Björn Oskarsson - Publications, H-index & Citations

Björn Oskarsson

mayo clinic

37H指数

163论文数

5.2K被引数

收录论文 48

发表时间

N-of-1 investigational study of a novel antisense oligonucleotide drug in CHCHD10-related ALS shows early signs of efficacy N-of-1研究显示，一种新型反义寡核苷酸药物在CHCHD10相关ALS中表现出早期疗效

Med

IF11.8

2026-09-14

PREAI

Margot A. Cousin; Aditi I. Dagli; Laurence Mignon; Jaimin S. Shah; Mercedes Prudencio; Tania F. Gendron; Angita Jain; Evan Udine; Marka van Blitterswijk; Erik H. Middlebrooks; Megan H. Donahue; Jany E. Dagher; Jens O. Watzlawik; Wolfdieter Springer; Tejal Parekh; Zachary T. McEachin; Leonard Petrucelli; Björn Oskarsson

Expanding the Motor Band Sign in Motor Neuron Disease Using 7T MRI: Visualization of Cortical Layer-Dependent Iron Deposition in the Primary Motor Cortex 利用7T MRI扩展运动神经元病中的运动频带征：可视化初级运动皮层中铁沉积的皮层分层依赖性

Muscle & Nerve

IF3.1

2026-03-06

PREAI

Jaimin S. Shah; Björn Oskarsson; Xiangzhi Zhou; Michael G. Heckman; Hanna J. Sledge; Gabriel Virador; Donna Parizadeh; Erik H. Middlebrooks

Prospective Validation of the New PLS Diagnostic Criteria From PLS Natural History Study: EMG and Neurofilament Analyses 基于PLS自然病史研究的EMG和神经丝蛋白分析对新PLS诊断标准的预期验证

Muscle & Nerve

IF3.1

2026-03-02

PREAI

Eric Sorenson; Daragh Heitzman; Ikjae Lee; Grace Jang; Lauren Elman; Ali A. Habib; James Wymer; Ghazala Hayat; Stephen A. Goutman; J. Americo M. Fernandes; Mary Kay Floeter; Senda Ajroud-Driss; Kelly Gwathmey; Edward Kasarskis; Yasushi Y. Kisanuki; Catherine Lomen-Hoerth; David Walk; Wendy S. Johnston; Frank Diaz; Nicholas J. Maragakis; Sabrina Paganoni; Jaimin Shah; Bjorn Oskarsson; Lorne Zinman; Terry Heiman-Patterson; Omar Jawdat; Christina N. Fournier; Michael T. Pulley; Stephen N. Scelsa; Christen Shoesmith; Zachary Simmons; Alexander V. Sherman; Benjamin N. Hoover; Rebecca Y. Yun; Ken Cheung; Hiroshi Mitsumoto; for the PLS NHS Study Group

Quantitative Measures of Time to Loss of 15% Vital Capacity and Survival Extension in Slowly Progressive Amyotrophic Lateral Sclerosis (ALS) Patients Treated with the Immune Regulator NP001 Suggests an Immunopathogenic Subset of ALS 以免疫调节剂NP001治疗缓慢进展型肌萎缩侧索硬化症(ALS)患者时，对15%肺活量丧失时间和生存期延长的定量测量表明存在一种免疫病理亚型ALS。

Biomedicines 2025, Vol. 13, Page 3060

IF3.9

2025-12-12

OAAI

Namita A. Goyal; Jinsy A. Andrews; Björn E. Oskarsson; Martina H. Wiedau; Edward J. Kasarskis; Bruce D. Forrest; Rongzhen Zhang; Paige M. Bracci; Matthew W. Davis; Ari Azhir; Michael S. McGrath

Expanding the spectrum of annexin A11 proteinopathy in frontotemporal lobar degeneration and motor neuron disease 扩展前颞叶萎缩和运动神经元病中annexin A11蛋白病的谱系

Acta Neuropathologica

IF9.3

2025-11-12

OAAI

Nikhil B. Ghayal; Richard J. Crook; Angita Jain; Gunveen Sachdeva; Peizhou Jiang; Shanu F. Roemer; Hiroaki Sekiya; Michael A. DeTure; Matthew C. Baker; Wouter De Coster; Björn Oskarsson; Keith A. Josephs; Rosa Rademakers; Marka M. van Blitterswijk; Dennis W. Dickson

Rod-shaped microglia interact with neuronal dendrites to attenuate cortical excitability during TDP-43-related neurodegeneration 杆状小胶质细胞与神经元树突相互作用，以降低皮质兴奋性，从而缓解TDP-43相关神经退行性变。

Immunity

IF26.3

2025-09-19

PREAI

Manling Xie; Yue Liang; Alessandra S. Miller; Praveen N. Pallegar; Anthony D. Umpierre; Na Wang; Shuwen Zhang; Nagaswaroop Kengunte Nagaraj; Zachary C. Fogarty; Nikhil B. Ghayal; Björn Oskarsson; Shunyi Zhao; Jiaying Zheng; Wu Shi; Mastura Akter; Fangfang Qi; Aivi T. Nguyen; Dennis W. Dickson; Long-Jun Wu

Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment 原发性侧索硬化自然史研究：原发性侧索硬化功能评分量表及其他结局评估

ANNALS OF NEUROLOGY

IF7.7

2025-09-01

PREAI

Lee, Ikjae; Jang, Grace; Cheung, Ying Kuen (Ken); Sherman, Alexander V.; Johnston, Wendy S.; Diaz, Frank; Fernandes, J. Americo M.; Habib, Ali A.; Maragakis, Nicholas J.; Paganoni, Sabrina; Burke, Katherine; Oskarsson, Bjorn; Shah, Jaimin; Zinman, Lorne; Floeter, Mary Kay; Ajroud-Driss, Senda; Gwathmey, Kelly; Heiman-Patterson, Terry; Jawdat, Omar; Kasarskis, Edward J.; Kisanuki, Yaz Y.; Wymer, James; Fournier, Christina; Hayat, Ghazala; Heitzman, Daragh; Lomen-Hoerth, Catherine; Pulley, Michael T.; Scelsa, Stephen N.; Walk, David; Goutman, Stephen A.; Shoesmith, Christen; Simmons, Zachary; Sorenson, Eric; Elman, Lauren; Harms, Matthew B.; Hoover, Benjamin N.; Yun, Rebecca Y.; Santella, Regina M.; Mitsumoto, Hiroshi; PLS NHS Study Grp

Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes FTLD患者TDP-43病理的表观基因组分析鉴定出与病理亚型相关的特异表观遗传特征

Molecular Neurodegeneration

IF17.5

2025-08-26

PREAI

Cristina T. Vicente; Tejasvi Niranjan; Elise Coopman; Júlia Faura; Sara Alidadiani; Claudia Schrauwen; Billie J. Matchett; Bavo Heeman; Marleen Van den Broeck; Wouter De Coster; Thuy Nguyen; Julie S. Lau; Saurabh Baheti; Tim de Pooter; Peter De Rijk; Mojca Strazisar; Matt Baker; Mariely DeJesus-Hernandez; NiCole A. Finch; Cyril Pottier; Marka van Blitterswijk; Yan Asmann; Melissa E. Murray; Leonard Petrucelli; Andrew King; Claire Troakes; Safa Al-Sarraj; Robert A. Rissman; Annie Hiniker; Margaret Flanagan; Bret M. Evers; Charles L. White; Carlos Cruchaga; Rudolph Castellani; Jeroen G.J. van Rooij; Merel O. Mol; Harro Seelaar; John C. van Swieten; Björn Oskarsson; Robert Ross Reichard; Aivi T. Nguyen; Keith A. Josephs; Ronald C. Petersen; Nilüfer Ertekin-Taner; Bradley F. Boeve; Neill R. Graff-Radford; Sarah Weckhuysen; Dennis W. Dickson; Rosa Rademakers

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS C9orf72相关ALS中反义寡核苷酸疗法的分子影响

Cell

IF42.5

2025-08-26

OAAI

Zachary T. McEachin; Mingee Chung; Sabrina A. Stratton; Changhee Han; Woo Jae Kim; Udit Sheth; Eleanor V. Thomas; Ethan Issenberg; Tanvi Kamra; Paola Merino; Yona Levites; Nisha Raj; Eric B. Dammer; Duc M. Duong; Lingyan Ping; Anantharaman Shantaraman; Adam N. Trautwig; Joshna Gadhavi; Ezana Assefa; Marla Gearing; Kaylor M. Kelly; Shanu F. Roemer; Michael DeTure; Seneshaw Asress; Thomas Kukar; Christina Fournier; Dennis W. Dickson; Leonard Petrucelli; Todd E. Golde; Björn Oskarsson; Tania F. Gendron; Nicholas T. Seyfried; Jonathan D. Glass

Placebo-Controlled, Randomized Double-Blind N-Of-1 Trial to Study Safety and Potential Efficacy of TJ-68 for Improving Muscle Cramps in Patients With Amyotrophic Lateral Sclerosis: A Pilot Study 安慰剂对照、随机双盲N-of-1试验研究TJ-68在改善肌萎缩侧索硬化症患者肌肉痉挛中的安全性与潜在疗效：一项试点研究

Muscle & Nerve

IF3.1

2025-06-23

OAAI

Hiroshi Mitsumoto; Ken Cheung; Björn Oskarsson; Grace E. Jang; Howard F. Andrews; Stephen Johnson; Jaimin S. Shah; Joseph Americo Fernandes Jr; Jinsy A. Andrews; Maya Rao; Martin McElhiney

Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing FTLD-TDP前额皮质剪接景观的分析揭示了亚型特异模式及隐匿剪接。

Acta Neuropathologica

IF9.3

2025-06-06

OAAI

Júlia Faura; Bavo Heeman; Cyril Pottier; Matthew C. Baker; Mariely DeJesus-Hernandez; Fahri Küçükali; Laura Heiß; Sarah Wynants; Marleen Van den Broeck; Peter De Rijk; Tim De Pooter; Geert Joris; NiCole A. Finch; Yan Asmann; Mojca Strazisar; Melissa E. Murray; Leonard Petrucelli; Björn Oskarsson; Kristel Sleegers; Keith A. Josephs; Aivi T. Nguyen; R. Ross Reichard; Ronald C. Petersen; Bradley F. Boeve; Neill R. Graff-Radford; Dennis W. Dickson; Marka van Blitterswijk; Rosa Rademakers

Targeted long-read sequencing to quantify methylation of the C9orf72 repeat expansion

MOLECULAR NEURODEGENERATION

IF17.5

2024-12-21

OAAI

Udine, Evan; Finch, NiCole A.; DeJesus-Hernandez, Mariely; Jackson, Jazmyne L.; Baker, Matthew C.; Saravanaperumal, Siva Arumugam; Wieben, Eric; Ebbert, Mark T. W.; Shah, Jaimin; Petrucelli, Leonard; Rademakers, Rosa; Oskarsson, Bjorn; van Blitterswijk, Marka

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (vol 19, 29, 2024)

MOLECULAR NEURODEGENERATION

IF17.5

2024-07-27

OAAI

Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; DeTure, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjorn; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard

Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion

ACTA NEUROPATHOLOGICA

IF9.3

2024-04-19

OAAI

Udine, Evan; DeJesus-Hernandez, Mariely; Tian, Shulan; das Neves, Sofia Pereira; Crook, Richard; Finch, NiCole A.; Baker, Matthew C.; Pottier, Cyril; Graff-Radford, Neill R.; Boeve, Bradley F.; Petersen, Ronald C.; Knopman, David S.; Josephs, Keith A.; Oskarsson, Bjorn; Da Mesquita, Sandro; Petrucelli, Leonard; Gendron, Tania F.; Dickson, Dennis W.; Rademakers, Rosa; van Blitterswijk, Marka

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases

MOLECULAR NEURODEGENERATION

IF17.5

2024-03-27

OAAI

Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; Deture, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjoern; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD 错误剪接的转录本在TDP-43-related ALS/FTD中产生新生蛋白

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-02-14

OAAI

Seddighi, Sahba; Qi, Yue A.; Brown, Anna-Leigh; Wilkins, Oscar G.; Bereda, Colleen; Belair, Cedric; Zhang, Yong-Jie; Prudencio, Mercedes; Keuss, Matthew J.; Khandeshi, Aditya; Pickles, Sarah; Kargbo-Hill, Sarah E.; Hawrot, James; Ramos, Daniel M.; Yuan, Hebao; Roberts, Jessica; Sacramento, Erika Kelmer; Shah, Syed I.; Nalls, Mike A.; Colon-Mercado, Jennifer M.; Reyes, Joel F.; Ryan, Veronica H.; Nelson, Matthew P.; Cook, Casey N.; Li, Ziyi; Screven, Laurel; Kwan, Justin Y.; Mehta, Puja R.; Zanovello, Matteo; Hallegger, Martina; Shantaraman, Anantharaman; Ping, Lingyan; Koike, Yuka; Oskarsson, Bjorn; Staff, Nathan P.; Duong, Duc M.; Ahmed, Aisha; Secrier, Maria; Ule, Jernej; Jacobson, Steven; Reich, Daniel S.; Rohrer, Jonathan D.; Malaspina, Andrea; Dickson, Dennis W.; Glass, Jonathan D.; Ori, Alessandro; Seyfried, Nicholas T.; Maragkakis, Manolis; Petrucelli, Leonard; Fratta, Pietro; Ward, Michael E.

TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-01-17

OAAI

Marks, Jordan D.; Ayuso, Virginia Estades; Carlomagno, Yari; Yue, Mei; Todd, Tiffany W.; Hao, Ying; Li, Ziyi; McEachin, Zachary T.; Shantaraman, Anantharaman; Duong, Duc M.; Daughrity, Lillian M.; Jansen-West, Karen; Shao, Wei; Calliari, Anna; Bejarano, Jesus Gonzalez; DeTure, Michael; Rawlinson, Bailey; Casey, Monica Castanedes; Lilley, Meredith T.; Donahue, Megan H.; Jawahar, Vidhya Maheswari; Boeve, Bradley F.; Petersen, Ronald C.; Knopman, David S.; Oskarsson, Bjoern; Graff-Radford, Neill R.; Wszolek, Zbigniew K.; Dickson, Dennis W.; Josephs, Keith A.; Qi, Yue A.; Seyfried, Nicholas T.; Ward, Michael E.; Zhang, Yong-Jie; Prudencio, Mercedes; Petrucelli, Leonard; Cook, Casey N.

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

CELL REPORTS

IF6.9

2023-08-01

OAAI

Park, Jinyoung; Wu, Yanwei; Shao, Wei; Gendron, Tania F.; van der Spek, Sophie J. F.; Sultanakhmetov, Grigorii; Basu, Avik; Otero, Paula Castellanos; Jones, Caroline J.; Jansen-West, Karen; Daughrity, Lillian M.; Phanse, Sadhna; del Rosso, Giulia; Tong, Jimei; Castanedes-Casey, Monica; Jiang, Lulu; Libera, Jenna; Oskarsson, Bjorn; Dickson, Dennis W.; Sanders, David W.; Brangwynne, Clifford P.; Emili, Andrew; Wolozin, Benjamin; Petrucelli, Leonard; Zhang, Yong-Jie

Multisystem Proteinopathies (MSP) and MSP-like Disorders: Clinical-Pathological-Molecular Spectrum and Long-term Follow Up

NEUROLOGY

IF8.5

2023-04-25

PREAI

Chompoopong, Pitcha; Oskarsson, Bjorn; Madigan, Nicolas; Mirman, Igal; Martinez-Thompson, Jennifer; Liewluck, Teerin; Milone, Margherita

Results from the first four regimens of the HEALEY ALS Platform Trial

NEUROLOGY

IF8.5

2023-04-25

PREAI

Paganoni, Sabrina; Berry, James; Quintana, Melanie; Macklin, Eric; Saville, Benjamin; Andrews, Jinsy; Shefner, Jeremy; Fournier, Christina; Babu, Suma; Maragakis, Nicholas; Oskarsson, Bjorn; Detry, Michelle; Chase, Marianne; Sherman, Alex; Yu, Hong; Pothier, Lindsay; Drake, Kristin; Chibnik, Lori; Bind, Marie-Abele; Vestrucci, Matteo; McGlothlin, Anna; Marion, Joseph; Duda, Petra; Harvey, Brittany; Qureshi, Irfan; Donohue, Mary; Granit, Volkan; Grossman, Katheryn; Glanzman, Robert; Hotchkin, Michael; Goldberg, Y. Paul; Leitner, Melanie; Hayden, Michael; Cudkowicz, Merit

研究方向