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Douglas B. Cines

University of Pennsylvania

86H指数
480论文数
3.3W被引数
收录论文 142
发表时间
Antiphospholipid syndrome (APS) is a platelet factor 4 (PF4)-centric immunothrombotic disorder抗磷脂综合征(APS)是一种以血小板因子4(PF4)为中心的免疫血栓性疾病
errBlood
IF23.1
err2026-07-02
err0
PREAI
errConroy O. Field; Amrita Sarkar; Khalil Bdeir; Hyunjun Kim; Santosh K. Yadav; Jenna Oberg; Guohua Zhou; Steven Jiang; Manas Gumedelli; Keith R. McCrae; Gowthami M. Arepally; Jerome Rollin; Yves Gruel; Thomas L. Ortel; M. Anna Kowalska; Douglas B. Cines; Kandace Gollomp; Lubica Rauova; Mortimer Poncz
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Primary versus Secondary Immune Thrombocytopenia (ITP): A Meeting Report from the 2023 McMaster ITP Summit
err2025-01-20
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errOAAI
errModi, Dimpy; Chowdhury, Saifur R.; Mahamad, Syed; Modi, Hayley; Cines, Douglas B.; Neunert, Cindy E.; Al-Samkari, Hanny; Cooper, Nichola; Moulis, Guillaume; Cunningham-Rundles, Charlotte; Liebman, Howard A.; Bussel, James B.; Breakey, Vicky R.; Nazy, Ishac; Arnold, Donald M.
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Complement activation as a biomarker for platelet-activating antibodies in heparin-induced thrombocytopenia补体激活作为肝素诱导血小板减少症中血小板激活抗体的生物标志物
err2024-12-01
err0
PREAI
errMyoung, Sooho S.; Francis, Samuel J.; Chen, Jonah; Lee, Grace; Rauova, Lubica; Poncz, Mortimer; Cines, Douglas B.; Kuchibhatla, Maragatha; Arepally, Gowthami M.
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Anti-Phospholipid Syndrome (APS) Antibody (Ab)-Induced Thrombosis Can be Blocked By Platelet Factor 4 (PF4)-Directed Abs: A Novel Therapeutic Approach for APS?抗磷脂综合征(APS)抗体(Ab)诱导的血栓可通过血小板因子4(PF4)定向抗体(Abs)阻断:这是APS的一种新型治疗策略?
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errSarkar, Amrita; Yadav, Santosh K.; Field, Conroy O.; Gollomp, Kandace; Mccrae, Keith R.; Ortel, Thomas L.; Gruel, Yves; Rollin, Jerome; Arepally, Gowthami M.; Rauova, Lubica; Cines, Douglas B.; Poncz, Mortimer
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PAI-1 deficiency drives pulmonary vascular smooth muscle remodeling and pulmonary hypertensionPAI-1缺乏导致肺血管平滑肌重塑和肺动脉高压
err2024-09-01
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errKudryashova, Tatiana V.; Zaitsev, Sergei V.; Jiang, Lifeng; Buckley, Benjamin J.; Mcguckin, Joshua P.; Goncharov, Dmitry; Zhyvylo, Iryna; Lin, Derek; Newcomb, Geoffrey; Piper, Bryce; Bogamuwa, Srimathi; Saiyed, Aisha; Teos, Leyla; Pena, Andressa; Ranson, Marie; Greenland, John R.; Wolters, Paul J.; Kelso, Michael J.; Poncz, Mortimer; Delisser, Horace M.; Cines, Douglas B.; Goncharova, Elena A.; Farkas, Laszlo; Stepanova, Victoria
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Packaging of supplemented urokinase into alpha granules of in vitro-grown megakaryocytes for targeted nascent clot lysis
err2024-07-12
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errOAAI
errPoncz, Mortimer; Zaitsev, Sergei, V; Ahn, Hyunsook; Kowalska, M. Anna; Bdeir, Khalil; Dergilev, Konstantin, V; Ivanciu, Lacramioara; Camire, Rodney M.; Cines, Douglas B.; Stepanova, Victoria
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Alpha-defensins: Risk factor for thrombosis in COVID-19 infection
err2024-05-01
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PREAI
errAbdeen, S.; Abu-Fanne, R.; Maraga, E.; Khurram, N.; Heyman, S. Samuel; Cines, D.; Higazi, A. Al-Roof
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Platelet factor 4 limits neutrophil extracellular trap- and cell-free DNA-induced thrombogenicity and endothelial injury血小板因子4限制中性粒细胞胞外陷阱和无细胞DNA诱导的血栓形成性和内皮损伤
err2023-11-22
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errOAAI
errNgo, Anh T. P.; Skidmore, Abigail; Oberg, Jenna; Yarovoi, Irene; Sarkar, Amrita; Levine, Nate; Bochenek, Veronica; Zhao, Guohua; Rauova, Lubica; Kowalska, M. Anna; Eckart, Kaitlyn; Mangalmurti, Nilam S.; Rux, Ann; Cines, Douglas B.; Poncz, Mortimer; Gollomp, Kandace
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Management of Primary Immune Thrombocytopenia in Pregnancy
err2023-08-10
err10
PREAI
errBussel, James B.; Hou, Ming; Cines, Douglas B.
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Treatment of thrombocytopenia and thrombosis in HIT in mice using deglycosylated KKO: a novel therapeutic?
err2023-07-28
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errSarkar, Amrita; Khandelwal, Sanjay; Koma, Gavin T.; Kim, Hyunjun; Gruel, Yves; Rollin, Jerome; Passam, Freda; Wool, Geoffrey D.; Arepally, Gowthami M.; Cines, Douglas B.; Rauova, Lubica; Poncz, Mortimer
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Fc modification to transform a pathogenic antibody into a potential therapeutic for thromboinflammatory disease
err2023-05-01
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errOAAI
errSarkar, Amrita; Gollomp, Kandace; Khandelwal, Sanjay; Arepally, Gowthami; Cines, Douglas B.; Kowalska, M. Anna; Rauova, Lubica; Poncz, Mortimer
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Modulation of ultralarge immune complexes in heparin- induced thrombocytopenia
err2023-03-01
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errOAAI
errCai, Zheng; Bdeir, Khalil; Yarovoi, Serge, V; Rauova, Lubica; Arepally, Gowthami M.; Khandelwal, Sanjay; Rollin, Jerome; Gruel, Yves; Zaitsev, Sergei; Poncz, Mortimer; Greene, Mark I.; Cines, Douglas B.
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Platelet factor 4 (CXCL4/PF4) upregulates matrix metalloproteinase-2 (MMP-2) in gingival fibroblasts
err2022-11-03
err5
errOAAI
errLe, Hoa T.; Golla, Kalyan; Karimi, Ryan; Hughes, Michael R.; Lakschevitz, Flavia; Cines, Douglas B.; Kowalska, M. Anna; Poncz, Mortimer; McNagny, Kelly M.; Hakkinen, Lari; Kim, Hugh
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Minimal role for the alternative pathway in complement activation by HIT immune complexes
err2022-11-01
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errOAAI
errBarnes, Ayiesha P.; Khandelwal, Sanjay; Sartoretto, Simone; Myoung, Sooho; Francis, Samuel J.; Lee, Grace M.; Rauova, Lubica; Cines, Douglas B.; Skare, Jon T.; Booth, Charles E., Jr.; Garcia, Brandon L.; Arepally, Gowthami M.
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Human neutrophil peptides 1-3 protect the murine urinary tract from uropathogenic Escherichia coli challenge
err2022-09-26
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errOAAI
errCanas, Jorge J.; Liang, Dong; Saxena, Vijay; Hooks, Jenaya; Arregui, Samuel W.; Gao, Hongyu; Liu, Yunlong; Kish, Danielle; Linn, Sarah C.; Bdeir, Khalil; Cines, Douglas B.; Fairchild, Robert L.; Spencer, John D.; Schwaderer, Andrew L.; Hains, David S.
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Erythrocytes identify complement activation in patients with COVID-19
err2021-08-01
err30
errOAAI
errLam, L. K. Metthew; Reilly, John P.; Rux, Ann H.; Murphy, Sophia J.; Kuri-Cervantes, Leticia; Weisman, Ariel R.; Ittner, Caroline A. G.; Pampena, M. Betina; Betts, Michael R.; Wherry, E. John; Song, Wen-Chao; Lambris, John D.; Meyer, Nuala J.; Cines, Douglas B.; Mangalmurti, Nilam S.
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COVID-19 vaccination and immune thrombocytopenia
err2021-06-09
err25
errOAAI
errPishko, Allyson M.; Bussel, James B.; Cines, Douglas B.
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Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells
err2021-04-15
err16
errOAAI
errDong, Yi Na; Hsu, Fu-Chun; Koziol-White, Cynthia J.; Stepanova, Victoria; Jude, Joseph; Gritsiuta, Andrei; Rue, Ryan; Mott, Rosalind; Coulter, Douglas A.; Panettieri, Reynold A., Jr.; Krymskaya, Vera P.; Takano, Hajime; Goncharova, Elena A.; Goncharov, Dmitry A.; Cines, Douglas B.; Lynch, David R.
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Thrombocytopenia following Pfizer and Moderna SARS-CoV-2 vaccination
err2021-03-09
err314
errOAAI
errLee, Eun-Ju; Cines, Douglas B.; Gernsheimer, Terry; Kessler, Craig; Michel, Marc; Tarantino, Michael D.; Semple, John W.; Arnold, Donald M.; Godeau, Bertrand; Lambert, Michele P.; Bussel, James B.
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