未登录 Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2 Lenart, Klara; Cerveira, Rodrigo Arcoverde; Hellgren, Fredrika; Ols, Sebastian; Sheward, Daniel J.; Kim, Changil; Cagigi, Alberto; Gagne, Matthew; Davis, Brandon; Germosen, Daritza; Roy, Vicky; Alter, Galit; Letscher, Helene; Van Wassenhove, Jerome; Gros, Wesley; Gallouet, Anne-Sophie; Le Grand, Roger; Kleanthous, Harry; Guebre-Xabier, Mimi; Murrell, Ben; Patel, Nita; Glenn, Gregory; Smith, Gale; Lore, Karin 分享 收藏
Enhancing Immunogenicity of a Thermostable, Efficacious SARS-CoV-2 Vaccine Formulation through Oligomerization and Adjuvant Choice Khan, Mohammad Suhail; Jakob, Virginie; Singh, Randhir; Rajmani, Raju S.; Kumar, Sahil; Lemoine, Celine; Kleanthous, Harry; Ringe, Rajesh P.; Dubois, Patrice M.; Varadarajan, Raghavan 分享 收藏
Effects of aluminum-salt, CpG and emulsion adjuvants on the stability and immunogenicity of a virus-like particle displaying the SARS-CoV-2 receptor-binding domain (RBD) Kumru, Ozan S.; Bajoria, Sakshi; Kaur, Kawaljit; Hickey, John M.; Van Slyke, Greta; Doering, Jennifer; Berman, Katherine; Richardson, Charles; Lien, Hans; Kleanthous, Harry; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants Mittal, Nidhi; Kumar, Sahil; Rajmani, Raju S.; Singh, Randhir; Lemoine, Celine; Jakob, Virginie; Sowrabha, B. J.; Jagannath, Nayana; Bhat, Madhuraj; Chakraborty, Debajyoti; Pandey, Suman; Jory, Aurelie; Soundarya, S. A. Suba; Kleanthous, Harry; Dubois, Patrice; Ringe, Rajesh P.; Varadarajan, Raghavan 分享 收藏
Antibody-mediated NK cell activation as a correlate of immunity against influenza infection Boudreau, Carolyn M.; Burke, John S.; Yousif, Ashraf S.; Sangesland, Maya; Jastrzebski, Sandra; Verschoor, Chris; Kuchel, George; Lingwood, Daniel; Kleanthous, Harry; De Bruijn, Iris; Landolfi, Victoria; Sridhar, Saranya; Alter, Galit 分享 收藏
Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018™ Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 RBD Antigen Bajoria, Sakshi; Kumru, Ozan S.; Doering, Jennifer; Berman, Katherine; Van Slyke, Greta; Prigodich, Anneka; Rodriguez-Aponte, Sergio A.; Kleanthous, Harry; Love, J. Christopher; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine 用AS03佐剂新型冠状病毒肺炎疫苗预防接种猕猴产生的针对sarbecovirus的广泛中和抗体 Feng, Yupeng; Yuan, Meng; Powers, John M.; Hu, Mengyun; Munt, Jennifer E.; Arunachalam, Prabhu S.; Leist, Sarah R.; Bellusci, Lorenza; Kim, JungHyun; Sprouse, Kaitlin R.; Adams, Lily E.; Sundaramurthy, Sumana; Zhu, Xueyong; Shirreff, Lisa M.; Mallory, Michael L.; Scobey, Trevor D.; Moreno, Alberto; O'Hagan, Derek T.; Kleanthous, Harry; Villinger, Francois J.; Veesler, David; King, Neil P.; Suthar, Mehul S.; Khurana, Surender; Baric, Ralph S.; Wilson, Ian A.; Pulendran, Bali 分享 收藏
Pre-existing Fc profiles shape the evolution of neutralizing antibody breadth following influenza vaccination Boudreau, Carolyn M.; Burke IV, John S.; Roederer, Alexander L.; Gorman, Matthew J.; Mundle, Sophia; Lingwood, Daniel; Delagrave, Simon; Sridhar, Saranya; Ross, Ted M.; Kleanthous, Harry; Alter, Galit 分享 收藏
Immunogenicity and protective efficacy of GBP510/AS03 vaccine against SARS-CoV-2 delta challenge in rhesus macaques GBP510/AS03疫苗对恒河猴SARS-CoV-2三角洲的免疫原性和保护作用 Jacob-Dolan, Catherine; Yu, Jingyou; McMahan, Katherine; Giffin, Victoria; Chandrashekar, Abishek; Martinot, Amanda J. J.; Anioke, Tochi; Powers, Olivia C. C.; Hall, Kevin; Hope, David; Miller, Jessica; Hachmann, Nichole P. P.; Chung, Benjamin; Gardner, Sarah; Sellers, Daniel; Barrett, Julia; Lewis, Mark G. G.; Andersen, Hanne; Kleanthous, Harry; Seo, Ki-Woen; Lee, Su Jeen; Park, Yong Wook; Kim, Hun; Barouch, Dan H. H. 分享 收藏
Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes Fan, Chengcheng; Cohen, Alexander A.; Park, Miso; Hung, Alfur Fu-Hsin; Keeffe, Jennifer R.; Gnanapragasam, Priyanthi N. P.; Lee, Yu E.; Gao, Han; Kakutani, Leesa M.; Wu, Ziyan; Kleanthous, Harry; Malecek, Kathryn E.; Williams, John C.; Bjorkman, Pamela J. 分享 收藏
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine 佐剂亚单位疫苗可诱导对SARS-CoV-2 Omicron变体的持久保护 Arunachalam, Prabhu S.; Feng, Yupeng; Ashraf, Usama; Hu, Mengyun; Walls, Alexandra C.; Edara, Venkata Viswanadh; Zarnitsyna, Veronika, I; Aye, Pyone Pyone; Golden, Nadia; Miranda, Marcos C.; Green, Kristyn W. M.; Threeton, Breanna M.; Maness, Nicholas J.; Beddingfield, Brandon J.; Bohm, Rudolf P.; Scheuermann, Sarah E.; Goff, Kelly; Dufour, Jason; Russell-Lodrigue, Kasi; Kepl, Elizabeth; Fiala, Brooke; Wrenn, Samuel; Ravichandran, Rashmi; Ellis, Daniel; Carter, Lauren; Rogers, Kenneth; Shirreff, Lisa M.; Ferrell, Douglas E.; Adhikary, Nihar R. Deb; Fontenot, Jane; Hammond, Holly L.; Frieman, Matthew; Grifoni, Alba; Sette, Alessandro; O'Hagan, Derek T.; Van der Most, Robbert; Rappuoli, Rino; Villinger, Francois; Kleanthous, Harry; Rappaport, Jay; Suthar, Mehul S.; Veesler, David; Wang, Taia T.; King, Neil P.; Pulendran, Bali 分享 收藏
Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants Bajoria, Sakshi; Kaur, Kawaljit; Kumru, Ozan S.; Van Slyke, Greta; Doering, Jennifer; Novak, Hayley; Rodriguez Aponte, Sergio A.; Dalvie, Neil C.; Naranjo, Christopher A.; Johnston, Ryan S.; Silverman, Judith Maxwell; Kleanthous, Harry; Love, J. Christopher; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. 分享 收藏
Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice 用临床相关佐剂辅助a亚单位SARS-CoV-2疫苗在小鼠中诱导持久保护 Grigoryan, Lilit; Lee, Audrey; Walls, Alexandra C.; Lai, Lilin; Franco, Benjamin; Arunachalam, Prabhu S.; Feng, Yupeng; Luo, Wei; Vanderheiden, Abigail; Floyd, Katharine; Wrenn, Samuel; Pettie, Deleah; Miranda, Marcos C.; Kepl, Elizabeth; Ravichandran, Rashmi; Sydeman, Claire; Brunette, Natalie; Murphy, Michael; Fiala, Brooke; Carter, Lauren; Coffman, Robert L.; Novack, David; Kleanthous, Harry; O'Hagan, Derek T.; van der Most, Robbert; McLellan, Jason S.; Suthar, Mehul; Veesler, David; King, Neil P.; Pulendran, Bali 分享 收藏
SARS-CoV-2 receptor binding domain displayed on HBsAg virus-like particles elicits protective immunity in macaques HBsAg病毒样颗粒上显示的SARS-CoV-2受体结合域在猕猴中引起保护性免疫 Dalvie, Neil C.; Tostanoski, Lisa H.; Rodriguez-Aponte, Sergio A.; Kaur, Kawaljit; Bajoria, Sakshi; Kumru, Ozan S.; Martinot, Amanda J.; Chandrashekar, Abishek; McMahan, Katherine; Mercado, Noe B.; Yu, Jingyou; Chang, Aiquan; Giffin, Victoria M.; Nampanya, Felix; Patel, Shivani; Bowman, Lesley; Naranjo, Christopher A.; Yun, Dongsoo; Flinchbaugh, Zach; Pessaint, Laurent; Brown, Renita; Velasco, Jason; Teow, Elyse; Cook, Anthony; Andersen, Hanne; Lewis, Mark G.; Camp, Danielle L.; Silverman, Judith Maxwell; Nagar, Gaurav S.; Rao, Harish D.; Lothe, Rakesh R.; Chandrasekharan, Rahul; Rajurkar, Meghraj P.; Shaligram, Umesh S.; Kleanthous, Harry; Joshi, Sangeeta B.; Volkin, David B.; Biswas, Sumi; Love, J. Christopher; Barouch, Dan H. 分享 收藏
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Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice Dalvie, Neil C.; Rodriguez-Aponte, Sergio A.; Hartwell, Brittany L.; Tostanoski, Lisa H.; Biedermann, Andrew M.; Crowell, Laura E.; Kaur, Kawaljit; Kumru, Ozan S.; Carter, Lauren; Yu, Jingyou; Chang, Aiquan; McMahan, Katherine; Courant, Thomas; Lebas, Celia; Lemnios, Ashley A.; Rodrigues, Kristen A.; Silva, Murillo; Johnston, Ryan S.; Naranjo, Christopher A.; Tracey, Mary Kate; Brady, Joseph R.; Whittaker, Charles A.; Yun, Dongsoo; Brunette, Natalie; Wang, Jing Yang; Walkey, Carl; Fiala, Brooke; Kar, Swagata; Porto, Maciel; Lok, Megan; Andersen, Hanne; Lewis, Mark G.; Love, Kerry R.; Camp, Danielle L.; Silverman, Judith Maxwell; Kleanthous, Harry; Joshi, Sangeeta B.; Volkin, David B.; Dubois, Patrice M.; Collin, Nicolas; King, Neil P.; Barouch, Dan H.; Irvine, Darrell J.; Love, J. Christopher 分享 收藏
Influenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans Jung, Jiwon; Mundle, Sophia T.; Ustyugova, Irina, V; Horton, Andrew P.; Boutz, Daniel R.; Pougatcheva, Svetlana; Prabakaran, Ponraj; McDaniel, Jonathan R.; King, Gregory R.; Park, Daechan; Person, Maria D.; Ye, Congxi; Tan, Bing; Tanno, Yuri; Kim, Jin Eyun; Curtis, Nicholas C.; DiNapoli, Joshua; Delagrave, Simon; Ross, Ted M.; Ippolito, Gregory C.; Kleanthous, Harry; Lee, Jiwon; Georgiou, George 分享 收藏
Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting Serological Breadth Qiu, Yu; Stegalkina, Svetlana; Zhang, Jianxin; Boudanova, Ekaterina; Park, Anna; Zhou, Yanfeng; Prabakaran, Ponraj; Pougatcheva, Svetlana; Ustyugova, Irina, V; Vogel, Thorsten U.; Mundle, Sophia T.; Oomen, Ray; Delagrave, Simon; Ross, Ted M.; Kleanthous, Harry; Qiu, Huawei 分享 收藏
Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector Giel-Moloney, M.; Esteban, M.; Oakes, B. H.; Vaine, M.; Asbach, B.; Wagner, R.; Mize, G. J.; Spies, A. G.; McElrath, J.; Perreau, M.; Roger, T.; Ives, A.; Calandra, T.; Weiss, D.; Perdiguero, B.; Kibler, K. V.; Jacobs, B.; Ding, S.; Tomaras, G. D.; Montefiori, D. C.; Ferrari, G.; Yates, N. L.; Roederer, M.; Kao, S. F.; Foulds, K. E.; Mayer, B. T.; Bennett, C.; Gottardo, R.; Parrington, M.; Tartaglia, J.; Phogat, S.; Pantaleo, G.; Kleanthous, H.; Pugachev, K. V. 分享 收藏
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