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H

Heikki Joensuu

orion corporation
H指数:127
被引数:7.3万

个人简介

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荣誉奖项

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Clinically relevant endpoints and quality-of-life outcomes with darolutamide in patients with metastatic hormone-sensitive prostate cancer: analyses of the phase III ARASENS trial

达罗鲁胺在转移性激素敏感前列腺癌患者中的临床相关终点和生活质量结局：III期ARASENS试验的分析

European Journal of Cancer
IF7.1
2026-06-120
PRE
Karim Fizazi; Matthew R. Smith; Maha Hussain; Fred Saad; Cora N. Sternberg; E. David Crawford; Jeanny B. Aragon-Ching; Martin Schostak; Ronald Tutrone; Alicia K. Morgans; Daniel Sentana-Lledo; Heikki Joensuu; Ateesha F. Mohamed; Natasha Littleton; Shankar Srinivasan; Yvonne Buttkewitz; Rui Li; Iris Kuss; Bertrand Tombal
Safety, pharmacokinetics, pharmacodynamics, and antitumor activity of cergutuzumab amunaleukin: a phase I study in patients with advanced and/or metastatic solid tumors

塞格图单抗阿穆纳鲁金的安全性与药代动力学、药效学及抗肿瘤活性：一项针对晚期和/或转移性实体瘤患者的I期研究

ESMO Open
IF8.3
2026-05-130
OAAI
U. Lassen; E.M.J. van Brummelen; I. Melero; E. Angevin; H. Joensuu; N.H. Segal; M. Mau-Sørensen; N. Steeghs; M.E. Rodríguez-Ruiz; K. Homicsko; J. Tabernero; M. Cañamero; D. Dejardin; C. Habigt; E. Rossmann; E. Guarin; G. Babitzki; H.E.S. Baumann; A.P. Silva; C. Adessi
Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis (vol. 124, pg. 1069, 2014)

p53突变相关的肌球蛋白-X上调促进乳腺癌侵袭和转移（vol. 124, pg. 1069, 2014）

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2025-12-010
PRE
Arjonen, Antti; Kaukonen, Riina; Mattila, Elina; Rouhi, Pegah; Hognas, Gunilla; Sihto, Harri; Miller, Bryan W.; Morton, Jennifer P.; Bucher, Elmar; Taimen, Pekka; Virtakoivu, Reetta; Cao, Yihai; Sansom, Owen J.; Joensuu, Heikki; Ivaska, Johanna
Darolutamide plus androgen-deprivation therapy in high-risk biochemical recurrence of prostate cancer (ARASTEP)
FUTURE ONCOLOGY
IF2.6
2025-11-010
PRE
Morgans, Alicia K.; Chehrazi-Raffle, Alex; Niazi, Tamim; Shore, Neal D.; Ross, Ashley E.; Roder, Andreas; Gomes, Andrea Juliana; Supiot, Stephane; Barthelemy, Philippe; Hatano, Koji; Ruiz, Carmen Belen Congregado; Yoshida, Soichiro; Herrera-Imbroda, Bernardo; Gratton, Matthieu; Gschwend, Jurgen E.; Hope, Thomas A.; Joensuu, Heikki; Kuss, Iris; Le Berre, Marie-Aude; Dimova-Dobreva, Miryana; Fizazi, Karim
p95HER2, a truncated form of the HER2 oncoprotein, drives an immunosuppressive program in HER2+ breast cancer that limits trastuzumab deruxtecan efficacy

p95HER2，HER2癌蛋白的一种截断形式，在HER2+乳腺癌中驱动一种免疫抑制程序，限制了T-DXd（trastuzumab deruxtecan）的疗效。

Nature Cancer
IF28.5
2025-06-270
PRE
Dong Hu; Xiaoshuang Lyu; Zheqi Li; Prasanna Ekambaram; Anushka Dongre; Tanner Freeman; Marion Joy; Jennifer M. Atkinson; Daniel D. Brown; Zongyou Cai; Neil M. Carleton; Hannah E. Crentsil; John Little; Felicia Kemp; Linda R. Klei; Maria Beecher; Jeff Sperinde; Weidong Huang; Heikki Joensuu; Ashok Srinivasan; Katherine L. Pogue-Geile; Ying Wang; Huichen Feng; Lisa D. Eli; Alshad S. Lalani; Jian Zou; George C. Tseng; Tullia C. Bruno; Adrian V. Lee; Steffi Oesterreich; Norman Wolmark; Carmen J. Allegra; Samuel A. Jacobs; Linda M. McAllister-Lucas; Peter C. Lucas
PTPN9 regulates HER3 phosphorylation during trastuzumab treatment and loss of PTPN9 is a potential biomarker for trastuzumab resistance in HER2 positive breast cancer
CANCER COMMUNICATIONS
IF24.9
2024-11-240
PRE
Azad, Abul; Arshad, Maryam; Generali, Daniele; Feldinger, Katharina; Gijsen, Merel; Strina, Carla; Cappelletti, Mariarosa; Andreis, Daniele; Leek, Russell; Haider, Syed; Kellokumpu-Lehtinen, Pirkko-Liisa; Roxanis, Ioannis; Harris, Adrian Llewellyn; Shaaban, Abeer Mahmoud; Joensuu, Heikki; Kong, Anthony
Long-Term Outcomes of Adjuvant Trastuzumab for 9 Weeks or 1 Year for ERBB2-Positive Breast Cancer A Secondary Analysis of the SOLD Randomized Clinical Trial
JAMA NETWORK OPEN
IF9.7
2024-08-261
OA
Joensuu, Heikki; Fraser, Judith; Wildiers, Hans; Huovinen, Riikka; Auvinen, Paeivi; Utriainen, Meri; Villman, Kenneth K.; Halonen, Paivi; Granstam-Bjorneklett, Helena; Tanner, Minna; Sailas, Liisa; Turpeenniemi-Hujanen, Taina; Yachnin, Jeffrey; Huttunen, Teppo; Neven, Patrick; Canney, Peter; Harvey, Vernon J.; Kellokumpu-Lehtinen, Pirkko-Liisa; Lindman, Henrik
The spatially resolved single-cell atlas of the tumor immune architecture revealed the central role of IFN-alpha and plasmacytoid dendritic cells in triple-negative breast cancer in the Mayo Clinic cohort and FinXX trial
CANCER RESEARCH
IF16.6
2024-05-020
PRE
Chumsri, Saranya; Liu, Yi; Ma, Yaohua; Carter, Jodi; Gregory, Mark; Church, Sarah; Reeves, Jason; Brauer, Heather Ann; Warren, Sarah; Joensuu, Heikki; Perez, Edith; Leon-Ferre, Roberto; Hillman, David; Boughey, Judy; Ingle, James; Kalari, Krishna; Couch, Fergus; Goetz, Matthew; Knutson, Keith; Thompson, E.
Safety and tolerability of long-term treatment with darolutamide in patients with metastatic castration-resistant prostate cancer
PROSTATE CANCER AND PROSTATIC DISEASES
IF5.8
2023-10-260
OAAI
Jones, Robert Hugh; Fizazi, Karim; James, Nicholas D.; Tammela, Teuvo L.; Matsubara, Nobuaki; Priou, Frank; Beuzeboc, Philippe; Lesimple, Thierry; Bono, Petri; Kataja, Vesa; Garcia, Jorge A.; Protheroe, Andrew; Shore, Neal; Aspegren, John; Joensuu, Heikki; Kuss, Iris; Fiala-Buskies, Sabine; Vjaters, Egils
Genome-Wide Association Study Identifies 4 Novel Risk Loci for Small Intestinal Neuroendocrine Tumors Including a Missense Mutation in LGR5

全基因组关联研究确定了小肠神经内分泌肿瘤的4个新风险位点，包括LGR5中的错义突变

GASTROENTEROLOGY
IF25.1
2023-10-012
OA
Giri, Anil K.; Aavikko, Mervi; Wartiovaara, Linnea; Lemmetyinen, Toni; Karjalainen, Juha; Mehtonen, Juha; Palin, Kimmo; Valimaki, Niko; Tamlander, Max; Saikkonen, Riikka; Karhu, Auli; Morgunova, Ekaterina; Sun, Benjamin; Runz, Heiko; Palta, Priit; Luo, Shuang; Joensuu, Heikki; Makela, Tomi P.; Kostiainen, Iiro; Schalin-Jantti, Camilla; FinnGen; Palotie, Aarno; Aaltonen, Lauri A.; Ollila, Saara; Daly, Mark J.
Distinct spatial immune microlandscapes are independently associated with outcomes in triple-negative breast cancer
NATURE COMMUNICATIONS
IF15.7
2023-04-1815
OAAI
Carter, Jodi M.; Chumsri, Saranya; Hinerfeld, Douglas A.; Ma, Yaohua; Wang, Xue; Zahrieh, David; Hillman, David W.; Tenner, Kathleen S.; Kachergus, Jennifer M.; Brauer, Heather Ann; Warren, Sarah E.; Henderson, David; Shi, Ji; Liu, Yi; Joensuu, Heikki; Lindman, Henrik; Leon-Ferre, Roberto A.; Boughey, Judy C.; Liu, Minetta C.; Ingle, James N.; Kalari, Krishna R.; Couch, Fergus J.; Knutson, Keith L.; Goetz, Matthew P.; Perez, Edith A.; Thompson, E. Aubrey

研究方向

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Harri Sihto
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P
Petri Bono
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Peter Reichardt
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Jorma Isola
H 指数:92论文数:395被引数:3.1万
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Sebastian Bauer
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Peter Hohenberger
H 指数:85论文数:733被引数:3.3万
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Jean‐Yves Blay
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Johan Lundin
H 指数:56论文数:266被引数:1.1万
P
Pirkko‐Liisa Kellokumpu‐Lehtinen
H 指数:42论文数:281被引数:9,196
K
Kirsten Sundby Hall
H 指数:48论文数:196被引数:1.5万