Caryl E. Sortwell - Publications, H-index & Citations

Caryl E. Sortwell

department of translational neuroscience

40H指数

151论文数

5.4K被引数

收录论文 57

发表时间

Complement dysregulation during the early phases of synucleinopathy α-突触核蛋白病早期阶段的补体失调

Acta Neuropathologica

IF9.3

2026-07-20

OAAI

Hina Khan; Mary Gifford; Arash Kordbacheh; Asher Bury; Spencer Panoushek; Allyson Cole-Strauss; Christopher J. Kemp; Kelvin C. Luk; Kathy Steece-Collier; Nathan C. Kuhn; Nicholas M. Kanaan; Caryl E. Sortwell; Joseph R. Patterson; Matthew J. Benskey

Advancing age and sex modulate antidyskinetic efficacy of striatal CaV1.3 gene therapy in a rat model of Parkinson's disease 在帕金森氏病大鼠模型中，年龄和性别的增加调节纹状体CaV1.3基因治疗的抗运动障碍功效

NEUROBIOLOGY OF AGING

IF3.5

2025-05-01

OAAI

Caulfield, Margaret E.; Vander Werp, Molly J.; Stancati, Jennifer A.; Collier, Timothy J.; Sortwell, Caryl E.; Sandoval, Ivette M.; Kordower, Jeffrey H.; Manfredsson, Fredric P.; Steece-Collier, Kathy

The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions 脑源性神经营养因子rs6265 (Val66Met)多态性对治疗性电刺激促进周围神经再生的影晌：一项关于疗法-基因型相互作用的前瞻性研究

MUSCLE & NERVE

IF3.1

2025-04-21

OAAI

Jordan B. Walters; Maria J. Quezada; Suning He; Ciara S. Haynes; Kathy Steece-Collier; Timothy J. Collier; Caryl E. Sortwell; Colin K. Franz

Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats

NPJ PARKINSONS DISEASE

IF8.2

2024-08-23

OAAI

Mercado, Natosha M.; Szarowicz, Carlye; Stancati, Jennifer A.; Sortwell, Caryl E.; Boezwinkle, Samuel A.; Collier, Timothy J.; Caulfield, Margaret E.; Steece-Collier, Kathy

AAV9-Mediated Intrastriatal Delivery of GNAO1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant MiceS

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2024-08-01

OAAI

Roy, Alex J.; Leipprandt, Jeffrey R.; Patterson, Joseph R.; Stoll, Anna C.; Kemp, Christopher J.; Oula, Zaipo-Tcheisian D.; Mola, Tyler; Batista, Ana R.; Sortwell, Caryl E.; Sena-Esteves, Miguel; Neubig, Richard R.

Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition

JOURNAL OF NEUROINFLAMMATION

IF10.1

2024-04-25

OAAI

Stoll, Anna C.; Kemp, Christopher J.; Patterson, Joseph R.; Kubik, Michael; Kuhn, Nathan; Benskey, Matthew; Duffy, Megan F.; Luk, Kelvin C.; Sortwell, Caryl E.

Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions

NEUROBIOLOGY OF DISEASE

IF5.6

2024-02-01

OAAI

Stoll, Anna C.; Kemp, Christopher J.; Patterson, Joseph R.; Howe, Jacob W.; Steece-Collier, Kathy; Luk, Kelvin C.; Sortwell, Caryl E.; Benskey, Matthew J.

Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils

NPJ PARKINSONS DISEASE

IF8.2

2024-01-03

OAAI

Patterson, Joseph R.; Kochmanski, Joseph; Stoll, Anna C.; Kubik, Michael; Kemp, Christopher J.; Duffy, Megan F.; Thompson, Kajene; Howe, Jacob W.; Cole-Strauss, Allyson; Kuhn, Nathan C.; Miller, Kathryn M.; Nelson, Seth; Onyekpe, Christopher U.; Beck, John S.; Counts, Scott E.; Bernstein, Alison I.; Steece-Collier, Kathy; Luk, Kelvin C.; Sortwell, Caryl E.

Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in a-synuclein pre-formed fibril (PFF)-injected mice

TOXICOLOGICAL SCIENCES

IF4.1

2023-08-22

OAAI

Boyd, Sierra L.; Kuhn, Nathan C.; Patterson, Joseph R.; Stoll, Anna C.; Zimmerman, Sydney A.; Kolanowski, Mason R.; Neubecker, Joseph J.; Luk, Kelvin C.; Ramsson, Eric S.; Sortwell, Caryl E.; Bernstein, Alison, I

Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

NEUROBIOLOGY OF DISEASE

IF5.6

2023-06-01

OAAI

Caulfield, Margaret E.; Vander Werp, Molly J.; Stancati, Jennifer A.; Collier, Timothy J.; Sortwell, Caryl E.; Sandoval, Ivette M.; Manfredsson, Fredric P.; Steece-Collier, Kathy

Leveraging the preformed fibril model to distinguish between alpha-synuclein inclusion- and nigrostriatal degeneration-associated immunogenicity

NEUROBIOLOGY OF DISEASE

IF5.6

2022-09-01

OAAI

Stoll, Anna C.; Sortwell, Caryl E.

BDNF rs6265 Genotype Influences Outcomes of Pharmacotherapy and Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease

NEUROMODULATION

IF3.5

2022-08-01

OAAI

Sortwell, Caryl E.; Hacker, Mallory L.; Fischer, David Luke; Konrad, Peter E.; Davis, Thomas L.; Neimat, Joseph S.; Wang, Lily; Song, Yanna; Mattingly, Zach R.; Cole-Strauss, Allyson; Lipton, Jack W.; Charles, P. David

Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein

NPJ PARKINSONS DISEASE

IF8.2

2022-05-24

OAAI

Patterson, Joseph R.; Hirst, Warren D.; Howe, Jacob W.; Russell, Christopher P.; Cole-Strauss, Allyson; Kemp, Christopher J.; Duffy, Megan F.; Lamp, Jared; Umstead, Andrew; Kubik, Michael; Stoll, Anna C.; Vega, Irving E.; Steece-Collier, Kathy; Chen, Yi; Campbell, Anne C.; Nezich, Catherine L.; Glajch, Kelly E.; Sortwell, Caryl E.

Dopaminergic Positron Emission Tomography Imaging in the Alpha-Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease

MOVEMENT DISORDERS

IF7.6

2022-05-07

OAAI

Sossi, Vesna; Patterson, Joseph R.; McCormick, Siobhan; Kemp, Christopher J.; Miller, Kathryn M.; Stoll, Anna C.; Kuhn, Nathan; Kubik, Michael; Kochmanski, Joseph; Luk, Kelvin C.; Sortwell, Caryl E.

Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory

TRANSLATIONAL PSYCHIATRY

IF6.2

2022-03-07

OAAI

Jaehne, Emily J.; Kent, Jessica N.; Antolasic, Emily J.; Wright, Bradley J.; Spiers, Jereme G.; Creutzberg, Kerstin C.; De Rosa, Federico; Riva, Marco A.; Sortwell, Caryl E.; Collier, Timothy J.; van den Buuse, Maarten

Preformed fibrils generated from mouse alpha-synuclein produce more inclusion pathology in rats than fibrils generated from rat alpha-synuclein

PARKINSONISM & RELATED DISORDERS

IF3.4

2021-08-01

OAAI

Howe, Jacob W.; Sortwell, Caryl E.; Duffy, Megan F.; Kemp, Christopher J.; Russell, Christopher P.; Kubik, Michael; Patel, Pooja; Luk, Kelvin C.; El-Agnaf, Omar M. A.; Patterson, Joseph R.

Synucleinopathy-associated pathogenesis in Parkinson's disease and the potential for brain-derived neurotrophic factor

NPJ PARKINSONS DISEASE

IF8.2

2021-04-12

OAAI

Miller, Kathryn M.; Mercado, Natosha M.; Sortwell, Caryl E.

α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease Α-突触核蛋白反义寡核苷酸作为帕金森病的疾病缓解疗法

JCI INSIGHT

IF6.1

2021-03-08

OAAI

Cole, Tracy A.; Zhao, Hien; Collier, Timothy J.; Sandoval, Ivette; Sortwell, Caryl E.; Steece-Collier, Kathy; Daley, Brian F.; Booms, Alix; Lipton, Jack; Welch, Mackenzie; Berman, Melissa; Jandreski, Luke; Graham, Danielle; Weihofen, Andreas; Celano, Stephanie; Schulz, Emily; Cole-Strauss, Allyson; Luna, Esteban; Quach, Duc; Mohan, Apoorva; Bennett, C. Frank; Swayze, Eric E.; Kordasiewicz, Holly B.; Luk, Kelvin C.; Paumier, Katrina L.

Next-Generation Diamond Electrodes for Neurochemical Sensing: Challenges and Opportunities 用于神经化学传感的下一代金刚石电极: 挑战与机遇

MICROMACHINES

IF3

2021-01-26

OAAI

Purcell, Erin K.; Becker, Michael F.; Guo, Yue; Hara, Seth A.; Ludwig, Kip A.; McKinney, Collin J.; Monroe, Elizabeth M.; Rechenberg, Robert; Rusinek, Cory A.; Saxena, Akash; Siegenthaler, James R.; Sortwell, Caryl E.; Thompson, Cort H.; Trevathan, James K.; Witt, Suzanne; Li, Wen

The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats

NEUROBIOLOGY OF DISEASE

IF5.6

2021-01-01

OAAI

Mercado, Natosha M.; Stancati, Jennifer A.; Sortwell, Caryl E.; Mueller, Rebecca L.; Boezwinkle, Samuel A.; Duffy, Megan F.; Fischer, D. Luke; Sandoval, Ivette M.; Manfredsson, Fredric P.; Collier, Timothy J.; Steece-Collier, Kathy

研究方向