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陈

陈建欢 (Jian-Huan Chen)

Jiangnan University

H指数:26

被引数:1,617

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Paraspeckles translate microbial insult-induced inflammation into neurovascular remodeling by enhancing CYR61-FGF2 signaling via RBM14 sequestration

着丝粒小体通过增强CYR61-FGF2信号通路（经由RBM14隔离）将微生物刺激诱导的炎症转化为神经血管重塑

IF5.1

2026-09-240

PRE

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

基因校正增强帕金森病非人灵长类模型中的多巴胺能细胞疗法

Advanced Science

IF14.1

2026-07-060

OAAI

Association between ocular surface microbiota species and type 2 diabetes mellitus with or without retinopathy and related clinical parameters

结膜囊微生物菌群种类与有无视网膜病变的2型糖尿病及相关的临床参数之间的关联

IF3.1

2026-06-300

OA

Alpha-difluoromethylornithine suppresses angiogenesis via the FLI1-CLEC14A-VEGFC pathway in retinal endothelial cells

Biochemical and Biophysical Research Communications

IF2.2

2026-01-060

PRE

BALF editome profiling reveals A-to-I RNA editing associated with severity and complications of Mycoplasma pneumoniae pneumonia in children

IF3.1

2025-02-250

OAAI

RNA editing in response to COVID-19 vaccines: unveiling dynamic epigenetic regulation of host immunity

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-09-060

OAAI

Hippocampal adenosine-to-inosine RNA editing in sepsis: dynamic changes and influencing factors

脓毒症时海马腺苷-肌苷RNA编辑的动态变化及影响因素

BRAIN COMMUNICATIONS

IF4.5

2024-08-080

OAAI

Dynamic A-to-I RNA editing during acute neuroinflammation in sepsis-associated encephalopathy

FRONTIERS IN NEUROSCIENCE

IF3.2

2024-08-020

OAAI

Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota

NPJ BIOFILMS AND MICROBIOMES

IF9.2

2024-07-260

OAAI

Dysregulated RNA editing of EIF2AK2 in polycystic ovary syndrome: clinical relevance and functional implications

IF8.3

2024-06-100

OAAI

Ocular A-to-I RNA editing signatures associated with SARS-CoV-2 infection

IF3.7

2024-05-013

OAAI

Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing

IF6.9

2024-03-011

OAAI

Comparative Analysis of Molecular Landscape in Mouse Models and Patients Reveals Conserved Inflammation Pathways in Age-Related Macular Degeneration

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2024-01-042

OAAI

Transition of allele-specific DNA hydroxymethylation at regulatory loci is associated with phenotypic variation in monozygotic twins discordant for psychiatric disorders

IF8.3

2023-12-122

OAAI

Transcriptome analysis identification of A-to-I RNA editing in granulosa cells associated with PCOS

FRONTIERS IN ENDOCRINOLOGY

IF4.6

2023-07-215

OAAI

Epitranscriptomic investigation of myopia-associated RNA editing in the retina

FRONTIERS IN NEUROSCIENCE

IF3.2

2023-06-282

OAAI

Particles' distribution enhancing in aluminum-based composites produced by upward friction stir processing

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

IF6.4

2023-06-0712

OAAI

Gastric juice microbiota in pediatric chronic gastritis that clinically tested positive and negative for Helicobacter pylori

临床上检测幽门螺杆菌阳性和阴性的小儿慢性胃炎的胃液微生物群

FRONTIERS IN MICROBIOLOGY

IF4.5

2023-04-251

OAAI

Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-04-046

OAAI

Predicting IDH Mutation Status in Low-Grade Gliomas Based on Optimal Radiomic Features Combined with Multi-Sequence Magnetic Resonance Imaging

基于最优影像组学特征结合多序列磁共振成像预测低级别胶质瘤IDH突变状态

IF3.3

2022-11-3011

OAAI

研究方向

微生物-宿主互作及调控机制信号转导代谢途径表观遗传等多个层面，结合基因组学表观转录组学代谢组学蛋白质组学微生物组学系统生物学微生物-宿主互作的分子机制疾病诊断与防治的关键生物标志物功能性益生菌进行性和不可逆的神经退行性疾病肠道菌群通过肠道-菌群-脑轴在PD发病机制中的作用多组学方法青年期（ YA ）年龄相关肠道菌群组成结构和功能微生物互作网络拓扑结构灵长类肠道菌群动态变化遗传病的精准医学和基因编辑遗传病的致病机制解析与基因编辑技术研发生物信息学及分子生物学技术，实现对单基因病染色体病及复杂遗传病的精准诊断与个性化干预基于CRISPR-Cas9的技术基因治疗策略开发单碱基编辑基因编辑细胞与动物模型构建遗传病精准医学2024视网膜炎症年龄相关性黄斑变性

H 指数:14论文数:42被引数:495

H 指数:15论文数:38被引数:597

H 指数:7论文数:49被引数:284

H 指数:25论文数:99被引数:1,450

H 指数:12论文数:36被引数:351

H 指数:13论文数:49被引数:1,124

H 指数:0论文数:11被引数:0

H 指数:69论文数:644被引数:2.6万

H 指数:27论文数:100被引数:2,196

H 指数:53论文数:602被引数:1.1万