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收藏分享 收藏 Switching to biological DMARDs versus cycling among JAK inhibitors in patients with rheumatoid arthritis and with inadequate response to JAK inhibitors: from FIRST registry将生物DMARDs与JAK抑制剂序贯疗法用于对JAK抑制剂应答不足的类风湿关节炎患者：来自FIRST注册研究
Miyazaki, Yusuke; Nakayamada, Shingo; Tanaka, Hiroaki; Hanami, Kentaro; Fukuyo, Shunsuke; Yamaguchi, Ayako; Miyagawa, Ippei; Satoh-Kanda, Yurie; Todoroki, Yasuyuki; Inoue, Yoshino; Ueno, Masanobu; Tanaka, Yoshiya 分享 收藏 LUPUS PATIENTS CAN BE CATEGORIZED INTO FOUR GROUPS BASED ON IMMUNOPHENOTYPE, EACH EXHIBITING DISTINCT RELAPSE RATES狼疮患者可根据免疫表型分为四组，每组表现出不同的复发率。Kubo, S.; Nakayamada, S.; Miyazaki, Y.; Todoroki, Y.; Ueno, M.; Kusaka, K.; Matsunaga, S.; Tanaka, H.; Ohkubo, N.; Sakai, H.; Miyagawa, I.; Hanami, K.; Tanaka, Y. 分享 收藏 Microgravity environment grown crystal structure information based engineering of direct electron transfer type glucose dehydrogenaseOkuda-Shimazaki, Junko; Yoshida, Hiromi; Lee, Inyoung; Kojima, Katsuhiro; Suzuki, Nanoha; Tsugawa, Wakako; Yamada, Mitsugu; Inaka, Koji; Tanaka, Hiroaki; Sode, Koji 分享 收藏 Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis多祖先全基因组关联分析确定类风湿关节炎的新遗传机制Ishigaki, Kazuyoshi; Sakaue, Saori; Terao, Chikashi; Luo, Yang; Sonehara, Kyuto; Yamaguchi, Kensuke; Amariuta, Tiffany; Too, Chun Lai; Laufer, Vincent A.; Scott, Ian C.; Viatte, Sebastien; Takahashi, Meiko; Ohmura, Koichiro; Murasawa, Akira; Hashimoto, Motomu; Ito, Hiromu; Hammoudeh, Mohammed; Al Emadi, Samar; Masri, Basel K.; Halabi, Hussein; Badsha, Humeira; Uthman, Imad W.; Wu, Xin; Lin, Li; Li, Ting; Plant, Darren; Barton, Anne; Orozco, Gisela; Verstappen, Suzanne M. M.; Bowes, John; MacGregor, Alexander J.; Honda, Suguru; Koido, Masaru; Tomizuka, Kohei; Kamatani, Yoichiro; Tanaka, Hiroaki; Tanaka, Eiichi; Suzuki, Akari; Maeda, Yuichi; Yamamoto, Kenichi; Miyawaki, Satoru; Xie, Gang; Zhang, Jinyi; Amos, Christopher, I; Keystone, Edward; Wolbink, Gertjan; Van der Horst-Bruinsma, Irene; Cui, Jing; Liao, Katherine P.; Carroll, Robert J.; Lee, Hye-Soon; Bang, So-Young; Siminovitch, Katherine A.; de Vries, Niek; Alfredsson, Lars; Rantapaa-Dahlqvist, Solbritt; Karlson, Elizabeth W.; Bae, Sang-Cheol; Kimberly, Robert P.; Edberg, Jeffrey C.; Mariette, Xavier; Huizinga, Tom; Dieude, Philippe; Schneider, Matthias; Kerick, Martin; Denny, Joshua C.; Matsuda, Koichi; Matsuo, Keitaro; Mimori, Tsuneyo; Matsuda, Fumihiko; Fujio, Keishi; Tanaka, Yoshiya; Kumanogoh, Atsushi; Traylor, Matthew; Lewis, Cathryn M.; Eyre, Stephen; Xu, Huji; Saxena, Richa; Arayssi, Thurayya; Kochi, Yuta; Ikari, Katsunori; Harigai, Masayoshi; Gregersen, Peter K.; Yamamoto, Kazuhiko; Bridges, S. Louis, Jr.; Padyukov, Leonid; Martin, Javier; Klareskog, Lars; Okada, Yukinori; Raychaudhuri, Soumya 分享 收藏 分享 收藏 Discovery and structure -activity relationships study of positive allosteric modulators of the M 3 muscarinic acetylcholine receptorTanaka, Hiroaki; Negoro, Kenji; Koike, Takanori; Tsukamoto, Issei; Yokoyama, Kazuhiro; Maeda, Jun; Inagaki, Yusuke; Shimoshige, Yukinori; Ino, Katsutoshi; Ishizu, Kenichiro; Takahashi, Taisuke 分享 收藏 分享 收藏 Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidaseSakamoto, Yasumitsu; Suzuki, Yoshiyuki; Nakamura, Akihiro; Watanabe, Yurie; Sekiya, Mizuki; Roppongi, Saori; Kushibiki, Chisato; Iizuka, Ippei; Tani, Osamu; Sakashita, Hitoshi; Inaka, Koji; Tanaka, Hiroaki; Yamada, Mitsugu; Ohta, Kazunori; Honma, Nobuyuki; Shida, Yosuke; Ogasawara, Wataru; Nakanishi-Matsui, Mayumi; Nonaka, Takamasa; Gouda, Hiroaki; Tanaka, Nobutada 分享 收藏 Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL OverexpressionTanaka, Hiroaki; Sakagami, Hideki; Kaneko, Naoki; Konagai, Satoshi; Yamamoto, Hiroko; Matsuya, Takahiro; Yuri, Masatoshi; Yamanaka, Yosuke; Mori, Masamichi; Takeuchi, Masahiro; Koshio, Hiroyuki; Hirano, Masaaki; Kuromitsu, Sadao 分享 收藏 Molecular screening of patients with FGFR alterations for phase 1 (ph1) study with the selective FGFR inhibitor Debio 1347Iafrate, Anthony J.; Borger, Darrell R.; Vivancos, Ana; Voss, Martin; Cleary, James; Meric-Bernstam, Funda; Tabernero, Josep; Flaherty, Keith; Ishii, Nobuya; Brichory, Franck; Tanaka, Hiroaki; Pokorska-Bocci, Anna; Baselga, Jose; Nuciforo, Paolo 分享 收藏 分享 收藏 Newton's cradle proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallographyNakamura, Akihiko; Ishida, Takuya; Kusaka, Katsuhiro; Yamada, Taro; Fushinobu, Shinya; Tanaka, Ichiro; Kaneko, Satoshi; Ohta, Kazunori; Tanaka, Hiroaki; Inaka, Koji; Higuchi, Yoshiki; Niimura, Nobuo; Samejima, Masahiro; Igarashi, Kiyohiko 分享 收藏 分享 收藏 Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificitySakamoto, Yasumitsu; Suzuki, Yoshiyuki; Iizuka, Ippei; Tateoka, Chika; Roppongi, Saori; Fujimoto, Mayu; Inaka, Koji; Tanaka, Hiroaki; Yamada, Mitsugu; Ohta, Kazunori; Gouda, Hiroaki; Nonaka, Takamasa; Ogasawara, Wataru; Tanaka, Nobutada 分享 收藏 ASP8273, a novel mutantselective irreversible EGFR inhibitor, inhibits growth of non-small cell lung cancer (NSCLC) cells with EGFR activating and T790M resistance mutationsSakagami, Hideki; Konagai, Satoshi; Yamamoto, Hiroko; Tanaka, Hiroaki; Matsuya, Takahiro; Mori, Masamichi; Koshio, Hiroyuki; Yuri, Masatoshi; Hirano, Masaaki; Kuromitsu, Sadao 分享 收藏 S46 Peptidases are the First Exopeptidases to be Members of Clan PASakamoto, Yasumitsu; Suzuki, Yoshiyuki; Iizuka, Ippei; Tateoka, Chika; Roppongi, Saori; Fujimoto, Mayu; Inaka, Koji; Tanaka, Hiroaki; Masaki, Mika; Ohta, Kazunori; Okada, Hirofumi; Nonaka, Takamasa; Morikawa, Yasushi; Nakamura, Kazuo T.; Ogasawara, Wataru; Tanaka, Nobutada 分享 收藏 Identification of a New Interaction Mode between the Src Homology 2 Domain of C-terminal Src Kinase (Csk) and Csk-binding Protein/Phosphoprotein Associated with Glycosphingolipid MicrodomainsTanaka, Hiroaki; Akagi, Ken-ichi; Oneyama, Chitose; Tanaka, Masakazu; Sasaki, Yuichi; Kanou, Takashi; Lee, Young-Ho; Yokogawa, Daisuke; Dobenecker, Marc-Werner; Nakagawa, Atsushi; Okada, Masato; Ikegami, Takahisa 分享 收藏 分享 收藏 
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