John Spencer - Publications, H-index & Citations

John Spencer

university of sussex

69H指数

778论文数

2.0W被引数

收录论文 133

发表时间

A Modular Synthesis of C5-Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry 通过分子间Pummerer重排的C5-硫醚基噻唑的模块化合成：一种药物化学中尚未充分开发的骨架

Angewandte Chemie-International Edition

IF16.9

2026-08-17

OAAI

Joe L. Smy; Theo C. Webb; Barnaby W. Greenland; S. Mark Roe; John Spencer; Storm Hassell-Hart

Synthesis of N-Acetyl-D- and -L-Leucine-13C6 Tool Compounds in Neurodegenerative Disease 合成神经退行性疾病中N-乙酰基-D-和-L-亮氨酸-13C6工具化合物

ChemMedChem

IF3.4

2026-05-15

OAAI

Damien Crepin; Andrew McGown; Dawn Shepherd; Rebecca Braine; Manvendra Sharma; Jordan Nafie; João Gabriel Ribeiro; G. Dan Pantoş; Grant Churchill; Frances M. Platt; John Spencer

Targeting the p53 cancer mutants Y220C, Y220N, and Y220S with the small-molecule stabilizer rezatapopt 使用小分子稳定剂rezatapopt靶向p53癌突变体Y220C、Y220N和Y220S

Cell Death & Disease

IF9.6

2026-02-26

OAAI

Danai Mavridi; Julianne S. Funk; Dimitrios-Ilias Balourdas; Andreas Krämer; Raysa Khan Tareque; Oleg Timofeev; John Spencer; Thorsten Stiewe; Andreas C. Joerger

Removal of Toxic Metabolites—Chelation: Manganese Disorders 毒性代谢物的去除—螯合：锰障碍

Journal of Inherited Metabolic Disease

IF3.8

2025-11-02

OAAI

Hendrik Vogt; George E. Kostakis; Rupert Purchase; John Spencer; Karin Tuschl

A Review on Luminescent Benzoselenadiazole Derivatives: Comparison with Benzothiadiazoles, Properties, Applications, and Trends 《发光苯并硒二唑衍生物综述：与苯并噻二唑的比较、性质、应用及趋势》

CHEMISTRY-AN ASIAN JOURNAL

IF3.3

2025-06-01

OAAI

Neto, Brenno A. D.; Spencer, John; Lapis, Alexandre A. M.

Particle size effects on vapour uptake and release dynamics in metal-organic frameworks

CHEMICAL COMMUNICATIONS

IF4.2

2025-04-01

OAAI

Nicks, Joshua; Mudure, Cosmin; James, Jordan; McDougall, Alexander; Hughes, William O. H.; Spencer, John; Duren, Tina; Burrows, Andrew D.

Single enantiomer propeller-shaped polynuclear complexes as catalysts-proof-of-concept for enantioinduction in a Michael addition reaction 单一对映异构体螺旋桨状多核配合物作为催化剂：Michael加成反应中对映诱导的可行性证明

ROYAL SOCIETY OPEN SCIENCE

IF2.9

2025-03-27

OAAI

Maddocks, Joe; Mahesh, Mohan; Sampani, Stavroula I.; Dixon, Alexander C.; Nielsen, Christian D. -T.; Kumar, Prashant; Akien, Geoffrey R.; Spencer, John; Abdul-Sada, Alaa; Turner, John F. C.; Spivey, Alan C.; Kostakis, George E.

Novel mitochondrial-targeted alkyl chains act as fungal specific inhibitors of C. neoformans

FRONTIERS IN MICROBIOLOGY

IF4.5

2025-02-04

OAAI

Edrich, Elizabeth S. M.; Young, Luke; Spencer, John; Mcgown, Andrew; Moore, Anthony L.; Gourlay, Campbell W.

Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant Linkers 使用醛-炔-胺偶联产生药物化学相关的连接体

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2025-01-25

OAAI

Mcgown, Andrew; Vetma, Vesna; Crepin, Damien; Lin, Yan; Adcock, Claire; Craigon, Conner; Nafie, Jordan; von Emloh, Daniel; Sutton, Lea; Bailey, Kiera; Edmunds, Lewis; Sharma, Manvendra; Wilden, Jonathan D.; Coles, Simon J.; Tizzard, Graham J.; Farnaby, William; Ciulli, Alessio; Kostakis, George E.; Spencer, John

Synthesis of Core-Functionalised Naphthalenediimides from Naphthalenetetracarboxylic Dianhydride using a Vibratory Ball Mill: Bromination, Imidization and Heck-Type Reactions

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2025-01-23

PREAI

Dodson, E. M.; Lawson, T. E.; Lai-Morrice, J.; Emerit, H.; Guest, D. P.; Panther, L. A.; Gonzalez-Mendez, R.; Roe, S. M.; Goodall, C. A. I.; Bagley, M. C.; Spencer, J.; Greenland, B. W.

Characterization of the Active Enantiomer and Mapping of the Stereospecific Intermolecular Pattern of a Reference P2X7 Allosteric Antagonist 活性对映异构体的表征及参考P2X7别构拮抗剂立体特异性分子间模式的映射

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-01-22

PREAI

Mcgown, A; Renault, N; Barczyk, A; Nafie, J; Barluzzi, L; Guest, D; Tizzard, GJ; Coles, SJ; Leach, D; von Emloh, D; Sutton, L; Bailey, K; Edmunds, L; Greenland, BW; Millet, R; Spencer, J; Dezitter, X

Controlling the Uptake and Release of Semiochemicals in Channel-Type Metal-Organic Frameworks Through Pore Expansion

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2024-05-22

OAAI

Nicks, Joshua; Shearer, Greig C.; Paul-Taylor, Joseph; Lai-Morrice, James; Dadswell, Chris; Guest, Daniel; Hughes, William O. H.; Spencer, John; Dueren, Tina; Burrows, Andrew D.

Introduction to 'Medicinal Chemistry Small Molecule Probes'

RSC CHEMICAL BIOLOGY

IF3.1

2024-01-01

OAAI

Nixon, Gemma; Rahman, Khondaker Miraz; Spencer, John

Investigating the prevalence of pulmonary hypertension amongst individuals with heart failure: a systematic review and meta-analysis

THORAX

IF7.7

2023-11-06

OAAI

Khan, M.; Suribhatla, R.; Spencer, J.; Daniel, N.; Kartsonaki, C.

Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites

PHARMACEUTICS

IF5.5

2023-10-10

OAAI

Reyser, Thibaud; Paloque, Lucie; Nguyen, Michel; Augereau, Jean-Michel; Fuchter, Matthew John; Lopez, Marie; Arimondo, Paola B.; Hassell-Hart, Storm; Spencer, John; Di Stefano, Luisa; Benoit-Vical, Francoise

A change of direction through trans-bis-silylation of alkynes

NATURE SYNTHESIS

IF20

2023-06-22

PREAI

Spencer, John

Chirality: a key parameter in chemical probes

RSC CHEMICAL BIOLOGY

IF3.1

2023-01-01

OAAI

McGown, Andrew; Nafie, Jordan; Otayfah, Mohammed; Hassell-Hart, Storm; Tizzard, Graham J. J.; Coles, Simon J. J.; Banks, Rebecca; Marsh, Graham P. P.; Maple, Hannah J. J.; Kostakis, George E. E.; Silvestri, Ilaria Proietti; Colbon, Paul; Spencer, John

Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction

ORGANIC LETTERS

IF5

2022-10-20

OAAI

Hassell-Hart, Storm; Speranzini, Elisa; Srikwanjai, Sirihathai; Hossack, Euan; Roe, S. Mark; Fearon, Daren; Akinbosede, Daniel; Hare, Stephen; Spencer, John

A Convenient, Rapid, Conventional Heating Route to MIDA Boronates

MOLECULES

IF4.6

2022-08-09

OAAI

McGown, Andrew; Edmonds, Anthony K.; Guest, Daniel; Holmes, Verity L.; Dadswell, Chris; Gonzalez-Mendez, Ramon; Goodall, Charles A., I; Bagley, Mark C.; Greenland, Barnaby W.; Spencer, John

Solvent-Free Synthesis of Core-Functionalised Naphthalene Diimides by Using a Vibratory Ball Mill: Suzuki, Sonogashira and Buchwald-Hartwig Reactions

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2022-07-13

OAAI

Panther, Lydia A.; Guest, Daniel P.; McGown, Andrew; Emerit, Hugo; Tareque, Raysa Khan; Jose, Arathy; Dadswell, Chris M.; Coles, Simon J.; Tizzard, Graham J.; Gonzalez-Mendez, Ramon; Goodall, Charles A., I; Bagley, Mark C.; Spencer, John; Greenland, Barnaby W.

研究方向