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H

Helena Käck

AstraZeneca
H指数:16
被引数:1,238

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Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction

基于片段的药物发现：Keap1-Nrf2蛋白-蛋白相互作用的新型高亲和力、选择性及抗炎抑制剂的发现

Angewandte Chemie International Edition
IF0
2025-08-210
OAAI
Chunyu Lin; Dilip Narayanan; Marilia Barreca; Cecilie Poulsen; Leandro Silva da Costa; Xiangrong Chen; Kendall G. Wichman; Cherisse A. Charley; Jaslin L. Lindsay; Mahya Dezfouli; Dimitra Vlissari; Thomas S. Mortensen; Camilla B. Chan; Jingyi Wang; William Richardson; Charlotte E. Manning; Zhuoyao Chen; Jie Zang; Helena Käck; Michael Gajhede; Alex N. Bullock; David J. Blake; David Olagnier; Prof. Anders Bach
Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl}carbonyl)cyclopropanecarboxylic Acid (AZD9898) as a New Treatment for Asthma
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-08-1513
PREAI
af Rosenschold, Magnus Munck; Johannesson, Petra; Nikitidis, Antonios; Tyrchan, Christian; Chang, Hui-Fang; Ronn, Robert; Chapman, Dave; Ullah, Victoria; Nikitidis, Grigorios; Glader, Pernilla; Kack, Helena; Bonn, Britta; Wagberg, Fredrik; Bjorkstrand, Eva; Andersson, Ulf; Swedin, Linda; Rohman, Mattias; Andreasson, Theresa; Bergstrom, Eva Lamm; Jiang, Fanyi; Zhou, Xiao-Hong; Lundqvist, Anders J.; Malmberg, Anna; Ek, Margareta; Gordon, Euan; Pettersen, Anna; Ripa, Lena; Davis, Andrew M.

研究方向

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L
Lisa Wissler
H 指数:17论文数:37被引数:934
L
Linda Öster
H 指数:18论文数:57被引数:866
C
Christian Tyrchan
H 指数:28论文数:139被引数:5,215
H
Hans Lönn
H 指数:19论文数:37被引数:1,667
K
Kevin Doyle
H 指数:19论文数:88被引数:1,374
L
Lena Ripa
H 指数:16论文数:27被引数:591
J
Jon Read
H 指数:34论文数:90被引数:3,686
F
Fredrik Edfeldt
H 指数:10论文数:19被引数:530
M
Magnus Munck af Rosenschöld
H 指数:2论文数:10被引数:26
E
Euan Gordon
H 指数:20论文数:61被引数:990