Tae-Sung Koo

chungnam national university

H指数:18

被引数:906

个人简介

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教育背景

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工作经历

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荣誉奖项

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Simultaneous LC–MS/MS method for the quantification of 5-flucytosine, ganciclovir, and valganciclovir to support combined prodrug-activated gene therapy

同时LC–MS/MS方法用于5-flucytosine、ganciclovir和valganciclovir的定量，以支持联合前药激活的基因治疗

Journal of Chromatography B

IF0

2026-04-060

PRE

Development of selumetinib–loaded solid dispersion based on low molecular weight methylcellulose for the enhanced solubility, stability, dissolution, and bioavailability

基于低分子量甲基纤维素负载塞来替尼的固体分散体的开发，以提高溶解度、稳定性、溶出度和生物利用度

International Journal of Biological Macromolecules

IF8.5

2025-12-080

PRE

Pyrazole-Based Transthyretin Kinetic Stabilizers Identified Using a Covalent Fluorescent Probe Assay for Selectivity Profiling in Human Serum

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-12-010

PRE

Artificial intelligence-based quantitative analysis of hepatic fibrosis in carbon tetrachloride-induced mouse model of metabolic dysfunction-associated steatohepatitis

基于人工智能的代谢功能障碍相关脂肪性肝炎四氯化碳诱导小鼠模型中肝纤维化的定量分析

TOXICOLOGICAL RESEARCH

IF2.3

2025-11-010

Preclinical Pharmacokinetics of DM5167, a Novel Selective PARP1 Inhibitor

DM5167的预临床药代动力学研究，DM5167是一种新型选择性PARP1抑制剂

Pharmaceutical Research

IF4.3

2025-10-220

PRE

Development of Gastroretentive Floating Combination Tablets Containing Amoxicillin Trihydrate 500 mg and Levofloxacin 125 mg for Eradicating Resistant Helicobacter pylori

PHARMACEUTICS

IF5.5

2024-09-241

OAAI

Stability Evaluation and Pharmacokinetic Profiling of Vepdegestrant in Rodents Using Liquid Chromatography-Tandem Mass Spectrometry

MOLECULES

IF4.6

2024-08-272

OAAI

Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson's Disease Candidate, Using LC-MS/MS and LC-HRMS

使用lc-ms/MS和lc-hrms对帕金森氏病候选KM-819的大鼠药代动力学和体外代谢物鉴定

MOLECULES

IF4.6

2024-02-251

OAAI

DM5167, a novel selective PARP1 inhibitor, efficiently reduces growth of triple-negative breast cancers

CANCER RESEARCH

IF16.6

2023-04-040

PRE

The Development of Super-Saturated Rebamipide Eye Drops for Enhanced Solubility, Stability, Patient Compliance, and Bioavailability

开发超饱和瑞巴派特滴眼液，以提高溶解度，稳定性，患者依从性和生物利用度

PHARMACEUTICS

IF5.5

2023-03-153

OAAI

Novel Strategy To Inhibit Transthyretin Amyloidosis via the Synergetic Effect of Chemoselective Acylation and Noncovalent Inhibitor Release

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-02-073

PRE

Design and Synthesis of a Novel 4-aryl-N-(2-alkoxythieno [2,3-b]pyrazine-3-yl)-4-arylpiperazine-1-carboxamide DGG200064 Showed Therapeutic Effect on Colon Cancer through G2/M Arrest

PHARMACEUTICALS

IF4.8

2022-04-205

OAAI

Development of an LC-MS/MS Method for ARV-110, a PROTAC Molecule, and Applications to Pharmacokinetic Studies

MOLECULES

IF4.6

2022-03-1840

OAAI

Synthesis and biological evaluation of quinolone derivatives as transthyretin amyloidogenesis inhibitors and fluorescence sensors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2022-01-017

PRE

Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats

PHARMACEUTICS

IF5.5

2021-03-113

OAAI

The Development and Optimization of Hot-Melt Extruded Amorphous Solid Dispersions Containing Rivaroxaban in Combination with Polymers

PHARMACEUTICS

IF5.5

2021-03-0615

OAAI

ERRγ ligand HPB2 upregulates BDNF-TrkB and enhances dopaminergic neuronal phenotype

Err γ 配体HPB2上调bdnf-trkb并增强多巴胺能神经元表型

PHARMACOLOGICAL RESEARCH

IF10.5

2021-03-0121

PREAI

Protective effects of PARP1-inhibitory compound in dry age-related macular degeneration

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2021-01-017

OAAI

Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy

齐墩果酸聚合物胶束的研制及其临床疗效评价

NANOSCALE RESEARCH LETTERS

IF4.1

2020-06-2220

OAAI

Determination of motolimod concentration in rat plasma by liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2020-02-016

PREAI

Tae-Sung Koo

个人简介

教育背景

工作经历

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