未登录 Targeting specific kinase substrates rescues increased colitis severity induced by the Crohn's disease-linked LRRK2-N2081D variant 靶向特定激酶底物可逆转克罗恩病相关LRRK2-N2081D变异引起的结肠炎严重程度加重 Heaton, George R.; Li, Xingjian; Li, Xianting; Zhou, Xiaoting; Zhang, Yuanxi; Vu, Duc Tung; Oeller, Marc; Karayel, Ozge; Hoang, Quyen Q.; Kars, Meltem Ece; Kamath, Nitika; Wang, Minghui; Tarassishin, Leonid; Mann, Matthias; Peter, Inga; Yue, Zhenyu 分享 收藏
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Longitudinal IgG antibody responses to Plasmodium vivax blood-stage antigens during and after acute vivax malaria in individuals living in the Brazilian Amazon Tashi, Tenzin; Upadhye, Aditi; Kundu, Prasun; Wu, Chunxiang; Menant, Sebastien; Soares, Roberta Reis; Ferreira, Marcelo U.; Longley, Rhea J.; Mueller, Ivo; Hoang, Quyen Q.; Tham, Wai-Hong; Rayner, Julian C.; Scopel, Kezia Kg; Lima-Junior, Josue C.; Tran, Tuan M. 分享 收藏
Allosteric differences dictate GroEL complementation of E. coli 变构差异决定了大肠杆菌的GroEL互补 Sivinski, Jared; Ngo, Duc; Zerio, Christopher J.; Ambrose, Andrew J.; Watson, Edmond R.; Kaneko, Lynn K.; Kostelic, Marius M.; Stevens, Mckayla; Ray, Anne-Marie; Park, Yangshin; Wu, Chunxiang; Marty, Michael T.; Hoang, Quyen Q.; Zhang, Donna D.; Lander, Gabriel C.; Johnson, Steven M.; Chapman, Eli 分享 收藏
A new alpha-synuclein missense variant (Thr72Met) in two Turkish families with Parkinson's disease 在两个患有帕金森氏病的土耳其家庭中，一种新的 α-突触核蛋白错义变体 (Thr72Met) Fevga, Christina; Park, Yangshin; Lohmann, Ebba; Kievit, Anneke J.; Breedveld, Guido J.; Ferraro, Federico; de Boer, Leon; van Minkelen, Rick; Hanagasi, Hasmet; Boon, Agnita; Wang, Wei; Petsko, Gregory A.; Hoang, Quyen Q.; Emre, Murat; Bonifati, Vincenzo 分享 收藏
Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL 大肠杆菌和ESKAPE病原体GroES/GroEL之间的功能差异 Sivinski, Jared; Ambrose, Andrew J.; Panfilenko, Iliya; Zerio, Christopher J.; Machulis, Jason M.; Mollasalehi, Niloufar; Kaneko, Lynn K.; Stevens, Mckayla; Ray, Anne-Marie; Park, Yangshin; Wu, Chunxiang; Hoang, Quyen Q.; Johnson, Steven M.; Chapman, Eli 分享 收藏
Development of a novel gene therapy for Fabry disease: Engineered alpha-galactosidase A transgene for improved stability Willer, Tobias; Hordeaux, Juliette; Tsai, Pai-Chi; Ellsworth, Daniel; Xu, Su; Eisenach, Helen; Shen, Jinsong; Louboutin, Jean-Pierre; Bell, Peter; Song, Chunjuan; Hoang, Quyen Q.; Gotschall, Russell; Weimer, Jill; Wilson, James M.; Do, Hung 分享 收藏
Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs Stevens, Mckayla; Howe, Chris; Ray, Anne-Marie; Washburn, Alex; Chitre, Siddhi; Sivinski, Jared; Park, Yangshin; Hoang, Quyen Q.; Chapman, Eli; Johnson, Steven M. 分享 收藏
Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics Wu, Chun-Xiang; Liao, Jingling; Park, Yangshin; Reed, Xylena; Engel, Victoria A.; Hoang, Neo C.; Takagi, Yuichiro; Johnson, Steven M.; Wang, Mu; Federici, Mark; Nichols, R. Jeremy; Sanishvili, Ruslan; Cookson, Mark R.; Hoang, Quyen Q. 分享 收藏
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Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus 羟基联苯酰胺GroEL/ES抑制剂是抗金黄色葡萄球菌浮游和生物膜形式的有效抗菌剂 Kunkle, Trent; Abdeen, Sanofar; Salim, Nilshad; Ray, Anne -Marie; Stevens, Mckayla; Ambrose, Andrew J.; Victorino, Jose; Park, Yangshin; Hoang, Quyen Q.; Chapman, Eli; Johnson, Steven M. 分享 收藏
Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1 Tashiro, Shinya; Caaveiro, Jose M. M.; Nakakido, Makoto; Tanabe, Aki; Nagatoishi, Satoru; Tamura, Yasushi; Matsuda, Noriyuki; Liu, Dali; Hoang, Quyen Q.; Tsumoto, Kouhei 分享 收藏
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA) Sulfonamido-2-arylbenzoxazole GroEL/ES抑制剂作为抗耐甲氧西林金黄色葡萄球菌 (MRSA) 的有效抗菌剂 Abdeen, Sanofar; Kunkle, Trent; Salim, Nilshad; Ray, Anne-Marie; Mammadova, Najiba; Summers, Corey; Stevens, Mckayla; Ambrose, Andrew J.; Park, Yangshin; Schultz, Peter G.; Horwich, Arthur L.; Hoang, Quyen Q.; Chapman, Eli; Johnson, Steven M. 分享 收藏
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Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites Liu, Ce Feng; Brandt, Gabriel S.; Hoang, Quyen Q.; Naumova, Natalia; Lazarevic, Vanja; Hwang, Eun Sook; Dekker, Job; Glimcher, Laurie H.; Ringe, Dagmar; Petsko, Gregory A. 分享 收藏
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Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein Wang, Wei; Nguyen, Linh T. T.; Burlak, Christopher; Chegini, Fariba; Guo, Feng; Chataway, Tim; Ju, Shulin; Fisher, Oriana S.; Miller, David W.; Datta, Debajyoti; Wu, Fang; Wu, Chun-Xiang; Landeru, Anuradha; Wells, James A.; Cookson, Mark R.; Boxer, Matthew B.; Thomas, Craig J.; Gai, Wei Ping; Ringe, Dagmar; Petsko, Gregory A.; Hoang, Quyen Q. 分享 收藏
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