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Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial Abel, Melissa L.; Takahashi, Nobuyuki; Peer, Cody; Redon, Christophe E.; Nichols, Samantha; Vilimas, Rasa; Lee, Min -Jung; Lee, Sunmin; Shelat, Meenakshi; Kattappuram, Robbie; Sciuto, Linda; Pinkiert, Danielle; Graham, Chante; Butcher, Donna; Karim, Baktiar; Sharma, Ajit Kumar; Malin, Justin; Kumar, Rajesh; Schultz, Christopher W.; Goyal, Shubhank; del Rivero, Jaydira; Krishnamurthy, Manan; Upadhyay, Deep; Schroeder, Brett; Sissung, Tristan; Tyagi, Manoj; Kim, Jung; Pommier, Yves; Aladjem, Mirit; Raffeld, Mark; Douglas, William; Trepel, Jane; Xi, Liqiang; Desai, Parth; Thomas, Anish 分享 收藏
Targeting replication stress and chemotherapy resistance with a combination of sacituzumab govitecan and berzosertib: A phase I clinical trial Abel, Melissa L.; Takahashi, Nobukyuki; Desai, Parth; Peer, Cody; Redon, Christophe; Nichols, Samantha; Vilimas, Rasa; Lee, Min-Jung; Lee, Sunmin; Sciuto, Linda; Pinkiert, Danielle; Shelat, Meenakshi; Graham, Chante; Steinberg, Seth; Figg, William D.; Aladjem, Mirit; Trepel, Jane; Pommier, Yves; Thomas, Anish 分享 收藏
Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies Zhang, Mary; Hong, Julie A.; Kunst, Tricia F.; Bond, Colleen D.; Kenney, Cara M.; Warga, Cheryl L.; Yeray, Javier; Lee, Min-Jung; Yuno, Akira; Lee, Sunmin; Miettinen, Markku; Ripley, R. Taylor; Hoang, Chuong D.; Gnjatic, Sacha; Trepel, Jane B.; Schrump, David S. 分享 收藏
Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy Hellmann, Matthew D.; Janne, Pasi A.; Opyrchal, Mateusz; Hafez, Navid; Raez, Luis E.; Gabrilovich, Dmitry, I; Wang, Fang; Trepel, Jane B.; Lee, Min-Jung; Yuno, Akira; Lee, Sunmin; Brouwer, Susan; Sankoh, Serap; Wang, Lei; Tamang, David; Schmidt, Emmett, V; Meyers, Michael L.; Ramalingam, Suresh S.; Shum, Elaine; Ordentlich, Peter 分享 收藏
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In small cell lung cancer patients treated with RRx-001, a downregulator of CD47, decreased expression of PD-L1 on circulating tumor cells significantly correlates with clinical benefit 在接受RRx-001治疗的小细胞肺癌患者中，CD47的下调，循环肿瘤细胞上PD-L1的表达降低与临床益处显着相关 Tomita, Yusuke; Oronsky, Bryan; Abrouk, Nacer; Cabrales, Pedro; Reid, Tony R.; Lee, Min-Jung; Yuno, Akira; Baker, Jonathan; Lee, Sunmin; Trepel, Jane B. 分享 收藏
Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation Jaeger, Alex M.; Stopfer, Lauren; Lee, Sunmin; Gaglia, Giorgio; Sandel, Demi; Santagata, Sandro; Lin, Nancy U.; Trepel, Jane B.; White, Forest; Jacks, Tyler; Lindquist, Susan; Whitesell, Luke 分享 收藏
Metabolic reprogramming associated with aggressiveness occurs in the G-CIMP-high molecular subtypes of IDH1mut lower grade gliomas Ruiz-Rodado, Victor; Malta, Tathiane M.; Seki, Tomohiro; Lita, Adrian; Dowdy, Tyrone; Celiku, Orieta; Cavazos-Saldana, Alejandra; Li, Aiguo; Liu, Yang; Han, Sue; Zhang, Wei; Song, Hua; Davis, Dionne; Lee, Sunmin; Trepel, Jane B.; Sabedot, Thais S.; Munasinghe, Jeeva; Yang, Chunzhang; Herold-Mende, Christel; Gilbert, Mark R.; Cherukuri, Murali Krishna; Noushmehr, Houtan; Larion, Mioara 分享 收藏
RNA Sequencing of the NCI-60: Integration into CellMiner and CellMiner CDB Reinhold, William C.; Varma, Sudhir; Sunshine, Margot; Elloumi, Fathi; Ofori-Atta, Kwabena; Lee, Sunmin; Trebel, Jane B.; Meltzer, Paul S.; Doroshow, James H.; Pommier, Yves 分享 收藏
Induction of Thioredoxin-Interacting Protein by a Histone Deacetylase Inhibitor, Entinostat, Is Associated with DNA Damage and Apoptosis in Esophageal Adenocarcinoma Feingold, Paul L.; Surman, Deborah R.; Brown, Kate; Xu, Yuan; McDuffie, Lucas A.; Shukla, Vivek; Reardon, Emily S.; Crooks, Daniel R.; Trepel, Jane B.; Lee, Sunmin; Lee, Min-Jung; Gao, Shaojian; Xi, Sichuan; McLoughlin, Kaitlin C.; Diggs, Laurence P.; Beer, David G.; Nancarrow, Derek J.; Neckers, Leonard M.; Davis, Jeremy L.; Hoang, Chuong D.; Hernandez, Jonathan M.; Schrump, David S.; Ripley, R. Taylor 分享 收藏
Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer Moses, Michael A.; Kim, Yeong Sang; Rivera-Marquez, Genesis M.; Oshima, Nobu; Watson, Matthew J.; Beebe, Kristin E.; Wells, Catherine; Lee, Sunmin; Zuehlke, Abbey D.; Shao, Hao; Bingman, William E., III; Kumar, Vineet; Malhotra, Sanjay V.; Weigel, Nancy L.; Gestwicki, Jason E.; Trepel, Jane B.; Neckers, Leonard M. 分享 收藏
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation Tigue, Megan L.; Kijima, Toshiki; Prince, Thomas L.; Yim, Kendrick H.; Schwartz, Harvey; Beebe, Kristin; Lee, Sunmin; Budzynski, Marek A.; Williams, Heinric; Trepel, Jane B.; Sistonen, Lea; Calderwood, Stuart; Neckers, Len 分享 收藏
HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation Kijima, Toshiki; Prince, Thomas L.; Tigue, Megan L.; Yim, Kendrick H.; Schwartz, Harvey; Beebe, Kristin; Lee, Sunmin; Budzynski, Marek A.; Williams, Heinric; Trepel, Jane B.; Sistonen, Lea; Calderwood, Stuart; Neckers, Len 分享 收藏
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Targeting the HSP40/HSP70 chaperone axis as a novel strategy to treat castration-resistant prostate cancer Moses, Michael A.; Kim, Yeong Sang; Rivera-Marquez, Genesis; Watson, Matthew J.; Lee, Sunmin; Kravats, Andrea; Wickner, Sue; Gestwicki, Jason; Trepel, Jane; Neckers, Len 分享 收藏
An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans Zuehlke, Abbey D.; Reidy, Michael; Lin, Coney; LaPointe, Paul; Alsomairy, Sarah; Lee, D. Joshua; Rivera-Marquez, Genesis M.; Beebe, Kristin; Prince, Thomas; Lee, Sunmin; Trepel, Jane B.; Xu, Wanping; Johnson, Jill; Masison, Daniel; Neckers, Len 分享 收藏
1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment Ferroni, Claudia; Pepe, Antonella; Kim, Yeong Sang; Lee, Sunmin; Guerrini, Andrea; Parenti, Marco Daniele; Tesei, Anna; Zamagni, Alice; Cortesi, Michela; Zaffaroni, Nadia; De Cesare, Michelandrea; Beretta, Giovanni Luca; Trepel, Jane B.; Malhotra, Sanjay V.; Varchi, Greta 分享 收藏
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