David Andrews - Publications, H-index & Citations

David Andrews

AstraZeneca

31H指数

117论文数

2.8K被引数

收录论文 24

发表时间

A Patient's Wish List for Imaging Artificial Intelligence (and Radiology)

JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY

IF5.1

2023-09-01

PREAI

Andrews, David

Design and Selection of Heterodimerizing Helical Hairpins for Synthetic Biology

ACS SYNTHETIC BIOLOGY

IF3.9

2023-05-24

OAAI

Smith, Abigail J. J.; Naudin, Elise A. A.; Edgell, Caitlin L. L.; Baker, Emily G. G.; Mylemans, Bram; FitzPatrick, Laura; Herman, Andrew; Rice, Helen M. M.; Andrews, David M. M.; Tigue, Natalie; Woolfson, Derek N. N.; Savery, Nigel J. J.

Identification and optimization of a novel series of selective PIP5K inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2022-01-01

OAAI

Andrews, David M.; Cartic, Sharon; Cosulich, Sabina; Divecha, Nullin; Faulder, Paul; Flemington, Vikki; Kern, Oliver; Kettle, Jason G.; MacDonald, Ellen; McKelvie, Jennifer; Pike, Kurt G.; Roberts, Bryan; Rowlinson, Rachel; Smith, James M.; Stockley, Martin; Swarbrick, Martin E.; Treinies, Iris; Waring, Michael J.

From peptides to proteins: coiled-coil tetramers to single-chain 4-helix bundles

CHEMICAL SCIENCE

IF7.4

2022-01-01

OAAI

Naudin, Elise A.; Albanese, Katherine, I; Smith, Abigail J.; Mylemans, Bram; Baker, Emily G.; Weiner, Orion D.; Andrews, David M.; Tigue, Natalie; Savery, Nigel J.; Woolfson, Derek N.

Rethinking Patient Consent in the Era of Artificial Intelligence and Big Data

JOURNAL OF THE AMERICAN COLLEGE OF RADIOLOGY

IF5.1

2021-01-01

PREAI

Kotsenas, Amy L.; Balthazar, Patricia; Andrews, David; Geis, J. Raymond; Cook, Tessa S.

Query-guided protein-protein interaction inhibitor discovery

CHEMICAL SCIENCE

IF7.4

2021-01-01

OAAI

Celis, Sergio; Hobor, Fruzsina; James, Thomas; Bartlett, Gail J.; Ibarra, Amaurys A.; Shoemark, Deborah K.; Hegedus, Zsofia; Hetherington, Kristina; Woolfson, Derek N.; Sessions, Richard B.; Edwards, Thomas A.; Andrews, David M.; Nelson, Adam; Wilson, Andrew J.

Discovery of AZD0364, a potent and selective oral inhibitor of ERK1/2 that is efficacious in both monotherapy and combination therapy in models of NSCLC

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Simpson, Iain; Anderton, Mark J.; Andrews, David M.; Breed, Jason; Davies, Emma; Debreczeni, Judit E.; Flemington, Vikki; Gibbons, Francis D.; Graham, Mark A.; Hopcroft, Philip; Howard, Tina; Hudson, Julian; Jones, Clifford D.; Jones, Christopher; Lindsay, Nicola; Pease, J. Elizabeth; Rawlins, Philip; Roberts, Karen; Swallow, Steve; St-Gallay, Steve; Tonge, Michael E.; Ward, Richard A.

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily

ACS CHEMICAL BIOLOGY

IF3.8

2017-11-28

OAAI

Wrigley, Jonathan D.; Gavory, Gerald; Simpson, Iain; Preston, Marian; Plant, Helen; Bradley, Jenna; Goeppert, Anne U.; Rozycka, Ewelina; Davies, Gareth; Walsh, Jarrod; Valentine, Andrea; McClelland, Keeva; Odrzywol, Krzysztofa Ewa; Renshaw, Jonathan; Boros, Joanna; Tart, Jonathan; Leach, Lindsey; Nowak, Thorsten; Ward, Richard A.; Harrison, Timothy; Andrews, David M.

Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-08-10

OAAI

Igoe, Niall; Bayle, Elliott D.; Tallant, Cynthia; Fedorov, Oleg; Meier, Julia C.; Savitsky, Pavel; Rogers, Catherine; Morias, Yannick; Scholze, Sarah; Boyd, Helen; Cunoosarny, Danen; Andrews, David M.; Cheasty, Anne; Brennan, Paul E.; Mueller, Susanne; Knapp, Stefan; Fish, Paul V.

Design of a Biased Potent Small Molecule Inhibitor of the Bromodonnain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-01-09

OAAI

Igoe, Niall; Bayle, Elliott D.; Fedorov, Oleg; Tallant, Cynthia; Savitsky, Pavel; Rogers, Catherine; Owen, Dafydd R.; Deb, Gauri; Somervaille, Tim C. P.; Andrews, David M.; Jones, Neil; Cheasty, Anne; Ryder, Hamish; Brennan, Paul E.; Mueller, Susanne; Knapp, Stefan; Fish, Paul V.

The creation and characterisation of a National Compound Collection: the Royal Society of Chemistry pilot

CHEMICAL SCIENCE

IF7.4

2016-01-01

OAAI

Andrews, David M.; Broad, Laura M.; Edwards, Paul J.; Fox, David N. A.; Gallagher, Timothy; Garland, Stephen L.; Kidd, Richard; Sweeney, Joseph B.

Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-10-07

156

PREAI

De Savi, Chris; Bradbury, Robert H.; Rabow, Alfred A.; Norman, Richard A.; de Almeida, Camila; Andrews, David M.; Ballard, Peter; Buttar, David; Callis, Rowena J.; Currie, Gordon S.; Curwen, Jon O.; Davies, Chris D.; Donald, Craig S.; Feron, Lyman J. L.; Gingell, Helen; Glossop, Steven C.; Hayter, Barry R.; Hussain, Syeed; Karoutchi, Galith; Lamont, Scott G.; MacFaul, Philip; Moss, Thomas A.; Pearson, Stuart E.; Tonge, Michael; Walker, Graeme E.; Weir, Hazel M.; Wilson, Zena

Compound Passport Service: supporting corporate collection owners in open innovation

DRUG DISCOVERY TODAY

IF7.5

2015-10-01

PREAI

Andrews, David M.; Degorce, Sebastien L.; Drake, David J.; Gustafsson, Magnus; Higgins, Kevin M.; Winter, Jon J.

Collaborative practices for medicinal chemistry research across the big pharma and not-for-profit interface

DRUG DISCOVERY TODAY

IF7.5

2014-04-01

PREAI

Andrews, David M.; Swarbrick, Martin E.; Merritt, Andrew T.

Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α-but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation

CHEMICAL COMMUNICATIONS

IF4.2

2014-01-01

PREAI

Waring, Michael J.; Andrews, David M.; Faulder, Paul F.; Flemington, Vikki; McKelvie, Jennifer C.; Maman, Sarita; Preston, Marian; Raubo, Piotr; Robb, Graeme R.; Roberts, Karen; Rowlinson, Rachel; Smith, James M.; Swarbrick, Martin E.; Treinies, Iris; Winter, Jon J. G.; Wood, Robert J.

Flexible and Scalable Route to HDAc Inhibitors Containing an Unusual Trisubstituted Pyridine Core

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2012-06-27

PREAI

Graham, Mark A.; Raw, Steven A.; Andrews, David M.; Good, Catherine J.; Matusiak, Zbigniew S.; Maybury, Mark; Stokes, Elaine S. E.; Turner, Andrew T.

Protein-Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2012-05-21

PREAI

Norman, Richard A.; Schott, Anne-Kathrin; Andrews, David M.; Breed, Jason; Foote, Kevin M.; Garner, Andrew P.; Ogg, Derek; Orme, Jonathon P.; Pink, Jennifer H.; Roberts, Karen; Rudge, David A.; Thomas, Andrew P.; Leach, Andrew G.

Depletion of anti-Galα1-3Gal antibody in baboons by specific α-Gal immunoaffinity columns

XENOTRANSPLANTATION

IF4.1

2007-07-02

102

PREAI

Kozlowski, T; Ierino, FL; Lambrigts, D; Foley, A; Andrews, D; Awwad, M; Monroy, R; Cosimi, AB; Cooper, DKC; Sachs, DH

Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-02-02

PREAI

Slater, Martin J.; Amphlett, Elizabeth M.; Andrews, David M.; Bravi, Gianpaolo; Burton, George; Cheasty, Anne G.; Corfield, John A.; Ellis, Malcolm R.; Fenwick, Rebecca H.; Fernandes, Stephanie; Guidetti, Rossella; Haigh, David; Hartley, C. David; Howes, Peter D.; Jackson, Deborah L.; Jarvest, Richard L.; Lovegrove, Victoria L. H.; Medhurst, Katrina J.; Parry, Nigel R.; Price, Helen; Shah, Pritom; Singh, Onkar M. P.; Stocker, Richard; Thommes, Pia; Wilkinson, Claire; Wonacott, Alan

CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates

AMERICAN JOURNAL OF TRANSPLANTATION

IF8.2

2004-09-01

176

OAAI

Kawai, T; Sogawa, H; Boskovic, S; Abrahamian, G; Smith, RN; Wee, SL; Andrews, D; Nadazdin, O; Koyama, I; Sykes, M; Winn, HJ; Colvin, RB; Sachs, DH; Cosimi, AB

研究方向