Ivone Carvalho

universidade de sao paulo

H指数:31

被引数:4,825

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Design, Synthesis, and Evaluation of Naphthyl Pyrazino-Pyrido-Pyrimidinones Targeting the Phosphoinositide 3-Kinase/Alpha-Serine/Protein Kinase B/Mammalian Target of Rapamycin Pathway

萘基嘧啶并吡啶-吡嗪酮的设计、合成及对磷脂酰肌醇3-激酶/α-丝氨酸/蛋白激酶B/雷帕霉素靶蛋白通路靶向评价

ChemistryOpen

IF3.1

2026-02-010

OAAI

Synthesis and Biological Evaluation of 4-(4-Nitrophenyl)-1H-1,2,3-triazole Derivatives as Antitrypanosomal Agents

4-(4-硝基苯基)-1H-1,2,3-三唑衍生物的合成与生物活性评价：作为抗锥虫病药物的研究

ACS OMEGA

IF4.3

2025-05-130

Novel donepezil-tacrine hybrid (TAHB3) induces neurodifferentiation, neuroprotective effects, and activates the PI3K/AKT pathway on PC12 cells

新型多奈哌齐-他克林杂合物（TAHB3）可诱导PC12细胞的神经分化、产生神经保护作用，并激活PI3K/AKT信号通路。

JOURNAL OF ALZHEIMERS DISEASE REPORTS

IF2.8

2025-01-130

Editorial: Carbohydrate-Based Molecules in Medicinal Chemistry

FRONTIERS IN CHEMISTRY

IF4.2

2021-03-051

OAAI

Non-cytotoxic 1,2,3-triazole tethered fused heterocyclic ring derivatives display Tax protein inhibition and impair HTLV-1 infected cells

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2020-11-012

OAAI

Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway

JOURNAL OF ALZHEIMERS DISEASE

IF3.1

2020-10-273

PREAI

Antitumour Anthracyclines: Progress and Perspectives

CHEMMEDCHEM

IF3.4

2020-05-07123

PREAI

Synthesis and Evaluation of [18F]FEtLos and [18F]AMBF3Los as Novel 18F-Labelled Losartan Derivatives for Molecular Imaging of Angiotensin II Type 1 Receptors

MOLECULES

IF4.6

2020-04-185

OAAI

1,2,3-Triazole tethered 2-mercaptobenzimidazole derivatives: design, synthesis and molecular assessment toward C6 glioma cell line

FUTURE MEDICINAL CHEMISTRY

IF3.4

2020-03-2011

PREAI

Copper Reactivity Can Be Tuned to Catalyze the Stereoselective Synthesis of 2-Deoxyglycosides from Glycals

ORGANIC LETTERS

IF5

2020-02-1922

OAAI

Protozoan Parasites Glycosylphosphatidylinositol Anchors: Structures, Functions and Trends for Drug Discovery

CURRENT MEDICINAL CHEMISTRY

IF3.5

2019-10-109

PRE

Potential Triazole-based Molecules for the Treatment of Neglected Diseases

CURRENT MEDICINAL CHEMISTRY

IF3.5

2019-10-1015

PRE

Iminosugars: Effects of Stereochemistry, Ring Size, and N-Substituents on Glucosidase Activities

PHARMACEUTICALS

IF4.8

2019-07-1227

OAAI

Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease

阿尔茨海默氏病中丁酰胆碱酯酶的高效和选择性aryl-1，2，3-三唑基苄基哌啶抑制剂

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2019-03-0130

PREAI

Beyond the 'Lock and Key Paradigm: Targeting Lipid Rafts to Induce the Selective Apoptosis of Cancer Cells

CURRENT MEDICINAL CHEMISTRY

IF3.5

2018-05-2214

PREAI

Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-02-0123

PREAI

Synthesis and 2D-QSAR studies of neolignan-based diaryltetrahydrofuran and -furan analogues with remarkable activity against Trypanosoma cruzi and assessment of the trypanothione reductase activity

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-11-0121

PREAI

Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2017-11-0116

PREAI

Benzoic Acid Derivatives with Trypanocidal Activity: Enzymatic Analysis and Molecular Docking Studies toward Trans-Sialidase

MOLECULES

IF4.6

2017-10-3020

OAAI

From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-10-0144

OAAI

Ivone Carvalho

个人简介

教育背景

工作经历

荣誉奖项

研究方向