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Colorectal cancer-associated bacteria are broadly distributed in global microbiomes and drivers of precancerous change 结直肠癌相关细菌广泛分布于全球微生物组和癌前变化的驱动因素 Minot, Samuel S.; Li, Naisi; Srinivasan, Harini; Ayers, Jessica L.; Yu, Ming; Koester, Sean T.; Stangis, Mary M.; Dominitz, Jason A.; Halberg, Richard B.; Grady, William M.; Dey, Neelendu 分享 收藏
A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution Nardone, Stefano; De Luca, Roberto; Zito, Antonino; Klymko, Nataliya; Nicoloutsopoulos, Dimitris; Amsalem, Oren; Brannigan, Cory; Resch, Jon M.; Jacobs, Christopher L.; Pant, Deepti; Veregge, Molly; Srinivasan, Harini; Grippo, Ryan M.; Yang, Zongfang; Zeidel, Mark L.; Andermann, Mark L.; Harris, Kenneth D.; Tsai, Linus T.; Arrigoni, Elda; Verstegen, Anne M. J.; Saper, Clifford B.; Lowell, Bradford B. 分享 收藏
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A Point Mutation at C151 of Keap1 of Mice Abrogates NRF2 Signaling, Cytoprotection in Vitro, and Hepatoprotection in Vivo by Bardoxolone Methyl (CDDO-Me)S 小鼠Keap1 C151的点突变可消除NRF2信号传导，体外细胞保护作用以及Bardoxolone甲基 (CDDO-Me) 的体内肝脏保护作用 Gatbonton-Schwager, Tonibelle; Yagishita, Yoko; Joshi, Tanvi; Wakabayashi, Nobunao; Srinivasan, Harini; Suzuki, Takafumi; Yamamoto, Masayuki; Kensler, Thomas W. 分享 收藏
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis Sargsyan, Ashot; Doridot, Ludivine; Hannou, Sarah A.; Tong, Wenxin; Srinivasan, Harini; Ivison, Rachael; Monn, Ruby; Kou, Henry H.; Haldeman, Jonathan M.; Arlotto, Michelle; White, Phillip J.; Grimsrud, Paul A.; Astapova, Inna; Tsai, Linus T.; Herman, Mark A. 分享 收藏
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Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer Joanito, Ignasius; Wirapati, Pratyaksha; Zhao, Nancy; Nawaz, Zahid; Yeo, Grace; Lee, Fiona; Eng, Christine L. P.; Macalinao, Dominique Camat; Kahraman, Merve; Srinivasan, Harini; Lakshmanan, Vairavan; Verbandt, Sara; Tsantoulis, Petros; Gunn, Nicole; Venkatesh, Prasanna Nori; Poh, Zhong Wee; Nahar, Rahul; Oh, Hsueh Ling Janice; Loo, Jia Min; Chia, Shumei; Cheow, Lih Feng; Cheruba, Elsie; Wong, Michael Thomas; Kua, Lindsay; Chua, Clarinda; Nguyen, Andy; Golovan, Justin; Gan, Anna; Lim, Wan-Jun; Guo, Yu Amanda; Yap, Choon Kong; Tay, Brenda; Hong, Yourae; Chong, Dawn Qingqing; Chok, Aik-Yong; Park, Woong-Yang; Han, Shuting; Chang, Mei Huan; Seow-En, Isaac; Fu, Cherylin; Mathew, Ronnie; Toh, Ee-Lin; Hong, Lewis Z.; Skanderup, Anders Jacobsen; DasGupta, Ramanuj; Ong, Chin-Ann Johnny; Lim, Kiat Hon; Tan, Emile K. W.; Koo, Si-Lin; Leow, Wei Qiang; Tejpar, Sabine; Prabhakar, Shyam; Tan, Iain Beehuat 分享 收藏
Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b Patel, Suraj J.; Liu, Nan; Piaker, Sam; Gulko, Anton; Andrade, Maynara L.; Heyward, Frankie D.; Sermersheim, Tyler; Edinger, Nufar; Srinivasan, Harini; Emont, Margo P.; Westcott, Gregory P.; Luther, Jay; Chung, Raymond T.; Yan, Shuai; Kumari, Manju; Thomas, Reeby; Deleye, Yann; Tchernof, Andre; White, Phillip J.; Baselli, Guido A.; Meroni, Marica; De Jesus, Dario F.; Ahmad, Rasheed; Kulkarni, Rohit N.; Valenti, Luca; Tsai, Linus; Rosen, Evan D. 分享 收藏
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HGFAC Is a ChREBP-Regulated Hepatokine That Enhances Glucose and Lipid Homeostasis Sargsyan, Ashot; Doridot, Ludivine; Hannou, Sarah A.; Tong, Wenxin; Srinivasan, Harini; Ivison, Rachael; Monn, Ruby; Kou, Henry H.; Haldeman, Jonathan; Astapova, Inna; Tsai, Linus T.; Herman, Mark A. 分享 收藏
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A human expression system based on HEK293 for the stable production of recombinant erythropoietin Chin, Christine Lin; Goh, Justin Bryan; Srinivasan, Harini; Liu, Kaiwen Ivy; Gowher, Ali; Shanmugam, Raghuvaran; Lim, Hsueh Lee; Choo, Matthew; Tang, Wen Qin; Tan, Andy Hee-Meng; Terry Nguyen-Khuong; Tan, Meng How; Ng, Say Kong 分享 收藏
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates Shanmugam, Raghuvaran; Zhang, Fan; Srinivasan, Harini; Richard, John Lalith Charles; Liu, Kaiwen, I; Zhang, Xiujun; Woo, Cheok Wei A.; Chua, Zi Hao M.; Buschdorf, Jan Paul; Meaney, Michael J.; Tan, Meng How 分享 收藏
Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells Wang, Yuanming; Liu, Kaiwen Ivy; Sutrisnoh, Norfala-Aliah Binte; Srinivasan, Harini; Zhang, Junyi; Li, Jia; Zhang, Fan; Lalith, Charles Richard John; Xing, Heyun; Shanmugam, Raghuvaran; Foo, Jia Nee; Yeo, Hwee Ting; Ooi, Kean Hean; Bleckwehl, Tore; Par, Yi Yun Rachel; Lee, Shi Mun; Ismail, Nur Nadiah Binte; Sanwari, Nur Aidah Binti; Lee, Si Ting Vanessa; Lew, Jan; Tan, Meng How 分享 收藏
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Targeted lipidomics: Discovery of new fatty acyl amides Tan, Bo; Bradshaw, Heather B.; Rimmerman, Neta; Srinivasan, Harini; Yu, Y. William; Krey, Jocelyn F.; Monn, M. Francesca; Chen, Jay Shih-Chieh; hu, Sherry S-Jung Hu; Pickens, Sarah R.; Walker, J. Michael 分享 收藏
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