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Yunjiang Zhou

China Pharmaceutical University

H指数:17

被引数:908

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Structure-Based Discovery of the First Inhibitor Targeting the Talin2-β-integrin Interaction with Potent In Vivo Antitumor Activity in Breast Cancer Models

基于结构的首次发现靶向Talin2-β-整合素相互作用且在乳腺癌模型中具有强效体内抗肿瘤活性的抑制剂

Journal of Medicinal Chemistry

IF6.8

2026-04-220

PRE

The incorporation of acetylated LAP-TGF-β1 proteins into exosomes promotes TNBC cell dissemination in lung micro-metastasis

MOLECULAR CANCER

IF33.9

2024-04-251

OAAI

Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition

MOLECULAR CANCER RESEARCH

IF4.7

2024-02-216

PRE

FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-02-0135

OAAI

Highly Potent, Selective, Biostable, and Cell-Permeable Cyclic D-Peptide for Dual-Targeting Therapy of Lung Cancer

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2022-04-1331

PRE

A Supramolecular Nanomedicine Based on Bendamustine and MDM2-Targeted D-peptide Inhibitor for Breast Cancer Therapy

基于苯达莫司汀和MDM2-Targeted D-肽抑制剂的超分子纳米药物用于乳腺癌治疗

ADVANCED HEALTHCARE MATERIALS

IF9.6

2021-09-238

PREAI

An NRP1/MDM2-Targeted D-Peptide Supramolecular Nanomedicine for High-Efficacy and Low-Toxic Liver Cancer Therapy

ADVANCED HEALTHCARE MATERIALS

IF9.6

2021-03-0923

PREAI

Flumethasone enhances the efficacy of chemotherapeutic drugs in lung cancer by inhibiting Nrf2 signaling pathway

IF10.1

2020-04-0120

PREAI

HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling

HEATR1缺陷通过上调Nrf2信号促进胰腺癌增殖和吉西他滨耐药

IF11.9

2020-01-0129

OAAI

Discovery of a Potent PLK1-PBD Small-Molecule Inhibitor as an Anticancer Drug Candidate through Structure-Based Design

IF4.6

2019-11-284

OAAI

Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking and Biological Evaluation for Identification of Potential Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors

基于结构的药效团建模，虚拟筛选，分子对接和生物学评估，以鉴定潜在的聚 (ADP-核糖) 聚合酶-1 (PARP-1) 抑制剂

IF4.6

2019-11-2228

OAAI

A Redox-Triggered Bispecific Supramolecular Nanomedicine Based on Peptide Self-Assembly for High-Efficacy and Low-Toxic Cancer Therapy

ADVANCED FUNCTIONAL MATERIALS

IF19

2019-10-3041

PREAI

Structure-Based Pharmacophore Design and Virtual Screening for Novel Tubulin Inhibitors with Potential Anticancer Activity

IF4.6

2019-09-0118

OAAI

Absent in melanoma 2 suppresses epithelial-mesenchymal transition via Akt and inflammasome pathways in human colorectal cancer cells

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2019-06-189

PREAI

Digoxin sensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine via inhibiting Nrf2 signaling pathway

IF11.9

2019-04-0159

OAAI