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The XCL1/XCR1 axis is upregulated in type 1 diabetes and aggravates its pathogenesis XCL1/XCR1轴在1型糖尿病中上调,并加剧其病理发生。 Tondello, Camilla; Bender, Christine; Golden, Gregory J.; Puppe, Deborah; Blickberndt, Elisa; Bayer, Monika; Buchmann, Giulia K.; Pfeilschifter, Josef; Bachmann, Malte; Hintermann, Edith; Brandes, Ralf P.; Betts, Michael R.; Kroczek, Richard A.; Christen, Urs 分享 收藏
Blockade of neutrophil extracellular trap components ameliorates cholestatic liver disease in Mdr2 (Abcb4) knockout mice 阻断中性粒细胞胞外诱捕成分可改善Mdr2 (Abcb4) 基因敲除小鼠的胆汁淤积性肝病 Hintermann, Edith; Tondello, Camilla; Fuchs, Sina; Bayer, Monika; Pfeilschifter, Josef M.; Taubert, Richard; Mollenhauer, Martin; Elferink, Roland P. J. Oude; Manns, Michael P.; Christen, Urs 分享 收藏
Gene-expression profiling of laser-dissected islets and studies in deficient mice reveal chemokines as differential driving force of type 1 diabetes Bender, Christine; Mueller, Peter; Tondello, Camilla; Horn, Jessica; Holdener, Martin; Lasch, Stanley; Bayer, Monika; Pfeilschifter, Josef M.; Tacke, Frank; Ludwig, Andreas; Hansmann, Martin -Leo; Doring, Claudia; Hintermann, Edith; Christen, Urs 分享 收藏
Gut dysbiosis promotes islet-autoimmunity by increasing T-cell attraction in islets via CXCL10 chemokine Poysti, Sakari; Silojarvi, Satu; Brodnicki, Thomas C.; Catterall, Tara; Liu, Xin; Mackin, Leanne; Luster, Andrew D.; Kay, Thomas W. H.; Christen, Urs; Thomas, Helen E.; Hanninen, Arno 分享 收藏
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Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes Christen, Urs; Pouzol, Laetitia; Tunis, Melanie; Sassi, Anna; Tondello, Camilla; Bayer, Monika; Hintermann, Edith; Strasser, Daniel S.; Schuldes, Sabrina; Mentzel, Ulrich; Martinic, Marianne M. 分享 收藏
Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement Yesilyurt, Zeynep E.; Matthes, Jan; Hintermann, Edith; Castaneda, Tamara R.; Elvert, Ralf; Beltran-Ornelas, Jesus H.; Silva-Velasco, Diana L.; Xia, Ning; Kannt, Aimo; Christen, Urs; Centurion, David; Li, Huige; Pautz, Andrea; Arioglu-Inan, Ebru; Michel, Martin C. 分享 收藏
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Interleukin-22 in acute-on-chronic liver failure: A matter of ineffective levels, receptor dysregulation or defective signalling? Schwarzkopf, Katharina Maria; Eberle, Larissa; Uschner, Frank Erhard; Klein, Sabine; Schierwagen, Robert; Muecke, Marcus Maximilian; Schaefer, Liliana; Claria, Joan; Zeuzem, Stefan; Hintermann, Edith; Christen, Urs; Lange, Christian Markus; Trebicka, Jonel; Welsch, Christoph 分享 收藏
Ubiquitous antigen-specific T regulatory type 1 cells variably suppress hepatic and extrahepatic autoimmunity Umeshappa, Channakeshava Sokke; Mbongue, Jacques; Singha, Santiswarup; Mohapatra, Saswat; Yamanouchi, Jun; Lee, Justin A.; Nanjundappa, Roopa Hebbandi; Shao, Kun; Christen, Urs; Yang, Yang; Ellestad, Kristofor K.; Santamaria, Pere 分享 收藏
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Establishment of a new animal model for the acute-on-chronic liver failure Schwarzkopf, Katharina; Rueschenbaum, Sabrina; Muecke, Marcus Maximilian; Fuchs, Sina; Messmer, Marie; Bayer, Monika; Hintermann, Edith; Zeuzem, Stefan; Christen, Urs; Lange, Christian 分享 收藏