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A novel ex vivo protocol that mimics length and excitation changes of human muscles during walking induces force losses in EDL but not in soleus of mdx mice 一种模拟人类肌肉在行走过程中长度和兴奋性变化的离体新方案，可导致mdx小鼠的EDL肌肉出现力损失，但不会对soleus肌肉产生影响。 Hu, Xiao; McCrady, Allison N.; Bukovec, Katherine E.; Yuan, Claire; Miller, Emily Y.; Bour, Rachel K.; Bruce, Anthony C.; Crump, Katherine B.; Peirce, Shayn M.; Grange, Robert W.; Blemker, Silvia S. 分享 收藏
Neuromuscular Dysfunction Precedes Cognitive Impairment in a Mouse Model of Alzheimer's Disease Brisendine, Matthew H.; Nichenko, Anna S.; Bandara, Aloka B.; Willoughby, Orion S.; Amiri, Niloufar; Weingrad, Zach; Specht, Kalyn S.; Bond, Jacob M.; Addington, Adele; Jones III, Ronald G.; Murach, Kevin A.; Poelzing, Steven; Craige, Siobhan M.; Grange, Robert W.; Drake, Joshua C. 分享 收藏
Prolonged voluntary wheel running reveals unique adaptations in mdx mice treated with microdystrophin constructs ± the nNOS-binding site Hamm, S. E.; Yuan, C.; McQueen, L. F.; Wallace, M. A.; Zhang, H.; Arora, A.; Garafalo, A. M.; McMillan, R. P.; Lawlor, M. W.; Prom, M. J.; Ott, E. M.; Yan, J.; Addington, A. K.; Morris, C. A.; Gonzalez, J. P.; Grange, R. W. 分享 收藏
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AAV-Mediated Gene Transfer Restores a Normal Muscle Transcriptome in a Canine Model of X-Linked Myotubular Myopathy Dupont, Jean-Baptiste; Guo, Jianjun; Renaud-Gabardos, Edith; Poulard, Karine; Latournerie, Virginie; Lawlor, Michael W.; Grange, Robert W.; Gray, John T.; Buj-Bello, Ana; Childers, Martin K.; Mack, David L. 分享 收藏
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Systemic AAV8-Mediated Gene Therapy Drives Whole-Body Correction of Myotubular Myopathy in Dogs Mack, David L.; Poulard, Karine; Goddard, Melissa A.; Latoumerie, Virginie; Snyder, Jessica M.; Grange, Robert W.; Elverman, Matthew R.; Denard, Jerome; Veron, Philippe; Buscara, Laurine; Le Bec, Christine; Hogrel, Jean-Yves; Brezovec, Annie G.; Meng, Hui; Yang, Lin; Liu, Fujun; O'Callaghan, Michael; Gopal, Nikhil; Kelly, Valerie E.; Smith, Barbara K.; Strande, Jennifer L.; Mavilio, Fulvio; Beggs, Alan H.; Mingozzi, Federico; Lawlor, Michael W.; Buj-Bello, Ana; Childers, Martin K. 分享 收藏
Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points Capogrosso, Roberta Francesca; Mantuano, Paola; Cozzoli, Anna; Sanarica, Francesca; Massari, Ada Maria; Conte, Elena; Fonzino, Adriano; Giustino, Arcangela; Rolland, Jean-Francois; Quaranta, Angelo; De Bellis, Michela; Camerino, Giulia Maria; Grange, Robert W.; De Luca, Annamaria 分享 收藏
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Prolonged Benefit from Systemic rAAV8 in a Canine Model of Myotubular Myopathy Elverman, Matthew; Mack, David; Goddard, Melissa; Snyder, Jessica; Grange, Robert; Poulard, Karine; Latournerie, Virginie; Veron, Philippe; Buscara, Laurine; Le Bec, Christine; Martin, Samia; Mavilio, Fulvio; Mingozzi, Federico; Meng, Hui; Lawlor, Michael; Beggs, Alan; Buj-Bello, Anna; Childers, Martin 分享 收藏
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Minimally Effective Dose of Systemic AAV8-MTM1 Needed To Prolong Survival and Correct Severe Muscle Pathology in a Canine Model of X-Linked Myotubular Myopathy Mack, David L.; Poulard, Karine; Goddard, Melissa; Snyder, Jessica M.; Grange, Robert W.; Doering, Jon; Czerniecki, Stefan; Strande, Jennifer L.; Latournerie, Virginie; Veron, Philippe; Meng, Hui; Yang, Lin; Liu, Fujun; Le Bec, Christine; Buscara, Laurine; Martin, Samia; Moullier, Philippe; O'Callaghan, Michael; Mingozzi, Federico; Beggs, Alan H.; Lawlor, Michael W.; Buj-Bello, Anna; Mavilio, Fulvio; Childers, Martin K. 分享 收藏
Sustained Expression of a Canine Micro-Dystrophin Lead To Improvement of Limb Muscle Function in Dystrophic Dogs Following Large Scale AAV-Mediated Treatment Halbert, Christine; Goddard, Melissa; Lee, Donghoon; Mack, David; Butts, Tiffany; Grange, Robert; Johnson, Mackenzie; Storb, Rainer; Miller, Dusty; Chamberlain, Jeffrey; Tapscott, Stephen; Childers, Martin; Wang, Zejing 分享 收藏
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