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E

Ellen Fritsche

DNTOX GmbH

50H指数
242论文数
6.9K被引数
收录论文 105
发表时间
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Integrating mechanistic data to contextualize in vivo apical observations using the developmental neurotoxicity in vitro battery整合机制数据以利用发育神经毒性体外组合方法对体内顶端观察结果进行背景化处理
errToxicological Sciences
IF4.1
err2026-07-29
err0
errOAAI
errBrianna L Jackson; Yaoxing Wu; Kian Afsharian; Christopher Schlosser; Angela H Hofstra; Laura M Minnema; Jördis Klose; Ellen Fritsche; Manasvinee Mayil Vahanan; Timothy J Shafer; Kelly E Carstens; Agnes L Karmaus
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Prioritizing chemicals for developmental neurotoxicity by integrating data from a new approach methods (NAMs) battery covering key cellular events in neurodevelopment通过整合覆盖神经发育关键细胞事件的新方法方法（NAMs）组合数据，对发育神经毒性化学物质进行优先排序
errNeurotoxicology
IF3.9
err2026-07-01
err0
PREAI
errHall, Laura A.; Hsieh, Jui-Hua; Marvel, Skylar W.; Behl, Mamta; Fritsche, Ellen; Koch, Katharina; Kreutz, Anna; Leist, Marcel; Muriana, Arantza; Shafer, Timothy J.; Stanko, Jason P.; Sills, Robert C.; Hogberg, Helena T.; McPherson, Christopher A.
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Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery神经发育疾病通路到发育神经毒性体外测试组合中关键神经发育过程的功能映射
errAdvanced Science
IF14.1
err2026-04-14
err0
errOAAI
errEliska Kuchovska; Kristina Bartmann; Georgea Raad; Mats Schade; Luiz Ladeira; Arif Dönmez; Jördis Klose; Nicolai Görts; Denis Polozij; Lynn-Christin Saborowski; Farina Bendt; Bernard Staumont; Liesbet Geris; Katharina Koch; Ellen Fritsche
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Early-stage quality—late-stage confidence: Neural induction quality control as a key to reproducible MEA-based neurotoxicity assays早期质量—晚期信心：神经诱导质量控制作为实现可重复MEA基神经毒性测定法的关键
errNeurotoxicology
IF3.9
err2026-03-20
err0
errOAAI
errIlka Scharkin; Jochen Dobner; Nadine Pierchala; Kristina Bartmann; Ulrike Hübenthal; Farina Bendt; Gabriele Brockerhoff; Andrea Rossi; Ellen Fritsche; Julia Tigges; Katharina Koch
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Bridging AI advancements with risk assessment needs: A journey towards effective use and regulatory acceptance将人工智能进步与风险评估需求相结合：迈向有效应用和监管接受之路
errToxicology
IF4.6
err2026-03-03
err0
PREAI
errSerhii Kolesnyk; Joyce de Paula Souza; Angela Bearth; Lothar Aicher; Martin F. Wilks; Axel Mosig; Ellen Fritsche
err分享
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Developmental neurotoxicity evaluation of di(2-ethylhexyl) phthalate (DEHP) and three alternative plasticizers in human neurospheres二(2-乙基己基)邻苯二甲酸酯(DEHP)及三种替代增塑剂在人类神经球中的发育神经毒性评价
errEnvironment International
IF9.7
err2025-12-15
err0
errOAAI
errBritta A. Kühne; Jördis Klose; Bettina Seeger; Miriam Illa; Diego Muñoz-Torrero; Katharina Koch; Ellen Fritsche; Marta Barenys
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Report on the European Partnership for Alternative Approaches to Animal Testing (EPAA) “New Approach Methodology (NAMs) User Forum”, 30 – 31 October 2024, Helsinki, Finland关于欧洲替代动物测试方法伙伴关系（EPAA）“新方法学（NAMs）用户论坛”的报告，2024年10月30-31日，芬兰赫尔辛基
errRegulatory Toxicology and Pharmacology
IF3.5
err2025-10-24
err0
errOAAI
errMark T.D. Cronin; Sophie Cable; Christian Desaintes; Sylvia E. Escher; Ellen Hessel; Ellen Fritsche; Petra Kern; Gavin Maxwell; Gladys Ouedraogo; Tomasz Sobanski; Matthias Wehr; Andrew White
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The Cost Outcome Pathway framework: Integrating socio-economic impacts to Adverse Outcome Pathways for supporting policy makers成本结果路径框架：将社会经济影响整合到不良结果路径中以支持政策制定者
errToxicology
IF4.6
err2025-07-02
err0
errOAAI
errThibaut Coustillet; Angela Bearth; Xavier Coumoul; Anne-Sophie Villégier; Michèle Bisson; Ellen Fritsche; Jean-Marc Brignon; Florence Zeman; Karine Audouze
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Developmental neurotoxicity as a case example for a six-step framework for the sustainable regulatory implementation of NAMs发育神经毒性作为NAMs可持续监管实施六步框架的案例示例
errCURRENT OPINION IN TOXICOLOGY
IF3.6
err2025-06-01
err0
PREAI
errJonathan Blum; Kristina Bartmann; Joyce de Paula Souza; Ellen Fritsche
err分享
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A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays体外筛选试验基准浓度建模的生物统计学流程比较研究
errComputational Toxicology
IF2.9
err2025-05-30
err0
PREAI
errKelly E. Carstens; Arif Dönmez; Jui-Hua Hsieh; Kristina Bartmann; Katie Paul Friedman; Katharina Koch; Martin Scholze; Ellen Fritsche
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Nuclear hormone receptors control fundamental processes of human fetal neurodevelopment: Basis for endocrine disruption assessment核激素受体调控人类胎儿神经发育的基本过程：内分泌干扰评估的基础
errENVIRONMENT INTERNATIONAL
IF9.7
err2025-04-01
err2
errOAAI
errKoch, Katharina; Schlueppmann, Kevin; Huesken, Saskia; Stark, Louisa Merit; Foerster, Nils; Masjosthusmann, Stefan; Klose, Jordis; Doenmez, Arif; Fritsche, Ellen
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Editorial: Five grand challenges in toxicology
errFRONTIERS IN TOXICOLOGY
IF4.6
err2025-01-21
err0
errOAAI
errFadeel, Bengt; Alexander, Jan; Antunes, Sara C.; Dalhoff, Kim; Fritsche, Ellen; Hogberg, Helena T.; Huaux, Francois; Oredsson, Stina; Pietroiusti, Antonio; Svingen, Terje; Wilks, Martin F.
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The Long Way from Raw Data to NAM-Based Information: Overview on Data Layers and Processing Steps从原始数据到NAM（名称）基础信息的漫长路径：数据层和加工步骤概述
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err3
errOAAI
errBlum, J; Brüll, M; Hengstler, JG; Dietrich, DR; Gruber, AJ; Dipalo, M; Kraushaar, U; Mangas, I; Terron, A; Fritsche, E; Marx-Stoelting, P; Hardy, B; Schepky, A; Escher, SE; Hartung, T; Landsiedel, R; Odermatt, A; Sachana, M; Koch, K; Dönmez, A; Masjosthusmann, S; Bothe, K; Schildknecht, S; Beilmann, M; Beltman, JB; Fitzpatrick, S; Mangerich, A; Rehm, M; Tangianu, S; Zickgraf, FM; Kamp, H; Burger, G; van de Water, B; Kleinstreuer, N; White, A; Leist, M
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Mapping Out Strategies to Further Develop Human-Relevant New Approach Methodology (NAM)- Based Developmental Neurotoxicity (DNT) Testing制定进一步发展基于人类相关性新方法学(NAM)的发育神经毒性(DNT)测试的策略
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err2
errOAAI
errCöllen, E; Bartmann, K; Blum, J; Carstens, K; Celardo, I; Chatterjee, N; Corvaro, M; Dreser, N; Fritsche, E; Hartung, T; Hogberg, HT; Knudsen, T; Koch, K; Kreutz, A; Lislien, M; Magel, V; Marty, MS; Pallocca, G; Bal-Price, A; Rovida, C; Sachana, M; Shafer, TJ; Smirnova, L; Suciu, I; Tanaskov, Y; Tangianu, S; Wolfbeisz, C; Leist, M
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Developmental Neurotoxicity (DNT): A Call for Implementation of New Approach Methodologies for Regulatory Purposes: Summary of the 5th International Conference on DNT Testing发育神经毒性（DNT）：呼吁实施新的方法学以用于监管目的：第5届国际发育神经毒性测试会议总结
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err2
errOAAI
errCelardo, I; Aschner, M; Ashton, RS; Carstens, KE; Cediel-Ulloa, A; Cöllen, E; Crofton, KM; Debad, SJ; Dreser, N; Fitzpatrick, S; Fritsche, E; Gutsfeld, S; Hardy, B; Hartung, T; Hessel, E; Heusinkveld, H; Hogberg, HT; Hsieh, JH; Kanda, Y; Knight, GT; Knudsen, T; Koch, K; Kuchovska, E; Mangas, I; Marty, MS; Melching-Kollmuss, S; Müller, I; Müller, P; Myhre, O; Paparella, M; Pitzer, E; Bal-Price, A; Sachana, M; Schlüppmann, K; Shafer, TJ; Schäfer, J; Smirnova, L; Tal, T; Tanaskov, Y; Tangianu, S; Testa, G; Ückert, AK; Whelan, M; Leist, M
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The SCAHT Adverse Outcome Pathway (AOP)_HUB: A Hands-on Platform for Information Exchange, Sharing, and Developing AOPsSCAHT 不良结局通路 (AOP)_HUB：一个用于信息交流、共享和开发 AOP 的实践平台
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err0
errOAAI
errCoerek, E; Kuchovska, E; Gerner, L; Nilma, L; Villeneuve, D; Fritsche, E
err分享
err收藏
Mapping Physiology: A Systems Biology Approach for the Development of Alternative Methods in Toxicology映射生理学：一种用于毒理学替代方法开发的系统生物学方法
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err0
errOAAI
errStaumont, B; Ladeira, L; Gamba, A; Heusinkveld, HJ; Piersma, A; Fritsche, E; Masereeuw, R; Vanhaecke, T; Teunis, M; Luechtefeld, TH; Hartung, T; Jover, R; Vinken, M; Geris, L
err分享
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Transcriptomic characterization of 2D and 3D human induced pluripotent stem cell-based in vitro models as New Approach Methodologies for developmental neurotoxicity testing
errTOXICOLOGY
IF4.6
err2025-01-01
err0
PREAI
errLislien, Malene; Kuchovska, Eliska; Kapr, Julia; Duale, Nur; Andersen, Jill Mari; Dirven, Hubert; Myhre, Oddvar; Fritsche, Ellen; Koch, Katharina; Wojewodzic, Marcin W.
err分享
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Addressing uncertainties in the DNT in vitro battery (DNT IVB) by incorporating glial models and increasing human relevance
errTOXICOLOGY LETTERS
IF2.9
err2024-09-01
err0
PREAI
errKoch, K.; Zuehr, E.; Bartmann, K.; Guzzo, R.; Lilikumar, A. S. Cheruvil; Stark, L.; Egger, I.; Myhre, O.; Fritsche, E.
err分享
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HiPSC-derived 3D neural models reveal neurodevelopmental pathomechanisms of the Cockayne Syndrome BHiPSC衍生的3D神经模型揭示了Cockayne综合征B的神经发育病理机制
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-08-23
err1
errOAAI
errKapr, Julia; Scharkin, Ilka; Ramachandran, Haribaskar; Westhoff, Philipp; Pollet, Marius; Dangeleit, Selina; Brockerhoff, Gabriele; Rossi, Andrea; Koch, Katharina; Krutmann, Jean; Fritsche, Ellen
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研究方向

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