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J

John Spencer

university of sussex
H指数:69
被引数:1.9万
浏览量:0

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A Modular Synthesis of C5-Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

通过分子间Pummerer重排的C5-硫醚基噻唑的模块化合成：一种药物化学中尚未充分开发的骨架

Angewandte Chemie-International Edition
IF16.9
2026-08-170
OAAI
Joe L. Smy; Theo C. Webb; Barnaby W. Greenland; S. Mark Roe; John Spencer; Storm Hassell-Hart
Synthesis of N-Acetyl-D- and -L-Leucine-13C6 Tool Compounds in Neurodegenerative Disease

合成神经退行性疾病中N-乙酰基-D-和-L-亮氨酸-13C6工具化合物

ChemMedChem
IF3.4
2026-05-150
OAAI
Damien Crepin; Andrew McGown; Dawn Shepherd; Rebecca Braine; Manvendra Sharma; Jordan Nafie; João Gabriel Ribeiro; G. Dan Pantoş; Grant Churchill; Frances M. Platt; John Spencer
Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt

使用小分子稳定剂rezatapopt靶向p53癌突变体Y220C、Y220N和Y220S

Cell Death & Disease
IF9.6
2026-02-260
OAAI
Danai Mavridi; Julianne S. Funk; Dimitrios-Ilias Balourdas; Andreas Krämer; Raysa Khan Tareque; Oleg Timofeev; John Spencer; Thorsten Stiewe; Andreas C. Joerger
Removal of Toxic Metabolites—Chelation: Manganese Disorders

毒性代谢物的去除—螯合：锰障碍

Journal of Inherited Metabolic Disease
IF3.8
2025-11-020
OAAI
Hendrik Vogt; George E. Kostakis; Rupert Purchase; John Spencer; Karin Tuschl
A Review on Luminescent Benzoselenadiazole Derivatives: Comparison with Benzothiadiazoles, Properties, Applications, and Trends

《发光苯并硒二唑衍生物综述：与苯并噻二唑的比较、性质、应用及趋势》

CHEMISTRY-AN ASIAN JOURNAL
IF3.3
2025-06-011
OAAI
Neto, Brenno A. D.; Spencer, John; Lapis, Alexandre A. M.
Particle size effects on vapour uptake and release dynamics in metal-organic frameworks
CHEMICAL COMMUNICATIONS
IF4.2
2025-04-010
OA
Nicks, Joshua; Mudure, Cosmin; James, Jordan; McDougall, Alexander; Hughes, William O. H.; Spencer, John; Duren, Tina; Burrows, Andrew D.
Single enantiomer propeller-shaped polynuclear complexes as catalysts-proof-of-concept for enantioinduction in a Michael addition reaction

单一对映异构体螺旋桨状多核配合物作为催化剂：Michael加成反应中对映诱导的可行性证明

ROYAL SOCIETY OPEN SCIENCE
IF2.9
2025-03-270
OA
Maddocks, Joe; Mahesh, Mohan; Sampani, Stavroula I.; Dixon, Alexander C.; Nielsen, Christian D. -T.; Kumar, Prashant; Akien, Geoffrey R.; Spencer, John; Abdul-Sada, Alaa; Turner, John F. C.; Spivey, Alan C.; Kostakis, George E.
Novel mitochondrial-targeted alkyl chains act as fungal specific inhibitors of C. neoformans
FRONTIERS IN MICROBIOLOGY
IF4.5
2025-02-040
OAAI
Edrich, Elizabeth S. M.; Young, Luke; Spencer, John; Mcgown, Andrew; Moore, Anthony L.; Gourlay, Campbell W.
Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant Linkers

使用醛-炔-胺偶联产生药物化学相关的连接体

ACS MEDICINAL CHEMISTRY LETTERS
IF4
2025-01-250
OAAI
Mcgown, Andrew; Vetma, Vesna; Crepin, Damien; Lin, Yan; Adcock, Claire; Craigon, Conner; Nafie, Jordan; von Emloh, Daniel; Sutton, Lea; Bailey, Kiera; Edmunds, Lewis; Sharma, Manvendra; Wilden, Jonathan D.; Coles, Simon J.; Tizzard, Graham J.; Farnaby, William; Ciulli, Alessio; Kostakis, George E.; Spencer, John
Synthesis of Core-Functionalised Naphthalenediimides from Naphthalenetetracarboxylic Dianhydride using a Vibratory Ball Mill: Bromination, Imidization and Heck-Type Reactions
CHEMISTRY-A EUROPEAN JOURNAL
IF3.7
2025-01-230
PRE
Dodson, E. M.; Lawson, T. E.; Lai-Morrice, J.; Emerit, H.; Guest, D. P.; Panther, L. A.; Gonzalez-Mendez, R.; Roe, S. M.; Goodall, C. A. I.; Bagley, M. C.; Spencer, J.; Greenland, B. W.
Characterization of the Active Enantiomer and Mapping of the Stereospecific Intermolecular Pattern of a Reference P2X7 Allosteric Antagonist

活性对映异构体的表征及参考P2X7别构拮抗剂立体特异性分子间模式的映射

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE
IF3.7
2025-01-220
PRE
Mcgown, A; Renault, N; Barczyk, A; Nafie, J; Barluzzi, L; Guest, D; Tizzard, GJ; Coles, SJ; Leach, D; von Emloh, D; Sutton, L; Bailey, K; Edmunds, L; Greenland, BW; Millet, R; Spencer, J; Dezitter, X
Controlling the Uptake and Release of Semiochemicals in Channel-Type Metal-Organic Frameworks Through Pore Expansion
CHEMISTRY-A EUROPEAN JOURNAL
IF3.7
2024-05-220
OA
Nicks, Joshua; Shearer, Greig C.; Paul-Taylor, Joseph; Lai-Morrice, James; Dadswell, Chris; Guest, Daniel; Hughes, William O. H.; Spencer, John; Dueren, Tina; Burrows, Andrew D.
Introduction to 'Medicinal Chemistry Small Molecule Probes'
RSC CHEMICAL BIOLOGY
IF3.1
2024-01-010
OAAI
Nixon, Gemma; Rahman, Khondaker Miraz; Spencer, John
Investigating the prevalence of pulmonary hypertension amongst individuals with heart failure: a systematic review and meta-analysis
THORAX
IF7.7
2023-11-060
OA
Khan, M.; Suribhatla, R.; Spencer, J.; Daniel, N.; Kartsonaki, C.
Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites
PHARMACEUTICS
IF5.5
2023-10-103
OAAI
Reyser, Thibaud; Paloque, Lucie; Nguyen, Michel; Augereau, Jean-Michel; Fuchter, Matthew John; Lopez, Marie; Arimondo, Paola B.; Hassell-Hart, Storm; Spencer, John; Di Stefano, Luisa; Benoit-Vical, Francoise
A change of direction through trans-bis-silylation of alkynes
NATURE SYNTHESIS
IF20
2023-06-220
PRE
Spencer, John
Chirality: a key parameter in chemical probes
RSC CHEMICAL BIOLOGY
IF3.1
2023-01-014
OAAI
McGown, Andrew; Nafie, Jordan; Otayfah, Mohammed; Hassell-Hart, Storm; Tizzard, Graham J. J.; Coles, Simon J. J.; Banks, Rebecca; Marsh, Graham P. P.; Maple, Hannah J. J.; Kostakis, George E. E.; Silvestri, Ilaria Proietti; Colbon, Paul; Spencer, John
Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction
ORGANIC LETTERS
IF5
2022-10-2019
OAAI
Hassell-Hart, Storm; Speranzini, Elisa; Srikwanjai, Sirihathai; Hossack, Euan; Roe, S. Mark; Fearon, Daren; Akinbosede, Daniel; Hare, Stephen; Spencer, John
A Convenient, Rapid, Conventional Heating Route to MIDA Boronates
MOLECULES
IF4.6
2022-08-091
OAAI
McGown, Andrew; Edmonds, Anthony K.; Guest, Daniel; Holmes, Verity L.; Dadswell, Chris; Gonzalez-Mendez, Ramon; Goodall, Charles A., I; Bagley, Mark C.; Greenland, Barnaby W.; Spencer, John
Solvent-Free Synthesis of Core-Functionalised Naphthalene Diimides by Using a Vibratory Ball Mill: Suzuki, Sonogashira and Buchwald-Hartwig Reactions
CHEMISTRY-A EUROPEAN JOURNAL
IF3.7
2022-07-135
OAAI
Panther, Lydia A.; Guest, Daniel P.; McGown, Andrew; Emerit, Hugo; Tareque, Raysa Khan; Jose, Arathy; Dadswell, Chris M.; Coles, Simon J.; Tizzard, Graham J.; Gonzalez-Mendez, Ramon; Goodall, Charles A., I; Bagley, Mark C.; Spencer, John; Greenland, Barnaby W.

研究方向

暂未获取到该数据
S
Simon J. Coles
H 指数:61论文数:3,266被引数:2.0万
A
Andrew McGown
H 指数:14论文数:91被引数:1,174
G
Graham J. Tizzard
H 指数:28论文数:406被引数:2,494
G
George E. Κostakis
H 指数:38论文数:502被引数:5,650
S
Storm Hassell‐Hart
H 指数:9论文数:43被引数:342
D
Daniel Guest
H 指数:8论文数:24被引数:241
M
Melvyn B. Ansell
H 指数:8论文数:33被引数:338
O
Oscar Navarro
H 指数:33论文数:150被引数:5,966
B
Barnaby W. Greenland
H 指数:27论文数:101被引数:4,326
A
Andreas C. Joerger
H 指数:41论文数:127被引数:8,228