, Valerie; Zhang, Hao; Koch, Karl-Wilhelm; Ammatuna, Emanuele; Schuringa, Jan Jacob; van Meerten, Tom; Huls, Gerwin; Bremer, Edwin

研究方向

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J
Jan Jacob Schuringa
H 指数:48论文数:321被引数:6,889
J
Joop H. Jansen
H 指数:60论文数:365被引数:1.8万
I
Isabelle A. van Zeventer
H 指数:10论文数:28被引数:489
E
Emanuele Ammatuna
H 指数:30论文数:176被引数:3,714
B
Bert A. van der Reijden
H 指数:42论文数:193被引数:8,530
E
Edo Vellenga
H 指数:97论文数:846被引数:3.9万
D
Diego A. Pereira‐Martins
H 指数:16论文数:159被引数:867
A
Aniek O. de Graaf
H 指数:19论文数:74被引数:1,534
E
Eduardo Magalhães Rego
H 指数:44论文数:651被引数:8,331
A
Avinash G. Dinmohamed
H 指数:20论文数:136被引数:2,237