Richard B. Pouw - Publications, H-index & Citations

Richard B. Pouw

university of amsterdam

14H指数

63论文数

775被引数

收录论文 35

发表时间

Complement Factor H-Based Therapeutics: A Comprehensive Overview 补体因子H为基础的治疗方法：全面概述

European Journal of Immunology

IF3.7

2026-09-29

OAAI

Sebastiaan M. W. R. Hamers; Emmy J. Buter; Richard B. Pouw

Innate immune response to AAV-based gene therapy vectors: mechanisms of complement activation and cytokine release AAV基基因治疗载体的先天免疫反应：补体激活和细胞因子释放的机制

Molecular Therapy Methods & Clinical Development

IF4.7

2025-08-12

OAAI

Rebecca Xicluna; Petra C. Schwalie; Emma Bell; Desiree Von Tell; Guido Steiner; Emily Seeger; Julian J. Freen-van Heeren; Annelies W. Turksma; Richard B. Pouw; Timo Schwandt; Michael B. Otteneder; Theo Rispens; Mieke C. Brouwer; Cristina Bertinetti-Lapatki; Hélène Haegel

Post-translationally modified proteins bind and activate complement with implications for cellular uptake and autoantibody formation 翻译后修饰的蛋白质能够结合并激活补体，这关系到细胞摄取和自身抗体的形成。

Journal of Autoimmunity

IF7

2025-06-23

OAAI

M.D. van den Beukel; L. Zhang; S. van der Meulen; N.V. Borggreven; S. Nugteren; M.C. Brouwer; R.B. Pouw; K.A. Gelderman; A.H. de Ru; G.M.C. Janssen; P.A. van Veelen; R. Knevel; P.W.H.I. Parren; L.A. Trouw

Vesiculation as potential novel pathogenic mechanism in autoimmune hemolytic anemia 囊泡化作为自身免疫性溶血性贫血中一种潜在的新型致病机制

TRANSFUSION

IF2

2025-05-12

OAAI

de Boer, Esther C. W.; Mulder, Femke V. M.; Neri, Silvia; Wiskerke-van Stuijvenberg, Marije; Arts, Janine J. G.; Tol, Simon; Beuger, Boukje; Bosman, Matthieu C. J.; Thielen, Noortje; van der Griend, Rene; Folman, Claudia C.; de Haas, Masja; van Bruggen, Robin; Pouw, Richard B.; Vos, Josephine M. I.

SCIENTIFIC REPORTS

IF3.9

2025-03-28

OAAI

Veuskens, Bert R. J.; Brouwer, Mieke C.; van Mierlo, Gerard; Geissler, Judy; van Leeuwen, Karin; Derlagen, Maaike; Keijzer, Nadia C. H.; Hoogenboezem, Mark; Kuijpers, Taco W.; Pouw, Richard B.

Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5 新型ELISAs的开发与表征：用于因子H相关蛋白2、3、4和5的特异性定量

JOURNAL OF INNATE IMMUNITY

IF3

2025-03-26

OAAI

van Rossum, Mara; Veuskens, Bert R. J.; Brouwer, Mieke C.; van Mierlo, Gerard; Lucientes-Continente, Laura; de Jorge, Elena Goicoechea; Uzonyi, Barbara; Matola, Alexandra T.; Jozsi, Mihaly; Mueller, Guenter; Meter-Arkema, Anita M.; Poppelaars, Felix; Pauly, Diana; Pouw, Richard B.; Toonen, Erik J. M.

Common Haplotypes within the Chromosome 1q31.3 Region Determine Systemic Concentrations of the Entire Complement Factor H Protein Family 染色体1q31.3区域内的常见单倍型决定了补体因子H蛋白家族的系统浓度

JOURNAL OF INNATE IMMUNITY

IF3

2025-03-26

OAAI

Veuskens, Bert R. J.; van Rossum, Mara; Cattenstart, Emi; Brouwer, Mieke C.; van Mierlo, Gerard; Geissler, Judy; van Leeuwen, Karin; Liu, Jin; Anstadt, Robert A.; Richards, Burt T.; Hageman, Gregory S.; Kuijpers, Taco W.; Toonen, Erik J. M.; Pouw, Richard B.

Decreased complement 4 and interleukin-10 as biomarkers in aqueous humour for non-exudative age-related macular degeneration: a case control study 非渗出性年龄相关性黄斑变性患者房水中补体4和白细胞介素-10作为生物标志物的病例对照研究

JOURNAL OF TRANSLATIONAL MEDICINE

IF7.5

2025-03-12

OAAI

Schikora, Juliane; Dort, Aaron; Wolf, Hannah N.; Jozsi, Mihaly; Pouw, Richard B.; Bertelmann, Thomas; Bahlmann, Dirk; van Oterendorp, Christian; Feltgen, Nicolas; Hoerauf, Hans; Pauly, Diana; Klemming, Jannis

Prognostic significance of serum complement activation, neutrophil extracellular traps and extracellular DNA in newly diagnosed epithelial ovarian cancer 新诊断的上皮性卵巢癌中血清补体激活、中性粒细胞胞外陷阱和细胞外DNA的预后意义

gynecologic oncology

IF4.1

2025-02-01

PREAI

Ricciuti, Jason; Liu, Qian; Khan, A. N. M. Nazmul H.; Joseph, Janine M.; Veuskens, Bert; Giridharan, Thejaswini; Suzuki, Sora; Emmons, Tiffany; Yaffe, Michael; Kuijpers, Taco W.; Jongerius, Ilse; Brouwer, Mieke; Pouw, Richard B.; Odunsi, Kunle; Frederick, Peter; Mager, Katherine LaVigne; Lele, Shashikant; Gaulin, Nicole; Hakim, Christiane; Edwards, Robert P.; Olawaiye, Alexander B.; Sukamanovich, Paniti; Taylor, Sarah; Elishaev, Esther; Zsiros, Emese; Modugno, Francesmary; Moysich, Kirsten; Segal, Brahm

Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage

FRONTIERS IN IMMUNOLOGY

IF5.9

2024-11-12

OAAI

van Beek, Anna E.; Jeanguenat, Hannah; Haberli, Cecile; Pouw, Richard B.; Lamers, Christina; Pal, Gabor; Gal, Peter; Schmidt, Christoph Q.; Ricklin, Daniel; Keiser, Jennifer

Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels

FRONTIERS IN IMMUNOLOGY

IF5.9

2023-09-13

OAAI

Golomingi, Murielle; Kohler, Jessie; Lamers, Christina; Pouw, Richard B.; Ricklin, Daniel; Dobo, Jozsef; Gal, Peter; Pal, Gabor; Kiss, Bence; Dopler, Arthur; Schmidt, Christoph Q.; Hardy, Elaissa Trybus; Lam, Wilbur; Schroeder, Verena

Complement-regulatory biomaterial coatings: Activity and selectivity profile of the factor H-binding peptide 5C6 补体调节生物材料涂层: h因子结合肽5C6的活性和选择性

ACTA BIOMATERIALIA

IF9.6

2023-01-01

OAAI

Bechtler, Clement; Koutsogiannaki, Sophia; Umnyakova, Ekaterina; Hamid, Amal; Gautam, Avneesh; Sarigiannis, Yiannis; Pouw, Richard B.; Lamers, Christina; Rabbani, Said; Schmidt, Christoph Q.; Lambris, John D.; Ricklin, Daniel

Evaluating the clinical utility of measuring levels of factor H and the related proteins

MOLECULAR IMMUNOLOGY

IF3

2022-11-01

OAAI

Banerjee, Pratiti; Veuskens, Bert; Goicoechea de Jorge, Elena; Jozsi, Mihaly; Baeumner, Antje J.; Steiner, Mark-Steven; Pouw, Richard B.; Toonen, Erik J. M.; Pauly, Diana; Poppelaars, Felix

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations CFHR3的变化通过控制因子H的浓度来确定对脑膜炎球菌病的易感性

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-09-01

OAAI

Kumar, Vikrant; Pouw, Richard B.; Autio, Matias, I; Sagmeister, Manfred G.; Phua, Zai Yang; Borghini, Lisa; Wright, Victoria J.; Hoggart, Clive; Pan, Bangfen; Tan, Antson Kiat Yee; Binder, Alexander; Brouwer, Mieke C.; Pinnock, Ellie; De Groot, Ronald; Hazelzet, Jan; Emonts, Marieke; van der Flier, Michiel; Reiter, Karl; Nothen, Markus M.; Hoffmann, Per; Schlapbach, Luregn J.; Bellos, Evangelos; Anderson, Suzanne; Secka, Fatou; Martinon-Torres, Federico; Salas, Antonio; Fink, Colin; Carrol, Enitan D.; Pollard, Andrew J.; Coin, Lachlan J.; Zenz, Werner; Wouters, Diana; Ang, Lay Teng; Hibberd, Martin L.; Levin, Michael; Kuijpers, Taco W.; Davila, Sonia

Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis 脑膜炎球菌病期间低水平的因子H家族蛋白表明全身过程，而不是脑膜炎奈瑟氏球菌的特异性耗竭

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-05-26

OAAI

van Beek, Anna E.; Pouw, Richard B.; Wright, Victoria J.; Sallah, Neneh; Inwald, David; Hoggart, Clive; Brouwer, Mieke C.; Galassini, Rachel; Thomas, John; Calvo-Bado, Leo; Fink, Colin G.; Jongerius, Ilse; Hibberd, Martin; Wouters, Diana; Levin, Michael; Kuijpers, Taco W.

Complement & disease: out of the shadow into the spotlight INTRODUCTION

SEMINARS IN IMMUNOPATHOLOGY

IF9.2

2021-11-24

OAAI

Ricklin, Daniel; Pouw, Richard B.

Tipping the balance: intricate roles of the complement system in disease and therapy 打破平衡: 补体系统在疾病和治疗中的复杂作用

SEMINARS IN IMMUNOPATHOLOGY

IF9.2

2021-10-26

OAAI

Pouw, Richard B.; Ricklin, Daniel

Sweet turning bitter: Carbohydrate sensing of complement in host defence and disease

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2020-12-23

OAAI

Hevey, Rachel; Pouw, Richard B.; Harris, Claire; Ricklin, Daniel

High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B (vol 9, 848, 2018)

FRONTIERS IN IMMUNOLOGY

IF5.9

2020-01-24

OAAI

Pouw, Richard B.; Gomez Delgado, Irene; Lopez Lera, Alberto; Rodriguez de Cordoba, Santiago; Wouters, Diana; Kuijpers, Taco W.; Sanchez-Corral, Pilar

Complement factor H contributes to mortality in humans and mice with bacterial meningitis 补体因子H与人类和小鼠细菌性脑膜炎的死亡率有关

JOURNAL OF NEUROINFLAMMATION

IF10.1

2019-12-28

OAAI

Kasanmoentalib, E. Soemirien; Seron, Mercedes Valls; Engelen-Lee, Joo Yeon; Tanck, Michael W.; Pouw, Richard B.; van Mierlo, Gerard; Wouters, Diana; Pickering, Matthew C.; van der Ende, Arie; Kuijpers, Taco W.; Brouwer, Matthijs C.; van de Beek, Diederik

研究方向