Dominic J. Wells - Publications, H-index & Citations

Dominic J. Wells

Royal Veterinary College

51H指数

285论文数

9.3K被引数

收录论文 71

发表时间

Spatiotemporal analysis of dystrophin expression during muscle repair 肌营养不良蛋白表达在肌肉修复过程中的时空分析

Skeletal Muscle

IF4.4

2025-10-04

OAAI

John C.W. Hildyard; Liberty E. Roskrow; Dominic J. Wells; Richard J. Piercy

Ion channels as biomarkers of altered myogenesis in myofiber precursors of Duchenne muscular dystrophy 离子通道作为杜氏肌营养不良症肌纤维前体中肌发生改变的生物标志物

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

IF4.8

2024-03-22

OAAI

Cerchiara, Alessandro Giovanni; Imbrici, Paola; Quarta, Raffaella; Cristiano, Enrica; Boccanegra, Brigida; Caputo, Erika; Wells, Dominic J.; Cappellari, Ornella; De Luca, Annamaria

Longitudinal assessment of skeletal muscle functional mechanics in the DE50-MD dog model of Duchenne muscular dystrophy Duchenne型肌营养不良DE50-MD犬模型中骨骼肌功能力学的纵向评估

DISEASE MODELS & MECHANISMS

IF3.3

2023-12-20

OAAI

Riddell, Dominique O.; Hildyard, John C. W.; Harron, Rachel C. M.; Taylor-Brown, Frances; Kornegay, Joe N.; Wells, Dominic J.; Piercy, Richard J.

Serum inflammatory cytokines as disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy Duchenne肌营养不良DE50-MD犬模型中血清炎性细胞因子作为疾病生物标志物

DISEASE MODELS & MECHANISMS

IF3.3

2022-12-09

OAAI

Riddell, Dominique O.; Hildyard, John C. W.; Harron, Rachel C. M.; Hornby, Natasha L.; Wells, Dominic J.; Piercy, Richard J.

Validation of DE50-MD dogs as a model for the brain phenotype of Duchenne muscular dystrophy 验证DE50-MD犬作为杜氏肌营养不良症的大脑表型模型

DISEASE MODELS & MECHANISMS

IF3.3

2022-03-03

OAAI

Crawford, Abbe H.; Hildyard, John C. W.; Rushing, Sophie A. M.; Wells, Dominic J.; Diez-Leon, Maria; Piercy, Richard J.

Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy

JOURNAL OF NEUROMUSCULAR DISEASES

IF3.4

2021-09-14

OAAI

Verhaart, Ingrid E. C.; Cappellari, Ornella; Tanganyika-de Winter, Christa L.; Plomp, Jaap J.; Nnorom, Sofia; Wells, Kim E.; Hildyard, John C. W.; Bull, David; Aartsma-Rus, Annemieke; Wells, Dominic J.

Author's Response to: Rebuttal to: Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy, Verhaart et al. 2020

JOURNAL OF NEUROMUSCULAR DISEASES

IF3.4

2021-09-14

OAAI

Aartsma-Rus, Annemieke; Verhaart, Ingrid; Wells, Dominic

Improving translatability of preclinical studies for neuromuscular disorders: lessons from the TREAT-NMD Advisory Committee for Therapeutics (TACT)

DISEASE MODELS & MECHANISMS

IF3.3

2020-02-07

OAAI

Willmann, Raffaella; Lee, Joanne; Turner, Cathy; Nagaraju, Kanneboyina; Aartsma-Rus, Annemieke; Wells, Dominic J.; Wagner, Kathryn R.; Csimma, Cristina; Straub, Volker; Grounds, Miranda D.; De Luca, Annamaria

A decade of optimizing drug development for rare neuromuscular disorders through TACT

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2019-11-19

OAAI

Wagner, Kathryn R.; De Luca, Annamaria; Caizergues, Didier; Dowling, James; Goemans, Nathalie; Gordish-Dressman, Heather; Grounds, Miranda D.; Kelly, Michael; Mayhew, Anna; McNally, Elizabeth M.; Zoetis, Tracey; Lee, Joanne; Turner, Cathy; Wells, Dominic J.; Csimma, Cristina; Straub, Volker

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment Cmah-肌营养不良蛋白缺陷型mdx小鼠表现出加速的心脏表型，在肽-PMO外显子跳跃处理后得到改善

HUMAN MOLECULAR GENETICS

IF3.2

2018-10-02

OAAI

Betts, Corinne A.; McClorey, Graham; Healicon, Richard; Hammond, Suzan M.; Manzano, Raquel; Muses, Sofia; Ball, Vicky; Godfrey, Caroline; Merritt, Thomas M.; van Westering, Tirsa; O'Donovan, Liz; Wells, Kim E.; Gait, Michael J.; Wells, Dominic J.; Tyler, Damian; Wood, Matthew J.

Tracking progress: an update on animal models for Duchenne muscular dystrophy 跟踪进展: 杜氏肌营养不良动物模型的更新

DISEASE MODELS & MECHANISMS

IF3.3

2018-06-13

OAAI

Wells, Dominic J.

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

CELL REPORTS

IF6.9

2018-04-01

234

OAAI

Maffioletti, Sara Martina; Sarcar, Shilpita; Henderson, Alexander B. H.; Mannhardt, Ingra; Pinton, Luca; Moyle, Louise Anne; Steele-Stallard, Heather; Cappellari, Ornella; Wells, Kim E.; Ferrari, Giulia; Mitchell, Jamie S.; Tyzack, Giulia E.; Kotiadis, Vassilios N.; Khedr, Moustafa; Ragazzi, Martina; Wang, Weixin; Duchen, Michael R.; Patani, Rickie; Zammit, Peter S.; Wells, Dominic J.; Eschenhagen, Thomas; Tedesco, Francesco Saverio

Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS)

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2018-02-13

OAAI

Kondori, Nazanin R.; Paul, Praveen; Robbins, Jacqueline P.; Liu, Ke; Hildyard, John C. W.; Wells, Dominic J.; de Belleroche, Jacqueline S.

Systemic MV Gene Therapy Close to Clinical Trials for Several Neuromuscular Diseases

MOLECULAR THERAPY

IF12

2017-04-01

OAAI

Wells, Dominic J.

Olfaction variation in mouse husbandry and its implications for refinement and standardization: UK survey of animal scents

LABORATORY ANIMALS

IF1.3

2016-07-10

OAAI

Lopez-Salesansky, Noelia; Mazlan, Nur H.; Whitfield, Lucy E.; Wells, Dominic J.; Burn, Charlotte C.

Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE

IF9.1

2015-12-29

OAAI

Patel, Mehul S.; Lee, Jen; Baz, Manuel; Wells, Claire E.; Bloch, Susannah; Lewis, Amy; Donaldson, Anna V.; Garfield, Benjamin E.; Hopkinson, Nicholas S.; Natanek, Amanda; Man, William D-C; Wells, Dominic J.; Baker, Emma H.; Polkey, Michael I.; Kemp, Paul R.

Improving translational studies: lessons from rare neuromuscular diseases

DISEASE MODELS & MECHANISMS

IF3.3

2015-10-01

OAAI

Wells, Dominic

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

SCIENTIFIC REPORTS

IF3.9

2015-06-26

OAAI

Betts, Corinne A.; Saleh, Amer F.; Carr, Carolyn A.; Muses, Sofia; Wells, Kim E.; Hammond, Suzan M.; Godfrey, Caroline; McClorey, Graham; Woffindale, Caroline; Clarke, Kieran; Wells, Dominic J.; Gait, Michael J.; Wood, Matthew J. A.

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

HUMAN MOLECULAR GENETICS

IF3.2

2015-05-01

112

OAAI

Godfrey, Caroline; Muses, Sofia; McClorey, Graham; Wells, Kim E.; Coursindel, Thibault; Terry, Rebecca L.; Betts, Corinne; Hammond, Suzan; O'Donovan, Liz; Hildyard, John; El Andaloussi, Samir; Gait, Michael J.; Wood, Matthew J.; Wells, Dominic J.

The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development

ORPHANET JOURNAL OF RARE DISEASES

IF3.5

2015-04-23

OAAI

Heslop, Emma; Csimma, Cristina; Straub, Volker; McCall, John; Nagaraju, Kanneboyina; Wagner, Kathryn R.; Caizergues, Didier; Korinthenberg, Rudolf; Flanigan, Kevin M.; Kaufmann, Petra; McNeil, Elizabeth; Mendell, Jerry; Hesterlee, Sharon; Wells, Dominic J.

研究方向