Keiichi Higuchi - Publications, H-index & Citations

Keiichi Higuchi

1220-1 biimata

46H指数

236论文数

8.4K被引数

收录论文 75

发表时间

Effects of lifetime supplementation with ubiquinol 10 on the lifespan and progression of aging in female C57BL/6 mice 辅酶Q10氢醌10终生补充对雌性C57BL/6小鼠寿命及衰老进程的影响

Experimental Gerontology

IF4.3

2025-10-11

OAAI

Yuichi Igarashi; Sakiko Hamada; Jin Dai; Masayuki Mori; Hiroki Miyahara; Jinko Sawashita; Keiichi Higuchi

Cryo-EM observation of AA amyloid fibrils in mouse model of systemic AApoAII amyloidosis 小鼠系统性AApoAII淀粉样变性模型的AA淀粉样纤维的冷冻电镜观察

Journal of Molecular Biology

IF4.5

2025-09-11

PREAI

Giada Andreotti; Keichii Higuchi; Matthias Schmidt; Marcus Fändrich

Macrophages in the reticuloendothelial system inhibit early induction stages of mouse apolipoprotein A-II amyloidosis

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2022-12-10

PREAI

Miyahara, Hiroki; Dai, Jian; Li, Ying; Cui, Xiaoran; Takeuchi, Hibiki; Hachiya, Naomi; Kametani, Fuyuki; Yazaki, Masahide; Mori, Masayuki; Higuchi, Keiichi

Exercise suppresses mouse systemic AApoAII amyloidosis through enhancement of the p38 MAPK signaling pathway

DISEASE MODELS & MECHANISMS

IF3.3

2022-03-21

OAAI

Cui, Xiaoran; Sawashita, Jinko; Dai, Jian; Liu, Chang; Igarashi, Yuichi; Mori, Masayuki; Miyahara, Hiroki; Higuchi, Keiichi

Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpoxnct mice

EXPERIMENTAL EYE RESEARCH

IF2.7

2022-02-01

OAAI

Liu, Chang; Miyahara, Hiroki; Dai, Jian; Cui, Xiaoran; Li, Ying; Kang, Xiaojing; Higuchi, Keiichi; Mori, Masayuki

Glavonoid-rich oil supplementation reduces stearoyl-coenzyme A desaturase 1 expression and improves systemic metabolism in diabetic, obese KK-Ay mice

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2021-08-01

OAAI

Igarashi, Yuichi; Iida, Shiho; Dai, Jian; Huo, Jia; Cui, Xiaoran; Sawashita, Jinko; Mori, Masayuki; Miyahara, Hiroki; Higuchi, Keiichi

Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway

ELIFE

IF0

2021-01-26

OAAI

Dai, Jian; Li, Ying; Kametani, Fuyuki; Cui, Xiaoran; Igarashi, Yuichi; Huo, Jia; Miyahara, Hiroki; Mori, Masayuki; Higuchi, Keiichi

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2020-09-02

OAAI

Mizuno, Hiroki; Hoshino, Junichi; So, Masatomo; Kogure, Yuta; Fujii, Takeshi; Ubara, Yoshifumi; Takaichi, Kenmei; Nakaniwa, Tetsuko; Tanaka, Hideaki; Kurisu, Genji; Kametani, Fuyuki; Nakagawa, Mayuko; Yoshinaga, Tsuneaki; Sekijima, Yoshiki; Higuchi, Keiichi; Goto, Yuji; Yazaki, Masahide

Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure

SCIENTIFIC REPORTS

IF3.9

2018-04-04

OAAI

Yang, Mu; Liu, Yingye; Dai, Jian; Li, Lin; Ding, Xin; Xu, Zhe; Mori, Masayuki; Miyahara, Hiroki; Sawashita, Jinko; Higuchi, Keiichi

Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition

SCIENTIFIC REPORTS

IF3.9

2017-08-15

OAAI

Xu, Zhe; Huo, Jia; Ding, Xin; Yang, Mu; Li, Lin; Dai, Jian; Hosoe, Kazunori; Kubo, Hiroshi; Mori, Masayuki; Higuchi, Keiichi; Sawashita, Jinko

Apolipoprotein A-II accelerates reactive AA amyloidosis

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2017-04-22

PREAI

Yang, Mu; Liu, Yingye; Li, Lin; Miyahara, Hiroki; Ding, Xin; Dai, Jian; Sawashita, Jinko; Mori, Masayuki; Higuchi, Keiichi

Caloric restriction prevents the progression of murine AApoAII amyloidosis

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2017-04-22

PREAI

Sawashita, Jinko; Li, Lin; Liu, Yingye; Ding, Xin; Yang, Mu; Xu, Zhe; Higuchi, Keiichi

Marked biochemical difference in amyloid proportion between intra- and extraocular tissues in a liver-transplanted patient with hereditary ATTR amyloidosis

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2017-01-13

OAAI

Yoshinaga, Tsuneaki; Yazaki, Masahide; Kametani, Fuyuki; Sekijima, Yoshiki; Iesato, Yasuhiro; Miyahara, Teruyoshi; Tsuchiya-Suzuki, Ayako; Sano, Kenji; Higuchi, Keiichi; Ikeda, Shu-ichi

The first pure form of Ostertag-type amyloidosis in Japan: a sporadic case of hereditary fibrinogen Aα-chain amyloidosis associated with a novel frameshift variant

AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

IF7.4

2015-05-27

PREAI

Yazaki, Masahide; Yoshinaga, Tsuneaki; Sekijima, Yoshiki; Nishio, Saori; Kanizawa, Yuji; Kametani, Fuyuki; Miyashita, Kana; Hachiya, Naomi; Higuchi, Keiichi; Ikeda, Shu-ichi

SENESCENCE-ACCELERATED MOUSE (SAM) - A NOVEL MURINE MODEL OF ACCELERATED SENESCENCE

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

IF4.5

2015-04-27

351

PREAI

TAKEDA, T; HOSOKAWA, M; HIGUCHI, K

Extracellular deposition of mouse senile AApoAII amyloid fibrils induced different unfolded protein responses in the liver, kidney, and heart

LABORATORY INVESTIGATION

IF4.2

2015-03-01

OAAI

Luo, Hongmin; Sawashita, Jinko; Tian, Geng; Liu, Yingye; Li, Lin; Ding, Xin; Xu, Zhe; Yang, Mu; Miyahara, Hiroki; Mori, Masayuki; Qian, Jinze; Wang, Yaoyong; Higuchi, Keiichi

The factors affecting adherence to a long-term interval walking training program in middle-aged and older people

JOURNAL OF APPLIED PHYSIOLOGY

IF3.3

2015-03-01

PREAI

Masuki, Shizue; Mori, Masayuki; Tabara, Yasuharu; Sakurai, Akihiro; Hashimoto, Shigenari; Morikawa, Mayuko; Miyagawa, Ken; Sumiyoshi, Eri; Miki, Tetsuro; Higuchi, Keiichi; Nose, Hiroshi

C-terminal sequence of amyloid-resistant type F apolipoprotein A-II inhibits amyloid fibril formation of apolipoprotein A-II in mice 抗淀粉样蛋白的F型载脂蛋白A-II的C端序列抑制小鼠载脂蛋白A-II的淀粉样蛋白原纤维形成

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-02-09

OAAI

Sawashita, Jinko; Zhang, Beiru; Hasegawa, Kazuhiro; Mori, Masayuki; Naiki, Hironobu; Kametani, Fuyuki; Higuchi, Keiichi

The Toxicity Mechanisms of Action of Aβ25-35 in Isolated Rat Cardiac Myocytes

MOLECULES

IF4.6

2014-08-13

OAAI

Zhang, Beiru; Bian, Xiaohui; He, Ping; Fu, Xiaoying; Higuchi, Keiichi; Yang, Xu; Li, Detian

Ubiquinol-10 Supplementation Activates Mitochondria Functions to Decelerate Senescence in Senescence-Accelerated Mice

ANTIOXIDANTS & REDOX SIGNALING

IF6.1

2014-06-01

OAAI

Tian, Geng; Sawashita, Jinko; Kubo, Hiroshi; Nishio, Shin-ya; Hashimoto, Shigenari; Suzuki, Nobuyoshi; Yoshimura, Hidekane; Tsuruoka, Mineko; Wang, Yaoyong; Liu, Yingye; Luo, Hongming; Xu, Zhe; Mori, Masayuki; Kitano, Mitsuaki; Hosoe, Kazunori; Takeda, Toshio; Usami, Shin-ichi; Higuchi, Keiichi

研究方向