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M

Michela Ranieri

Laura and Isaac Perlmutter Cancer Center
H指数:19
被引数:1,256

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Deep mutational scanning reveals EGFR mutations conferring resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945

深度突变扫描揭示了赋予对第四代EGFR酪氨酸激酶抑制剂BLU-945耐药性的EGFR突变。

npj Precision Oncology
IF8
2025-08-200
OAAI
Yueyang Wang; Yuan Hao; Michela Ranieri; Tigran M. Abramyan; Lev Tsidilkovski; Michelle Hollenberg; Alfonso Lopez; Xavier T. R. Moore; Fiona Sherman; Jiehui Deng; Hayk Saribekyan; Garegin Papoian; Kwok-Kin Wong; Elaine Shum; John T. Poirier
BBO-8520, a first-in-class, direct inhibitor of KRASG12C (ON), locks GTP-bound KRASG12C in the state 1 conformation resulting in rapid and complete blockade of effector binding
CANCER RESEARCH
IF16.6
2024-04-052
PRE
Maciag, Anna E.; Stice, James; Wang, Bin; Sharma, Alok; Chan, Albert; Lin, Ken; Singh, Devansh; Dyba, Marcin; Yang, Yue; Setoodeh, Saman; Smith, Brian P.; Rabara, Dana; Zhang, Zuhui; Larsen, Erik K.; Esposito, Dom; Denson, John Paul; Ranieri, Michela; Meynardie, Mary; Mehdizadeh, Sadaf; Alexander, Patrick; Blanco, Maria Abreu; Turner, David; Xu, Rui; Lightstone, Felice C.; Wong, Kwok Kin; Simanshu, Dhirendra; Wang, Keshi; Stephen, Andrew G.; Sinkevicius, Kerstin; Nissley, Dwight V.; Wallace, Eli; McCormick, Frank; Beltran, Pedro J.
FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-01-169
OAAI
Okato, Atsushi; Utsumi, Takanobu; Ranieri, Michela; Zheng, Xingnan; Zhou, Mi; Pereira, Luiza D.; Chen, Ting; Kita, Yuki; Wu, Di; Hyun, Hyesun; Lee, Hyojin; Gdowski, Andrew S.; Raupp, John D.; Clark-Garvey, Sean; Manocha, Ujjawal; Chafitz, Alison; Sherman, Fiona; Stephens, Janaye; Rose, Tracy L.; Milowsky, Matthew I.; Wobker, Sara E.; Serody, Jonathan S.; Damrauer, Jeffrey S.; Wong, Kwok-Kin; Kim, William Y.
Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy
CANCER RESEARCH
IF16.6
2023-09-2030
OA
Mukhopadhyay, Suman; Huang, Hsin-Yi; Lin, Ziyan; Ranieri, Michela; Li, Shuai; Sahu, Soumyadip; Liu, Yingzhuo; Ban, Yi; Guidry, Kayla; Hu, Hai; Lopez, Alfonso; Sherman, Fiona; Tan, Yi Jer; Lee, Yeuan Ting; Armstrong, Amanda P.; Dolgalev, Igor; Sahu, Priyanka; Zhang, Tinghu; Lu, Wenchao; Gray, Nathanael S.; Christensen, James G.; Tang, Tracy T.; Velcheti, Vamsidhar; Khodadadi-Jamayran, Alireza; Wong, Kwok-Kin; Neel, Benjamin G.
Clinical, neurophysiological and neuroradiological characteristics of 30 cases of SARS-COV-2-associated encephalitis in Lombardia
JOURNAL OF THE NEUROLOGICAL SCIENCES
IF3.2
2021-10-010
OAAI
Boneschi, Filippo Martinelli; Sessa, Maria; Guidetti, Donata; Grampa, Giampiero; Magni, Eugenio; Versino, Maurizio; Ferrarese, Carlo; Zarcone, Davide; Prelle, Alessandro; Micieli, Giuseppe; Zanferrari, Carla; Frediani, Fabio; Cagnana, Antonio; Zilioli, Angelo; Calloni, Maria; Mariani, Emilio; Foresti, Camillo; Crabbio, Massimo; La Spina, Isidoro; Dal Maschio, Vera Pacoova; Giorgettii, Andrea; Cavallini, Anna; Ranieri, Michela; D'Adda, Elisabetta; Salmaggi, Andrea; Colombo, Antonio
Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non-Small Cell Lung Cancer
CANCER RESEARCH
IF16.6
2020-09-0218
OAAI
Li, Fei; Ng, Wai-Lung; Luster, Troy A.; Hu, Hai; Sviderskiy, Vladislav O.; Dowling, Catriona M.; Hollinshead, Kate E. R.; Zouitine, Paula; Zhang, Hua; Huang, Qingyuan; Ranieri, Michela; Wang, Wei; Fang, Zhaoyuan; Chen, Ting; Deng, Jiehui; Zhao, Kai; So, Hon-Cheong; Khodadadi-Jamayran, Alireza; Xu, Mousheng; Karatza, Angeliki; Pyon, Val; Li, Shuai; Pan, Yuanwang; Labbe, Kristen; Almonte, Christina; Poirier, John T.; Miller, George; Possemato, Richard; Qi, Jun; Wong, Kwok-Kin
In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma

体内表观遗传CRISPR筛选将Asf1a鉴定为Kras突变肺腺癌的免疫治疗靶点

CANCER DISCOVERY
IF33.3
2020-02-05149
OAAI
Li, Fei; Huang, Qingyuan; Luster, Troy A.; Hu, Hai; Zhang, Hua; Ng, Wai-Lung; Khodadadi-Jamayran, Alireza; Wang, Wei; Chen, Ting; Deng, Jiehui; Ranieri, Michela; Fang, Zhaoyuan; Pyon, Val; Dowling, Catriona M.; Bagdatlioglu, Ece; Almonte, Christina; Labbe, Kristen; Silver, Heather; Rabin, Alexandra R.; Jani, Kandarp; Tsirigos, Aristotelis; Papagiannakopoulos, Thales; Hammerman, Peter S.; Velcheti, Vamsidhar; Freeman, Gordon J.; Qi, Jun; Miller, George; Wong, Kwok-Kin

研究方向

暂未获取到该数据
K
Kwok‐Kin Wong
H 指数:140论文数:1,660被引数:7.3万
A
Antonio Di Cristofano
H 指数:39论文数:184被引数:1.1万
J
Jiehui Deng
H 指数:31论文数:298被引数:6,325
E
Eugenio Parati
H 指数:58论文数:320被引数:1.6万
A
Alireza Khodadadi‐Jamayran
H 指数:34论文数:296被引数:3,705
D
Daniela De Martino
H 指数:15论文数:44被引数:927
F
Fiona Sherman
H 指数:7论文数:67被引数:358
H
Hai Hu
H 指数:17论文数:83被引数:2,670
A
Anna Bersano
H 指数:48论文数:312被引数:8,038
C
Cinzia Del Giovane
H 指数:51论文数:254被引数:1.4万