Christine Orengo - Publications, H-index & Citations

Christine Orengo

Institute of Structural and Molecular Biology

37H指数

161论文数

1.1W被引数

收录论文 33

发表时间

TEDLH: domain HMMs for sensitive detection of remote homologues TEDLH：用于远程同源体敏感检测的域隐马尔可夫模型

Bioinformatics

IF5.4

2026-07-03

OAAI

Claudia Alvarez-Carreño; Anton S Petrov; Vaishali P Waman; Ian Sillitoe; Christine Orengo; null

Invisible Infrastructure at Risk: Funding Crises Threaten Global Bioscience Research 隐形基础设施面临风险：资金危机威胁全球生物科学研究

Genetics

IF5.1

2026-01-01

PREAI

Valerie Wood; Elspeth A. Bruford; Steven J Marygold; Valerie B. O’Donnell; Katja Röper; Jamie A Davies; Christine Orengo; Paul Nurse; Neil Hall

Leveraging protein language models and a scoring function for indel characterization and transfer learning 利用蛋白质语言模型和评分函数进行插入/缺失表征和迁移学习

Patterns

IF7.4

2025-11-26

OAAI

Oriol Gracia Carmona; Vilde Leipart; Gro V. Amdam; Christine Orengo; Franca Fraternali

AlphaFold Protein Structure Database 2025: a redesigned interface and updated structural coverage AlphaFold蛋白质结构数据库2025：重新设计的界面和更新的结构覆盖范围

NUCLEIC ACIDS RESEARCH

IF13.1

2025-11-01

PREAI

Bertoni, Damian; Tsenkov, Maxim; Magana, Paulyna; Nair, Sreenath; Pidruchna, Ivanna; Querino Lima Afonso, Marcelo; Midlik, Adam; Paramval, Urmila; Lawal, Dare; Tanweer, Ahsan; Last, Meera; Patel, Risha; Laydon, Agata; Lasecki, Dariusz; Dietrich, Nick; Tomlinson, Hamish; ZIDek, Augustin; Green, Tim; Kovalevskiy, Oleg; Lau, Andy; Kandathil, Shaun; Bordin, Nicola; Sillitoe, Ian; Mirdita, Milot; Jones, David; Orengo, Christine; Steinegger, Martin; Fleming, Jennifer R.; Velankar, Sameer

Assessing structure-function impacts on Vitellogenin by leveraging allelic variant found in honey bee subspecies Apis mellifera mellifera 通过利用蜜蜂亚种Apis mellifera mellifera中发现的等位基因变异，评估结构-功能对卵黄原蛋白的影响。

iScience

IF4.1

2025-07-29

OAAI

Vilde Leipart; Oriol Gracia Carmona; Christine Orengo; Franca Fraternali; Gro V. Amdam

GOBeacon: An ensemble model for protein function prediction enhanced by contrastive learning GOBeacon: 一种通过对比学习增强的蛋白质功能预测集成模型

Protein Science

IF5.2

2025-06-22

OAAI

Weining Lin; David Miller; Zhonghui Gu; Christine Orengo

CATH v4.4: major expansion of CATH by experimental and predicted structural data CATH v4.4: 通过实验和预测的结构数据对CATH进行重大扩展

NUCLEIC ACIDS RESEARCH

IF13.1

2024-11-20

OAAI

Waman, Vaishali P.; Bordin, Nicola; Lau, Andy; Kandathil, Shaun; Wells, Jude; Miller, David; Velankar, Sameer; Jones, David T.; Sillitoe, Ian; Orengo, Christine

Enhancing missense variant pathogenicity prediction with protein language models using VariPred

SCIENTIFIC REPORTS

IF3.9

2024-04-07

OAAI

Lin, Weining; Wells, Jude; Wang, Zeyuan; Orengo, Christine; Martin, Andrew C. R.

Broad functional profiling of fission yeast proteins using phenomics and machine learning 使用表型组学和机器学习对裂变酵母蛋白进行广泛的功能分析

ELIFE

IF0

2023-10-03

OAAI

Rodriguez-Lopez, Maria; Bordin, Nicola; Lees, Jon; Scholes, Harry; Hassan, Shaimaa; Saintain, Quentin; Kamrad, Stephan; Orengo, Christine; Baehler, Juerg

The opportunities and challenges posed by the new generation of deep learning-based protein structure predictors 基于深度学习的新一代蛋白质结构预测器的机遇与挑战

CURRENT OPINION IN STRUCTURAL BIOLOGY

IF7

2023-04-01

OAAI

Varadi, Mihaly; Bordin, Nicola; Orengo, Christine; Velankar, Sameer

Novel machine learning approaches revolutionize protein knowledge 新的机器学习方法彻底改变了蛋白质知识

TRENDS IN BIOCHEMICAL SCIENCES

IF11

2023-04-01

OAAI

Bordin, Nicola; Dallago, Christian; Heinzinger, Michael; Kim, Stephanie; Littmann, Maria; Rauer, Clemens; Steinegger, Martin; Rost, Burkhard; Orengo, Christine

AlphaFold2 reveals commonalities and novelties in protein structure space for 21 model organisms AlphaFold2揭示了21种模型生物在蛋白质结构空间中的共性和新颖性

COMMUNICATIONS BIOLOGY

IF5.1

2023-02-08

OAAI

Bordin, Nicola; Sillitoe, Ian; Nallapareddy, Vamsi; Rauer, Clemens; Lam, Su Datt; Waman, Vaishali P.; Sen, Neeladri; Heinzinger, Michael; Littmann, Maria; Kim, Stephanie; Velankar, Sameer; Steinegger, Martin; Rost, Burkhard; Orengo, Christine

3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources 3d信标: 通过蛋白质结构数据资源的联合网络减少蛋白质序列和结构之间的差距

GIGASCIENCE

IF3.9

2022-11-30

OAAI

Varadi, Mihaly; Nair, Sreenath; Sillitoe, Ian; Tauriello, Gerardo; Anyango, Stephen; Bienert, Stefan; Borges, Clemente; Deshpande, Mandar; Green, Tim; Hassabis, Demis; Hatos, Andras; Hegedus, Tamas; Hekkelman, Maarten L.; Joosten, Robbie; Jumper, John; Laydon, Agata; Molodenskiy, Dmitry; Piovesan, Damiano; Salladini, Edoardo; Salzberg, Steven L.; Sommer, Markus J.; Steinegger, Martin; Suhajda, Erzsebet; Svergun, Dmitri; Tenorio-Ku, Luiggi; Tosatto, Silvio; Tunyasuvunakool, Kathryn; Waterhouse, Andrew Mark; Zidek, Augustin; Schwede, Torsten; Orengo, Christine; Velankar, Sameer

InterPro in 2022 InterPro 2022年

NUCLEIC ACIDS RESEARCH

IF13.1

2022-11-09

1.1K

OAAI

Paysan-Lafosse, Typhaine; Blum, Matthias; Chuguransky, Sara; Grego, Tiago; Pinto, Beatriz Lazaro; Salazar, Gustavo A.; Bileschi, Maxwell L.; Bork, Peer; Bridge, Alan; Colwell, Lucy; Gough, Julian; Haft, Daniel H.; Letunic, Ivica; Marchler-Bauer, Aron; Mi, Huaiyu; Natale, Darren A.; Orengo, Christine A.; Pandurangan, Arun P.; Rivoire, Catherine; Sigrist, Christian J. A.; Sillitoe, Ian; Thanki, Narmada; Thomas, Paul D.; Tosatto, Silvio C. E.; Wu, Cathy H.; Bateman, Alex

Contrastive learning on protein embeddings enlightens midnight zone

genomics proteomics bioinformatics

IF2.8

2022-06-11

OAAI

Heinzinger, Michael; Littmann, Maria; Sillitoe, Ian; Bordin, Nicola; Orengo, Christine; Rost, Burkhard

Transmission of SARS-CoV-2 from humans to animals and potential host adaptation

NATURE COMMUNICATIONS

IF15.7

2022-05-27

OAAI

Tan, Cedric C. S.; Lam, Su Datt; Richard, Damien; Owen, Christopher J.; Berchtold, Dorothea; Orengo, Christine; Nair, Meera Surendran; Kuchipudi, Suresh, V; Kapur, Vivek; van Dorp, Lucy; Balloux, Francois

InterPro in 2019: improving coverage, classification and access to protein sequence annotations

NUCLEIC ACIDS RESEARCH

IF13.1

2018-11-06

1.1K

OAAI

Mitchell, Alex L.; Attwood, Teresa K.; Babbitt, Patricia C.; Blum, Matthias; Bork, Peer; Bridge, Alan; Brown, Shoshana D.; Chang, Hsin-Yu; El-Gebali, Sara; Fraser, Matthew I.; Gough, Julian; Haft, David R.; Huang, Hongzhan; Letunic, Ivica; Lopez, Rodrigo; Luciani, Aurelien; Madeira, Fabio; Marchler-Bauer, Aron; Mi, Huaiyu; Natale, Darren A.; Necci, Marco; Nuka, Gift; Orengo, Christine; Pandurangan, Arun P.; Paysan-Lafosse, Typhaine; Pesseat, Sebastien; Potter, Simon C.; Qureshi, Matloob A.; Rawlings, Neil D.; Redaschi, Nicole; Richardson, Lorna J.; Rivoire, Catherine; Salazar, Gustavo A.; Sangrador-Vegas, Amaia; Sigrist, Christian J. A.; Sillitoe, Ian; Sutton, Granger G.; Thanki, Narmada; Thomas, Paul D.; Tosatto, Silvio C. E.; Yong, Siew-Yit; Finn, Robert D.

Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury

PAIN

IF5.5

2018-10-16

OAAI

Baskozos, Georgios; Dawes, John M.; Austin, Jean S.; Antunes-Martins, Ana; McDermott, Lucy; Clark, Alex J.; Trendafilova, Teodora; Lees, Jon G.; McMahon, Stephen B.; Mogil, Jeffrey S.; Orengo, Christine; Bennett, David L.

Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells

BIOCHEMICAL JOURNAL

IF4.3

2018-06-06

OAAI

Tsuchiya, Yugo; Zhyvoloup, Alexander; Bakovic, Jovana; Thomas, Naam; Yu, Bess Yi Kun; Das, Sayoni; Orengo, Christine; Newell, Clare; Ward, John; Saladino, Giorgio; Comitani, Federico; Gervasio, Francesco L.; Malanchuk, Oksana M.; Khoruzhenko, Antonina I.; Filonenko, Valeriy; Peak-Chew, Sew Yeu; Skehel, Mark; Gout, Ivan

The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy

PAIN

IF5.5

2016-05-01

239

OAAI

Themistocleous, Andreas C.; Ramirez, Juan D.; Shillo, Pallai R.; Lees, Jonathan G.; Selvarajah, Dinesh; Orengo, Christine; Tesfaye, Solomon; Rice, Andrew S. C.; Bennett, David L. H.

研究方向