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R

Ruth Riisnaes

The Institute of Cancer Research
H指数:41
被引数:9,977

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荣誉奖项

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Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer

阐明靶向MCL1的分子分层单药及联合治疗策略，以治疗致命性前列腺癌

Nature Communications
IF15.7
2025-10-080
OAAI
Juan M. Jiménez-Vacas; Daniel Westaby; Ines Figueiredo; Alexis De Haven Brandon; Ana Padilha; Wei Yuan; George Seed; Denisa Bogdan; Bora Gurel; Claudia Bertan; Susana Miranda; Maryou Lambros; Antonio J. Montero-Hidalgo; Ilsa Coleman; Ivan Pak Lok Yu; Lorenzo Buroni; Wanting Zeng; Antje J. Neeb; Jon Welti; Jan Rekowski; Roberta Paravati; Florian Gabel; Nicole Pandell; Ana Ferreira; Mateus Crespo; Ruth Riisnaes; Souvik Das; Joe Taylor; Nick Waldron; Emily Hobern; Melanie Valenti; Jian Ning; Ilona Bernett; Kate Liodaki; Thomas Persse; Patricia Galipeau; Scott Wilkinson; Shana Y. Trostel; Fatima Karzai; Cindy H. Chau; Erica L. Beatson; Xiaohu Zhang; Carleen Klumpp-Thomas; Andreas Varkaris; Raul M. Luque; Amanda Swain; Florence Raynaud; Nathan A. Lack; Craig J. Thomas; Gavin Ha; William D. Figg; Marco Bezzi; Adam G. Sowalsky; Peter S. Nelson; Suzanne Carreira; Steven P. Balk; Johann S. de Bono; Adam Sharp
PERSEUS1: An Open-label, Investigator-initiated, Single arm, Phase 2 Trial Testing the Efficacy of Pembrolizumab in Patients with Metastatic Castration-resistant Prostate Cancer with Mismatch Repair Deficiency and Other Immune-sensitive Molecular Subtypes

PERSEUS1：一项开放标签、研究者发起的、单臂、II期临床试验，旨在评估帕博利珠单抗在错配修复缺陷型及其他免疫敏感分子亚型的转移性去势抵抗性前列腺癌患者中的疗效。

European Urology Oncology
IF9.3
2025-06-010
OAAI
Pasquale Rescigno; Maria Dolores Fenor de la Maza; Holly Tovey; Guillermo Villacampa; Fay Cafferty; Stephanie Burnett; Morgaine Stiles; Bora Gurel; Nina Tunariu; Suzanne Carreira; Ines Figueiredo; Nick Beije; Penny Flohr; Emma Hall; Alice Hill; Muneeb Mahmud; Carla Perna; Ajit Sarvadikar; Adam Sharp; Katarzyna Abramovich; Caterina Aversa; Claudia Bertran; Diletta Bianchini; Juliet Carmichael; Khobe Chandran; Mateus Crespo; Emily Cross; Andra Curcean; Ana Ferreira; Rafael Grochot; Christina Guo; Lucy Hamilton; Lesley Harden; Joanne Hunt; Ossian Longoria; Lorena Martos; Susana Miranda; Ruth Riisnaes; Sheena Vadgama; Daniel Westaby; Julie Wilkinson; Christina Yap; Johann S. de Bono
BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-09-170
OAAI
Westaby, Daniel; Jimenez-Vaca, Juan M.; Figueiredo, Ines; Rekowski, Jan; Pettinger, Claire; Gurel, Bora; Lundberg, Arian; Bogdan, Denisa; Buroni, Lorenzo; Neeb, Antje; Padilha, Ana; Taylor, Joe; Zeng, Wanting; Das, Souvik; Hobern, Emily; Riisnaes, Ruth; Crespo, Mateus; Miranda, Susana; Ferreira, Ana; Hanratty, Brian P.; Rodrigues, Daniel Nava; Bertan, Claudia; Seed, George; Maza, Maria de Los Dolores Fenor de La; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Chandran, Khobe; Stavridi, Anastasia; Varkaris, Andreas; Stylianou, Nataly; Hollier, Brett G.; Tunariu, Nina; Balk, Steven P.; Carreira, Suzanne; Yuan, Wei; Nelson, Peter S.; Corey, Eva; Haffner, Michael; de Bono, Johann; Sharp, Adam
RNASEH2B loss and PARP inhibition in advanced prostate cancer
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-06-040
OAAI
Carmichael, Juliet; Figueiredo, Ines; Gurel, Bora; Beije, Nick; Yuan, Wei; Rekowski, Jan; Seed, George; Carreira, Suzanne; Bertan, Claudia; de La Maza, Maria de Los Dolores Fenor; Chandran, Khobe; Neeb, Antje; Welti, Jon; Gallagher, Lewis; Bogdan, Denisa; Crespo, Mateus; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Lu, Jinqiu; Shen, Michael M.; Hall, Emma; Porta, Nuria; Westaby, Daniel; Guo, Christina; Grochot, Rafael; Lord, Christopher J.; Mateo, Joaquin; Sharp, Adam; de Bono, Johann
Thio-2 Inhibits Key Signaling Pathways Required for the Development and Progression of Castration-resistant Prostate Cancer
MOLECULAR CANCER THERAPEUTICS
IF5.5
2024-02-272
OAAI
Neeb, Antje; Figueiredo, Ines; Bogdan, Denisa; Cato, Laura; Stober, Jutta; Jimenez-Vacas, Juan M.; Gourain, Victor; Lee, Irene I.; Seeger, Rebecca; Muhle-Goll, Claudia; Gurel, Bora; Welti, Jonathan; Nava Rodrigues, Daniel; Rekowski, Jan; Qiu, Xintao; Jiang, Yija; Di Micco, Patrizio; Mateos, Borja; Bielskute, Stase; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Buroni, Lorenzo; Ning, Jian; Carreira, Suzanne; Braese, Stefan; Jung, Nicole; Graessle, Simone; Swain, Amanda; Salvatella, Xavier; Plymate, Stephen R.; Al-Lazikani, Bissan; Long, Henry W.; Yuan, Wei; Brown, Myles; Cato, Andrew C. B.; de Bono, Johann S.; Sharp, Adam
Development and Validation of a New BAG-1L-Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer

一种新的BAG-1L-Specific抗体的开发和验证，以量化晚期前列腺癌中的BAG-1L蛋白表达

LABORATORY INVESTIGATION
IF4.2
2023-11-011
OAAI
Neeb, Antje; Figueiredo, Ines; Gurel, Bora; Rodrigues, Daniel Nava; Rekowski, Jan; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Crespo, Mateus; Westaby, Daniel; de La Maza, Maria de Los Dolores Fenor; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Tunariu, Nina; Cato, Andrew C. B.; Plymate, Stephen R.; de Bono, Johann S.; Sharp, Adam
Olaparib and Ceralasertib (AZD6738) in Patients with Triple-Negative Advanced Breast Cancer: Results from Cohort E of the plasmaMATCH Trial (CRUK/15/010)
CLINICAL CANCER RESEARCH
IF10.2
2023-09-294
OAAI
Ring, Alistair; Kilburn, Lucy S.; Pearson, Alex; Moretti, Laura; Afshari-Mehr, Angelica; Wardley, Andrew M.; Gurel, Bora; Macpherson, Iain R.; Riisnaes, Ruth; Baird, Richard D.; Martin, Sue; Roylance, Rebecca; Johnson, Hannah; Ferreira, Ana; Winter, Matthew C.; Dunne, Kathryn; Copson, Ellen; Hickish, Tamas; Burcombe, Russell; Randle, Kat; Serra, Violeta; Llop-Guevara, Alba; Bliss, Judith M.; Turner, Nicolas C.
BCL2 expression is enriched in AR-independent advanced prostate cancer
CANCER RESEARCH
IF16.6
2023-06-021
PRE
Westaby, Daniel; Jimenez-Vacas, Juan M.; Figueiredo, Ines; Pettinger, Claire; Gurel, Bora; Bogdan, Denisa; Rekowski, Jan; Buroni, Lorenzo; Neeb, Antje; Riisnaes, Ruth; Crespo, Mateus; Miranda, Susana; Ferreira, Ana; Rodrigues, Daniel Nava; Seed, George; Bertan, Claudia; de la Maza, Maria de los Dolores Fenor; Guo, Christina; Carmichael, Juliet; Grochot, Rafael; Chandran, Khobe; Varkaris, Andreas; Balk, Steven P.; Yuan, Wei; Carreira, Suzanne; Nelson, Peter S.; Haffner, Michael; Corey, Eva; de Bono, Johann; Sharp, Adam
B7-H3 as a Therapeutic Target in Advanced Prostate Cancer (vol 83, pg 224, 2023)

B7-H3作为晚期前列腺癌的治疗靶点 (第83卷，224页，2023页)

EUROPEAN UROLOGY
IF25.2
2023-06-011
OA
Guo, Christina; Figueiredo, Ines; Gurel, Bora; Neeb, Antje; Seed, George; Crespo, Mateus; Carreira, Suzanne; Rekowski, Jan; Buroni, Lorenzo; Welti, Jon; Bogdan, Denisa; Gallagher, Lewis; Sharp, Adam; de la Maza, Maria D. Fenor; Rescigno, Pasquale; Westaby, Daniel; Chandran, Khobe; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Cali, Bianca; Alimanti, Andrea; Bressan, Silvia; Nguyen, Alana H. T.; Shen, Michael M.; Hawley, Jessica E.; Obradovic, Aleksandar; Drake, Charles G.; Bertan, Claudia; Baker, Chloe; Tunariu, Nina; Yuan, Wei; de Bono, Johann S.
Preliminary evidence of antitumor activity of Ipatasertib (Ipat) and Atezolizumab (A) in glioblastoma (GBM) patients (pts) with PTEN loss in the Phase 1 Ice-CAP trial (NCT03673787)
CANCER RESEARCH
IF16.6
2023-04-142
PRE
Tiu, Crescens; Yau, Wing Hing; Welsh, Liam C.; Jones, Timothy L.; Zachariou, Anna; Prout, Toby; Parmar, Mona; Turner, Alison J.; Daly, Robert W.; Yap, Christina; Crespo, Mateus; Gurel, Bora; Riisnaes, Ruth M.; DeCordova, Shaun A.; Swales, Karen E.; Banerji, Udai; Minchom, Anna R.; Sharp, Adam; de Bono, Johann S.; Lopez, Juanita S.
Immune Biomarkers in Metastatic Castration-resistant Prostate Cancer

转移性去势抵抗性前列腺癌的免疫标志物

EUROPEAN UROLOGY ONCOLOGY
IF9.3
2022-12-0114
PRE
de la Maza, Maria Dolores Fenor; Chandran, Khobe; Rekowski, Jan; Shui, Irene M.; Gurel, Bora; Cross, Emily; Carreira, Suzanne; Yuan, Wei; Westaby, Daniel; Miranda, Susana; Ferreira, Ana; Seed, George; Crespo, Mateus; Figueiredo, Ines; Bertan, Claudia; Gil, Veronica; Riisnaes, Ruth; Sharp, Adam; Rodrigues, Daniel Nava; Rescigno, Pasquale; Tunariu, Nina; Liu, Xiao Qiao; Cristescu, Razvan; Schloss, Charles; Yap, Christina; Bono, Johann S. de
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance
CANCER RESEARCH
IF16.6
2022-10-237
OAAI
Llorca-Cardenosa, Marta J.; Aronson, Lauren I.; Krastev, Dragomir B.; Nieminuszczy, Jadwiga; Alexander, John; Song, Feifei; Dylewska, Malgorzata; Broderick, Ronan; Brough, Rachel; Zimmermann, Astrid; Zenke, Frank T.; Gurel, Bora; Riisnaes, Ruth; Ferreira, Ana; Roumeliotis, Theodoros; Choudhary, Jyoti; Pettitt, Stephen J.; de Bono, Johann; Cervantes, Andres; Haider, Syed; Niedzwiedz, Wojciech; Lord, Christopher J.; Chong, Irene Y.
A Phase I Trial of CT900, a Novel a-Folate Receptor- Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer

新型 α-叶酸受体介导的胸苷酸合成酶抑制剂CT900在具有高级别浆液性卵巢癌患者扩展队列的实体瘤患者中的I期试验

CLINICAL CANCER RESEARCH
IF10.2
2022-08-194
OAAI
Banerjee, Susana; Michalarea, Vasiliki; Ang, Joo Ern; Garces, Alvaro Ingles; Biondo, Andrea; Funingana, Ionut-Gabriel; Little, Martin; Ruddle, Ruth; Raynaud, Florence; Riisnaes, Ruth; Gurel, Bora; Chua, Sue; Tunariu, Nina; Porter, Joanna C.; Prout, Toby; Parmar, Mona; Zachariou, Anna; Turner, Alison; Jenkins, Ben; McIntosh, Stuart; Ainscow, Ed; Minchom, Anna; Lopez, Juanita; de Bono, Johann; Jones, Robert; Hall, Emma; Cook, Natalie; Basu, Bristi; Banerji, Udai
Phase 1, dose-escalation study of guadecitabine (SGI-110) in combination with pembrolizumab in patients with solid tumors

guadecitabine (SGI-110) 联合pembrolizumab治疗实体瘤患者的1期剂量递增研究

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-06-1826
OAAI
Papadatos-Pastos, Dionysis; Yuan, Wei; Pal, Abhijit; Crespo, Mateus; Ferreira, Ana; Gurel, Bora; Prout, Toby; Ameratunga, Malaka; Chenard-Poirier, Maxime; Curcean, Andra; Bertan, Claudia; Baker, Chloe; Miranda, Susana; Masrour, Nahal; Chen, Wentin; Pereira, Rita; Figueiredo, Ines; Morilla, Ricardo; Jenkins, Ben; Zachariou, Anna; Riisnaes, Ruth; Parmar, Mona; Turner, Alison; Carreira, Suzanne; Yap, Christina; Brown, Robert; Tunariu, Nina; Banerji, Udai; Lopez, Juanita; de Bono, Johann; Minchom, Anna
Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial

Toparp-b试验中与PARP抑制剂在前列腺癌中获益相关的生物标志物

CANCER DISCOVERY
IF33.3
2021-05-2799
OAAI
Carreira, Suzanne; Porta, Nuria; Arce-Gallego, Sara; Seed, George; Llop-Guevara, Alba; Bianchini, Diletta; Rescigno, Pasquale; Paschalis, Alec; Bertan, Claudia; Baker, Chloe; Goodall, Jane; Miranda, Susana; Riisnaes, Ruth; Figueiredo, Ines; Ferreira, Ana; Pereira, Rita; Crespo, Mateus; Gurel, Bora; Rodrigues, Daniel Nava; Pettitt, Stephen J.; Yuan, Wei; Serra, Violeta; Rekowski, Jan; Lord, Christopher J.; Hall, Emma; Mateo, Joaquin; de Bono, Johann S.
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer
CANCER RESEARCH
IF16.6
2021-02-1530
OA
Paschalis, Alec; Welti, Jonathan; Neeb, Antje J.; Yuan, Wei; Figueiredo, Ines; Pereira, Rita; Ferreira, Ana; Riisnaes, Ruth; Rodrigues, Daniel Nava; Jimenez-Vacas, Juan M.; Kim, Soojin; Uo, Takuma; Di Micco, Patrizio; Tumber, Anthony; Islam, Md Saiful; Moesser, Marc A.; Abboud, Martine; Kawamura, Akane; Gurel, Bora; Christova, Rossitza; Gil, Veronica S.; Buroni, Lorenzo; Crespo, Mateus; Miranda, Susana; Lambros, Maryou B.; Carreira, Suzanne; Tunariu, Nina; Alimonti, Andrea; Al-Lazikani, Bissan; Schofield, Christopher J.; Plymate, Stephen R.; Sharp, Adam; de Bono, Johann S.
Advanced Prostate Cancer with ATM Loss: PARP and ATR Inhibitors
EUROPEAN UROLOGY
IF25.2
2021-02-0186
OAAI
Neeb, Antje; Herranz, Nicolas; Arce-Gallego, Sara; Miranda, Susana; Buroni, Lorenzo; Yuan, Wei; Athie, Alejandro; Casals, Teresa; Carmichael, Juliet; Nava Rodrigues, Daniel; Gurel, Bora; Rescigno, Pasquale; Rekowski, Jan; Welti, Jon; Riisnaes, Ruth; Gil, Veronica; Ning, Jian; Wagner, Verena; Casanova-Salas, Irene; Cordoba, Sarai; Castro, Natalia; Fenor de la Maza, Maria Dolores; Seed, George; Chandran, Khobe; Ferreira, Ana; Figueiredo, Ines; Bertan, Claudia; Bianchini, Diletta; Aversa, Caterina; Paschalis, Alec; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cristina; Carles, Joan; Swain, Amanda; Sharp, Adam; Gil, Jesus; Serra, Violeta; Lord, Christopher; Carreira, Suzanne; Mateo, Joaquin; de Bono, Johann S.
Targeting the p300/CBP Axis in Lethal Prostate Cancer

靶向p300/CBP轴在致死性前列腺癌中的作用

CANCER DISCOVERY
IF33.3
2021-01-11152
OA
Welti, Jonathan; Sharp, Adam; Brooks, Nigel; Yuan, Wei; McNair, Christopher; Chand, Saswati N.; Pal, Abhijit; Figueiredo, Ines; Riisnaes, Ruth; Gurel, Bora; Rekowski, Jan; Bogdan, Denisa; West, William; Young, Barbara; Raja, Meera; Prosser, Amy; Lane, Jordan; Thomson, Stuart; Worthington, Jenny; Onions, Stuart; Shannon, Jonathan; Paoletta, Silvia; Brown, Richard; Smyth, Don; Harbottle, Gareth W.; Gil, Veronica S.; Miranda, Susana; Crespo, Mateus; Ferreira, Ana; Pereira, Rita; Tunariu, Nina; Carreira, Suzanne; Neeb, Antje J.; Ning, Jian; Swain, Amanda; Taddei, David; Schiewer, Matthew J.; Knudsen, Karen E.; Pegg, Neil; de Bono, Johann S.

研究方向

暂未获取到该数据
J
Johann S. de Bono
H 指数:160论文数:2,491被引数:13.4万
S
Susana Miranda
H 指数:44论文数:341被引数:1.4万
M
Mateus Crespo
H 指数:41论文数:365被引数:5,764
S
Suzanne Carreira
H 指数:49论文数:437被引数:1.4万
I
Ines Figueiredo
H 指数:39论文数:288被引数:7,871
A
Adam Sharp
H 指数:41论文数:495被引数:6,077
D
Daniel Nava Rodrigues
H 指数:49论文数:314被引数:1.2万
B
Bora Gürel
H 指数:37论文数:417被引数:7,026
W
Wei Yuan
H 指数:58论文数:229被引数:1.2万
N
Nina Tunariu
H 指数:50论文数:440被引数:1.8万