Wenhan Lu - Publications, H-index & Citations

Wenhan Lu

broad institute of mit and harvard

13H指数

37论文数

3.8K被引数

收录论文 10

发表时间

Effect heterogeneity reveals complex pleiotropic effects of rare coding variants 效应异质性揭示了稀有编码变异的复杂多效性效应

American Journal of Human Genetics

IF8.1

2026-09-30

PREAI

Wenhan Lu; Siwei Chen; Chiara Auwerx; Jack Fu; Danielle Posthuma; Benjamin M. Neale; Luke J. O’Connor; Konrad J. Karczewski

Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction 合并症肺部疾病和性状的多性状和多祖先遗传分析可改善遗传发现和多基因风险预测

Nature Genetics

IF29

2026-01-21

PREAI

Yixuan He; Wenhan Lu; Yon Ho Jee; Mu-Yi Shih; Ying Wang; Kristin Tsuo; David C. Qian; James A. Diao; Hailiang Huang; Chirag J. Patel; Jinyoung Byun; Bogdan Pasaniuc; Elizabeth G. Atkinson; Christopher I. Amos; Yen-Chen Anne Feng; Matthew Moll; Michael H. Cho; Alicia R. Martin

Dissecting pleiotropy to gain mechanistic insights into human disease 解析多效性以获得对人类疾病机制的见解

Nature Reviews Genetics

IF52

2025-11-28

PREAI

Yon Ho Jee; Yixuan He; Wenhan Lu; Yue Shi; Daniel Lazarev; Mark J. Daly; Mary Pat Reeve; Alicia R. Martin

Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects 全英生物银行全基因组关联分析增强了祖先富集效应的发现和解析

Nature Genetics

IF0

2025-09-18

PREAI

Konrad J. Karczewski; Rahul Gupta; Masahiro Kanai; Wenhan Lu; Kristin Tsuo; Ying Wang; Raymond K. Walters; Patrick Turley; Shawneequa Callier; Nirav N. Shah; Nikolas Baya; Duncan S. Palmer; Jacqueline I. Goldstein; Gopal Sarma; Matthew Solomonson; Nathan Cheng; Sam Bryant; Claire Churchhouse; Caroline M. Cusick; Timothy Poterba; John Compitello; Daniel King; Wei Zhou; Cotton Seed; Hilary K. Finucane; Mark J. Daly; Benjamin M. Neale; Elizabeth G. Atkinson; Alicia R. Martin

Quasi-Likelihood Estimation in the Fractional Black-Scholes Model 分数Black-Scholes模型中的准似然估计

MATHEMATICS

IF2.2

2025-09-15

OAAI

Lu, Wenhan; Yan, Litan; Xia, Yiang

HOW MUCH DO RARE DE NOVO VARIANTS CONTRIBUTE TO AUTISM?

EUROPEAN NEUROPSYCHOPHARMACOLOGY

IF6.7

2024-10-01

PREAI

Nadig, Ajay; Lu, Wenhan; Fu, Jack; Satterstrom, F. Kyle; Karczewski, Konrad; Talkowski, Michael; Robinson, Elise; O'Connor, Luke

Cimifugin Relieves Histamine-Independent Itch in Atopic Dermatitis via Targeting the CQ Receptor MrgprA3

ACS OMEGA

IF4.3

2024-01-31

OAAI

Zheng, Jie; Gu, Anqi; Kong, Lingxuan; Lu, Wenhan; Xia, Jingsheng; Hu, Huijuan; Hong, Min

CHARR efficiently estimates contamination from DNA sequencing data

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2023-12-01

OAAI

Lu, Wenhan; Gauthier, Laura D.; Poterba, Timothy; Giacopuzzi, Edoardo; Goodrich, Julia K.; Stevens, Christine R.; King, Daniel; Daly, Mark J.; Neale, Benjamin M.; Karczewski, Konrad J.

Mfat-1 ameliorates cachexia after hypoxic-ischemic brain damage in mice by protecting the hypothalamus-pituitary-adrenal axis

LIFE SCIENCES

IF5.1

2023-11-01

PREAI

Zhang, Yumeng; Lu, Wenhan; Li, Xiaoxue; Wang, Yu; Li, Lin; Dai, Yifan; Yang, Haiyuan; Wang, Ying

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes

CELL GENOMICS

IF9

2022-09-01

OAAI

Karczewski, Konrad J.; Solomonson, Matthew; Chao, Katherine R.; Goodrich, Julia K.; Tiao, Grace; Lu, Wenhan; Riley-Gillis, Bridget M.; Tsai, Ellen A.; Kim, Hye In; Zheng, Xiuwen; Rahimov, Fedik; Esmaeeli, Sahar; Grundstad, A. Jason; Reppell, Mark; Waring, Jeff; Jacob, Howard; Sexton, David; Bronson, Paola G.; Chen, Xing; Hu, Xinli; Goldstein, Jacqueline I.; King, Daniel; Vittal, Christopher; Poterba, Timothy; Palmer, Duncan S.; Churchhouse, Claire; Howrigan, Daniel P.; Zhou, Wei; Watts, Nicholas A.; Nguyen, Kevin; Nguyen, Huy; Mason, Cara; Farnham, Christopher; Tolonen, Charlotte; Gauthier, Laura D.; Gupta, Namrata; MacArthur, Daniel G.; Rehm, Heidi L.; Seed, Cotton; Philippakis, Anthony A.; Daly, Mark J.; Davis, J. Wade; Runz, Heiko; Miller, Melissa R.; Neale, Benjamin M.

研究方向