Kwang Chul Chung

Yonsei University

H指数:44

被引数:6,006

个人简介

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DAPK1-Mediated Parkin Inactivation Enhances Neurotoxicity via MITOL-Dependent Degradation

DAPK1介导的Parkin失活通过MITOL依赖性降解增强神经毒性

Journal of Cellular and Molecular Medicine

IF4.2

2026-04-060

Ubiquitin-Specific Protease 20 Promotes CCCP-Induced Mitophagy Through Deubiquitination and Stabilization of Serine/Threonine Protein Kinase PINK1

泛素特异性蛋白酶20通过去泛素化和稳定丝氨酸/苏氨酸蛋白激酶PINK1促进CCCP诱导的线粒体自噬

Journal of Molecular Neuroscience

IF2.7

2025-12-130

OAAI

Ubiquitin-specific protease 7 promotes the growth and oncogenic potential of acute myeloid leukemia cells through the deubiquitination and upregulation of LRRK2

泛素特异性蛋白酶7通过LRRK2的去泛素化和上调促进急性髓系白血病细胞的生长和致癌潜能。

Journal of Biological Chemistry

IF3.9

2025-09-020

OAAI

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway

Gintonin 通过 Nrf2/HO-1 通路减轻 MPTP 诱导的黑质纹状体多巴胺能神经元丢失及 α-突触核蛋白积聚

MOLECULAR NEUROBIOLOGY

IF4.3

2024-04-160

The SCF-FBW7β E3 ligase mediates ubiquitination and degradation of the serine/threonine protein kinase PINK1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-011

OAAI

Dual-specificity kinase DYRK3 phosphorylates p62 at the Thr-269 residue and promotes melanoma progression

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-011

OAAI

E3 ligase adaptor FBXO7 contributes to ubiquitination and proteasomal degradation of SIRT7 and promotes cell death in response to hydrogen peroxide

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-03-0112

OAAI

DYRK3 phosphorylates SNAPIN to regulate axonal retrograde transport and neurotransmitter release

CELL DEATH DISCOVERY

IF7

2022-12-304

OAAI

Covalent conjugation of ubiquitin-like ISG15 to apoptosis- inducing factor exacerbates toxic stimuli-induced apoptotic cell death

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-10-013

OAAI

The ubiquitin-proteasome system and autophagy mutually interact in neurotoxin-induced dopaminergic cell death models of Parkinson's disease

FEBS LETTERS

IF3

2022-09-036

PRE

FBXO7 triggers caspase 8-mediated proteolysis of the transcription factor FOXO4 and exacerbates neuronal cytotoxicity

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-12-018

OAAI

Protein phosphatase PPM1B inhibits DYRK1A kinase through dephosphorylation of pS258 and reduces toxic tau aggregation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-0114

OAAI

Human telomerase reverse transcriptase positively regulates mitophagy by inhibiting the processing and cytoplasmic release of mitochondrial PINK1

CELL DEATH & DISEASE

IF9.6

2020-06-0826

OAAI

Covalent ISG15 conjugation to CHIP promotes its ubiquitin E3 ligase activity and inhibits lung cancer cell growth in response to type I interferon

CELL DEATH & DISEASE

IF9.6

2018-01-2445

OAAI

The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death

泛素E3连接酶芯片在星形孢菌素诱导的细胞死亡过程中促进丝氨酸/苏氨酸蛋白激酶PINK1的蛋白酶体降解

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-01-0130

OAAI

Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression (vol 8, pg 54, 2015)

MOLECULAR BRAIN

IF2.9

2017-10-060

OAAI

Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

FRONTIERS IN CELLULAR NEUROSCIENCE

IF4

2017-05-1120

OAAI

Estradiol Synthesis in Gut-Associated Lymphoid Tissue: Leukocyte Regulation by a Sexually Monomorphic System

ENDOCRINOLOGY

IF3.3

2016-10-259

OAAI

Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation

HUMAN MOLECULAR GENETICS

IF3.2

2016-10-2529

OAAI

Proteolytic degradation and potential role of onconeural protein cdr2 in neurodegeneration

CELL DEATH & DISEASE

IF9.6

2016-06-0211

OAAI

Kwang Chul Chung

个人简介

教育背景

工作经历

荣誉奖项

研究方向