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收藏Virulence and genomic diversity among clinical isolates of ST1 (BI/NAP1/027) Clostridioides difficile艰难梭菌ST1 (BI/NAP1/027) 临床分离株的毒力和基因组多样性
Dong, Qiwen; Lin, Huaiying; Allen, Marie-Maude; Garneau, Julian R.; Sia, Jonathan K.; Smith, Rita C.; Haro, Fidel; McMillen, Tracy; Pope, Rosemary L.; Metcalfe, Carolyn; Burgo, Victoria; Woodson, Che; Dylla, Nicholas; Kohout, Claire; Sundararajan, Anitha; Snitkin, Evan S.; Young, Vincent B.; Fortier, Louis-Charles; Kamboj, Mini; Pamer, Eric G.
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收藏Clostridioides difficile S-Layer Protein A (SlpA) Serves as a General Phage Receptor
Royer, Alexia L. M.; Umansky, Andrew A.; Allen, Marie-Maude; Garneau, Julian R.; Ospina-Bedoya, Maicol; Kirk, Joseph A.; Govoni, Gregory; Fagan, Robert P.; Soutourina, Olga; Fortier, Louis-Charles
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收藏High-throughput identification of viral termini and packaging mechanisms in virome datasets using PhageTermVirome (vol 11, 18319, 2021)
Garneau, Julian R.; Legrand, Veronique; Marbouty, Martial; Press, Maximilian O.; Vik, Dean R.; Fortier, Louis-Charles; Sullivan, Matthew B.; Bikard, David; Monot, Marc
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收藏Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection
Smith-Peter, Erich; Seguin, David Lalonde; St-Pierre, Emilie; Sekulovic, Ognjen; Jeanneau, Simon; Tremblay-Tetreault, Cedrick; Lamontagne, Anne-Marie; Jacques, Pierre-Etienne; Lafontaine, Daniel A.; Fortier, Louis-Charles
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收藏In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials使用噬菌体递送的CRISPR-Cas3抗菌剂体内靶向艰难梭菌
Selle, Kurt; Fletcher, Joshua R.; Tuson, Hannah; Schmitt, Daniel S.; McMillan, Lana; Vridhambal, Gowrinarayani S.; Rivera, Alissa J.; Montgomery, Stephanie A.; Fortier, Louis-Charles; Barrangou, Rodolphe; Theriot, Casey M.; Ousterout, David G.
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收藏Multilocus Variable-Number Tandem-Repeat Analysis of Clostridioides difficile Clusters in Ribotype 027 Isolates and Lack of Association with Clinical Outcomes
Garneau, Julian R.; Abou Chakra, Claire Nour; Fortier, Louis-Charles; Labbe, Annie-Claude; Simor, Andrew E.; Gold, Wayne; Muller, Matthew; McGeer, Allison; Powis, Jeff; Katz, Kevin; Pepin, Jacques; Valiquette, Louis
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收藏Purine analogs targeting the guanine riboswitch as potential antibiotics against Clostridioides difficile
Yan, Lok-Hang; Le Roux, Antoine; Boyapelly, Kumaraswamy; Lamontagne, Anne-Marie; Archambault, Marie-Ann; Jean, Frederic Picard; Lalonde-Seguin, David; St-Pierre, Emilie; Najmanovich, Rafael J.; Fortier, Louis-Charles; Lafontaine, Daniel; Marsault, Eric
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