logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
J

John F. Hancock

University of Texas Health Science Center

84H指数
283论文数
2.7W被引数
收录论文 145
发表时间
logo
Glycosphingolipids regulate phosphatidylserine transport machinery that operates at ER-PM contact sites鞘糖脂调控在ER-PM接触位点运作的磷脂酰丝氨酸转运机制
errNature Communications
IF15.7
err2026-06-12
err0
errOAAI
errRitchel Gannaban; Sher Ali; Wei Chen; Melanie Nguyen; Li Lai; Travis I. Moore; Yubin Zhou; John F. Hancock; Junchen Liu
err分享
err收藏
DIRAS3-derived cyclic peptides disrupt KRAS-RAF interaction and KRAS nanoclustering, suppressing KRAS-driven pancreatic and ovarian tumorsDIRAS3衍生的环状肽破坏KRAS-RAF相互作用和KRAS纳米聚集，抑制KRAS驱动的胰腺和卵巢肿瘤
erriScience
IF4.1
err2025-10-04
err0
errOAAI
errJoshua P. Gray; Gamze Bildik; Ha-Neul Kim; Margie N. Sutton; Jing Wang; Amarachi O. Osuji; Nefeli Batistatou; Hailing Yang; Weiqun Mao; Zhi Tan; Geneviève M.C. Gasmi-Seabrook; Junchen Liu; John F. Hancock; Christopher B. Marshall; Joshua A. Kritzer; Mitsuhiko Ikura; Robert C. Bast; Steven W. Millward; Zhen Lu
err分享
err收藏
Terraforming the KRAS lipid landscape改造KRAS脂质景观
errNature Chemical Biology
IF13.7
err2025-09-15
err0
PREAI
errYong Zhou; John F. Hancock
err分享
err收藏
MTMR regulates KRAS function by controlling plasma membrane levels of phospholipidsMTMR通过控制细胞膜中磷脂的水平来调节KRAS的功能。
errJOURNAL OF CELL BIOLOGY
IF6.4
err2025-05-02
err0
PREAI
errLange, Taylor E.; Naji, Ali; van der Hoeven, Ransome; Liang, Hong; Zhou, Yong; Hammond, Gerald R. V.; Hancock, John F.; Cho, Kwang-jin
err分享
err收藏
Differential Lipid Binding Specificities of RAP1A and RAP1B are Encoded by the Amino Acid Sequence of the Membrane Anchors
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-07-13
err1
errOAAI
errAraya, Mussie K.; Chen, Wei; Ke, Yuepeng; Zhou, Yubin; Gorfe, Alemayehu A.; Hancock, John F.; Liu, Junchen
err分享
err收藏
DIRAS3 inhibits oncogenic RAS signaling and RAS-dependent cell growth driven by prevalent KRAS hot spot mutations
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errBildik, Gamze; Liu, Junchen; Mao, Weiqun; Yang, Hailing; Hancock, John F.; Bast, Robert C.; Lu, Zhen
err分享
err收藏
Direct Modulators of K-Ras-Membrane Interactions
errACS CHEMICAL BIOLOGY
IF3.8
err2023-08-14
err7
errOAAI
errMorstein, Johannes; Shrestha, Rebika; Van, Que N.; Lopez, Cesar A.; Arora, Neha; Tonelli, Marco; Liang, Hong; Chen, De; Zhou, Yong; Hancock, John F.; Stephen, Andrew G.; Turbyville, Thomas J.; Shokat, Kevan M.
err分享
err收藏
Consensus on the RAS dimerization hypothesis: Strong evidence for lipid-mediated clustering but not for G-domain-mediated interactions关于RAS二聚化假说的共识: 脂质介导的聚类而不是G域介导的相互作用的有力证据
errMOLECULAR CELL
IF16.6
err2023-04-01
err23
errOAAI
errSimanshu, Dhirendra K.; Philips, Mark R.; Hancock, John F.
err分享
err收藏
14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err137
errOAAI
errRoy, S; McPherson, RA; Apolloni, A; Yan, J; Lane, A; Clyde-Smith, J; Hancock, JF
err分享
err收藏
H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err139
errOAAI
errRoy, S; Wyse, B; Hancock, JF
err分享
err收藏
Individual palmitoyl residues serve distinct roles in H-ras trafficking, microlocalization, and signaling
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err208
errOAAI
errRoy, S; Plowman, S; Rotblat, B; Prior, IA; Muncke, C; Grainger, S; Parton, RG; Henis, YI; Kloog, Y; Hancock, JF
err分享
err收藏
Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err189
errOAAI
errNicolau, DV; Burrage, K; Parton, RG; Hancock, JF
err分享
err收藏
H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err416
errOAAI
errApolloni, A; Prior, IA; Lindsay, M; Parton, RG; Hancock, JF
err分享
err收藏
Three separable domains regulate GTP-dependent association of H-ras with the plasma membrane
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err152
errOAAI
errRotblat, B; Prior, IA; Muncke, C; Parton, RG; Kloog, Y; Henis, YI; Hancock, JF
err分享
err收藏
Electrostatic interactions positively regulate K-ras nanocluster formation and function静电相互作用正向调节k-ras纳米团簇的形成和功能
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err103
errOAAI
errPlowman, Sarah J.; Ariotti, Nicholas; Goodall, Andrew; Parton, Robert G.; Hancock, John F.
err分享
err收藏
Epidermal Growth Factor Receptor Activation Remodels the Plasma Membrane Lipid Environment To Induce Nanocluster Formation表皮生长因子受体激活重塑质膜脂质环境以诱导纳米簇形成
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err87
errOAAI
errAriotti, Nicholas; Liang, Hong; Xu, Yufei; Zhang, Yueqiang; Yonekubo, Yoshiya; Inder, Kerry; Du, Guangwei; Parton, Robert G.; Hancock, John F.; Plowman, Sarah J.
err分享
err收藏
Signal Integration by Lipid-Mediated Spatial Cross Talk between Ras NanoclustersRas纳米簇之间脂质介导的空间串扰的信号整合
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err118
errOAAI
errZhou, Yong; Liang, Hong; Rodkey, Travis; Ariotti, Nicholas; Parton, Robert G.; Hancock, John F.
err分享
err收藏
Temporal Production of the Signaling Lipid Phosphatidic Acid by Phospholipase D2 Determines the Output of Extracellular Signal-Regulated Kinase Signaling in Cancer Cells磷脂酶D2产生的信号脂质磷脂酸的时间决定了癌细胞中细胞外信号调节激酶信号的输出
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err100
errOAAI
errZhang, Feng; Wang, Ziqing; Lu, Maryia; Yonekubo, Yoshiya; Liang, Xiao; Zhang, Yueqiang; Wu, Ping; Zhou, Yong; Grinstein, Sergio; Hancock, John F.; Du, Guangwei
err分享
err收藏
Fendiline Inhibits K-Ras Plasma Membrane Localization and Blocks K-Ras Signal TransmissionFendiline抑制k-ras质膜定位并阻断k-ras信号传输
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err96
errOAAI
errvan der Hoeven, Dharini; Cho, Kwang-jin; Ma, Xiaoping; Chigurupati, Sravanthi; Parton, Robert G.; Hancock, John F.
err分享
err收藏
Therapeutic Levels of the Hydroxmethylglutaryl-Coenzyme A Reductase Inhibitor Lovastatin Activate Ras Signaling via Phospholipase D2羟甲基戊二酰辅酶a还原酶抑制剂洛伐他汀的治疗水平通过磷脂酶D2激活Ras信号
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err35
errOAAI
errCho, Kwang-jin; Hill, Michelle M.; Chigurupati, Sravanthi; Du, Guangwei; Parton, Robert G.; Hancock, John F.
err分享
err收藏

研究方向

暂无研究方向
合作学者
合作期刊
S
Steven P. Gygi
H 指数: 195 · 论文数: 1.0K
A
Anil K. Sood
H 指数: 174 · 论文数: 3.3K
M
Mien‐Chie Hung
H 指数: 163 · 论文数: 1.5K
I
Ignacio I. Wistuba
H 指数: 153 · 论文数: 2.8K
R
Robert G. Parton
H 指数: 149 · 论文数: 705
查看更多