Tania F. Gendron - Publications, H-index & Citations

Tania F. Gendron

mayo clinic

68H指数

189论文数

1.7W被引数

收录论文 107

发表时间

N-of-1 investigational study of a novel antisense oligonucleotide drug in CHCHD10-related ALS shows early signs of efficacy N-of-1研究显示，一种新型反义寡核苷酸药物在CHCHD10相关ALS中表现出早期疗效

Med

IF11.8

2026-09-14

PREAI

Margot A. Cousin; Aditi I. Dagli; Laurence Mignon; Jaimin S. Shah; Mercedes Prudencio; Tania F. Gendron; Angita Jain; Evan Udine; Marka van Blitterswijk; Erik H. Middlebrooks; Megan H. Donahue; Jany E. Dagher; Jens O. Watzlawik; Wolfdieter Springer; Tejal Parekh; Zachary T. McEachin; Leonard Petrucelli; Björn Oskarsson

Longitudinal Dynamics of Polyglutamine-Expanded ATXN3 in Biofluids of Spinocerebellar Ataxia Type 3 脊髓小脑共济失调3型生物液体中Polyglutamine扩展的ATXN3的纵向动力学

Movement Disorders

IF7.6

2026-07-29

PREAI

Jordan Bartfield BS; Lukasz Milanowski MD, PhD; Karen R. Jansen-West BS; Rana Hanna Al-Shaikh MD; Tomasz Chmiela MD, PhD; Tania F. Gendron PhD; Judith A. Dunmore BS

Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays 测量人血浆和脑脊液中的神经丝轻链：五种分析免疫测定法的比较

CLINICAL CHEMISTRY AND LABORATORY MEDICINE

IF3.7

2025-09-01

PREAI

Sheth, Udit; Harrison, Rebecca; Ferber, Kyle; Rosenbaugh, Erin G.; Bevis, Amanda; Khillan, Rohini; Benatar, Michael; Bjorklund, Nicole L.; Di Daniel, Elena; Harris, Glenn A.; Kahn, Olga I.; Liu, Yongge; Zetterberg, Henrik; Mitic, Laura L.; Graham, Danielle; Gendron, Tania F.

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC-Derived Microglia and Modulates Glial-Neuronal Crosstalk C9orf72重复扩展在人类iPSC源性小胶质细胞中诱导代谢功能障碍并调节胶质细胞-神经元相互作用

Glia

IF5.1

2025-09-01

OAAI

Marika Mearelli; Insa Hirschberg; Christin Weissleder; Carmela Giachino; María José Pérez; Malvina Dubroux; Francesca Provenzano; Mafalda Rizzuti; Linda Ottoboni; Udit Sheth; Tania F. Gendron; Stefania Corti; Michela Deleidi

Endolysosomal dysfunction impairs proteostasis and induces neurodegeneration in vivo 内体-溶酶体功能障碍损害蛋白质稳态并诱导体内神经退行性变

iScience

IF4.1

2025-08-27

OAAI

Wei Shao; Ellen A. Albagli; Karen Jansen-West; Lillian M. Daughrity; Jimei Tong; Anxhela Hysi; Peizhou Jiang; Tiffany W. Todd; Emma Lee; Desiree Zanetti Alepuz; Yari Carlomagno; Mei Yue; Judith A. Dunmore; Monica Castanedes-Casey; Paula Castellanos Otero; Aishe Kurti; Mercedes Prudencio; Casey N. Cook; Dennis W. Dickson; Tania F. Gendron; Leonard Petrucelli; Yong-Jie Zhang

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS C9orf72相关ALS中反义寡核苷酸疗法的分子影响

Cell

IF42.5

2025-08-26

OAAI

Zachary T. McEachin; Mingee Chung; Sabrina A. Stratton; Changhee Han; Woo Jae Kim; Udit Sheth; Eleanor V. Thomas; Ethan Issenberg; Tanvi Kamra; Paola Merino; Yona Levites; Nisha Raj; Eric B. Dammer; Duc M. Duong; Lingyan Ping; Anantharaman Shantaraman; Adam N. Trautwig; Joshna Gadhavi; Ezana Assefa; Marla Gearing; Kaylor M. Kelly; Shanu F. Roemer; Michael DeTure; Seneshaw Asress; Thomas Kukar; Christina Fournier; Dennis W. Dickson; Leonard Petrucelli; Todd E. Golde; Björn Oskarsson; Tania F. Gendron; Nicholas T. Seyfried; Jonathan D. Glass

Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD 异常剪接使C9orf72重复扩展在ALS/FTD中发生外显子化

Nature Neuroscience

IF20

2025-08-11

OAAI

Suzhou Yang; Denethi Wijegunawardana; Udit Sheth; Austin M. Veire; Juliana M. S. Salgado; Tanina Arab; Manasi Agrawal; Jeffrey Zhou; João D. Pereira; Tania F. Gendron; Junjie U. Guo

Author Correction: Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration 作者更正: 脑脊液蛋白质组的大规模网络分析确定了额颞叶变性的分子特征

Nature Aging

IF19.4

2025-07-07

OAAI

Rowan Saloner; Adam M. Staffaroni; Eric B. Dammer; Erik C. B. Johnson; Emily W. Paolillo; Amy Wise; Hilary W. Heuer; Leah K. Forsberg; Argentina Lario-Lago; Julia D. Webb; Jacob W. Vogel; Alexander F. Santillo; Oskar Hansson; Joel H. Kramer; Bruce L. Miller; Jingyao Li; Joseph Loureiro; Rajeev Sivasankaran; Kathleen A. Worringer; Nicholas T. Seyfried; Jennifer S. Yokoyama; Salvatore Spina; Lea T. Grinberg; William W. Seeley; Lawren VandeVrede; Peter A. Ljubenkov; Ece Bayram; Andrea Bozoki; Danielle Brushaber; Ciaran M. Considine; Gregory S. Day; Bradford C. Dickerson; Kimiko Domoto-Reilly; Kelley Faber; Douglas R. Galasko; Tania Gendron; Daniel H. Geschwind; Nupur Ghoshal; Neill Graff-Radford; Chadwick M. Hales; Lawrence S. Honig; Ging-Yuek R. Hsiung; Edward D. Huey; John Kornak; Walter Kremers; Maria I. Lapid; Suzee E. Lee; Irene Litvan; Corey T. McMillan; Mario F. Mendez; Toji Miyagawa; Alexander Pantelyat; Belen Pascual; Joseph Masdeu; Henry L. Paulson; Leonard Petrucelli; Peter Pressman; Rosa Rademakers; Eliana Marisa Ramos; Katya Rascovsky; Erik D. Roberson; Rodolfo Savica; Allison Snyder; Anna Campbell Sullivan; M. Carmela Tartaglia; Marijne Vandebergh; Brad F. Boeve; Howie J. Rosen; Julio C. Rojas; Adam L. Boxer; Kaitlin B. Casaletto

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders 全面的血浆胶质纤维酸性蛋白和神经丝蛋白轻链在额颞叶痴呆谱系障碍中的横断面和纵向比较

MOLECULAR NEURODEGENERATION

IF17.5

2025-03-12

OAAI

Sheth, Udit; Oijerstedt, Linn; Heckman, Michael G.; White, Launia J.; Heuer, Hilary W.; Lario Lago, Argentina; Forsberg, Leah K.; Faber, Kelley M.; Foroud, Tatiana M.; Rademakers, Rosa; Ramos, Eliana Marisa; Appleby, Brian S.; Bozoki, Andrea C.; Darby, R. Ryan; Dickerson, Bradford C.; Domoto-Reilly, Kimiko; Galasko, Douglas R.; Ghoshal, Nupur; Graff-Radford, Neill R.; Grant, Ian M.; Hales, Chadwick M.; Hsiung, Ging-Yuek Robin; Huey, Edward D.; Irwin, David; Kwan, Justin Y.; Litvan, Irene; Mackenzie, Ian R.; Masdeu, Joseph C.; Mendez, Mario F.; Onyike, Chiadi U.; Pascual, Belen; Pressman, Peter S.; Roberson, Erik D.; Snyder, Allison; Tartaglia, M. Carmela; Seeley, William W.; Dickson, Dennis W.; Rosen, Howard J.; Boeve, Bradley F.; Boxer, Adam L.; Petrucelli, Leonard; Gendron, Tania F.

pTDP-43 levels correlate with cell type-specific molecular alterations in the prefrontal cortex of C9orf72 ALS/FTD patients pTDP-43水平与C9orf72 ALS/FTD患者前额叶皮层中细胞类型特异性的分子改变相关联。

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-02-25

OAAI

Wang, Hsiao-Lin V.; Xiang, Jian - Feng; Yuan, Chenyang; Veire, Austin M.; Gendron, Tania F.; Murray, Melissa E.; Tarse, Malu G.; Hu, Jian; Gearing, Marla; Glass, Jonathan D.; Jin, Peng; Corces, Victor G.; Mceachin, Zachary T.

HDGFL2 cryptic protein: a portal to detection and diagnosis in neurodegenerative disease

MOLECULAR NEURODEGENERATION

IF17.5

2024-10-25

OAAI

Albagli, Ellen A.; Calliari, Anna; Gendron, Tania F.; Zhang, Yong-Jie

Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration

NEUROLOGY

IF8.5

2024-10-22

PREAI

Vandebergh, Marijne; Ramos, Eliana Marisa; Corriveau-Lecavalier, Nick; Ramanan, Vijay K.; Kornak, John; Mester, Carly; Kolander, Tyler; Brushaber, Danielle E.; Staffaroni, Adam M.; Geschwind, Daniel H.; Wolf, Amy A.; Kantarci, Kejal; Gendron, Tania; Petrucelli, Leonard; van den Broeck, Marleen; Wynants, Sarah; Baker, Matthew; Borrego-ecija, Sergi; Appleby, Brian; Barmada, Sami; Bozoki, Andrea C.; Clark, David; Darby, R. Ryan; Dickerson, Bradford C.; Domoto-Reilly, Kimiko; Fields, Julie A.; Galasko, Douglas; Ghoshal, Nupur; Graff-Radford, Neill R.; Grant, Ian M.; Honig, Lawrence S.; Hsiung, Ging-Yuek R.; Huey, Edward D.; Irwin, David J.; Knopman, David S.; Kwan, Justin Y.; Leger, Gabriel C.; Litvan, Irene; Masdeu, Joseph C.; Mendez, Mario F.; Onyike, Chiadi U.; Pascual, Belen; Pressman, Peter S.; Ritter, Aaron; Roberson, Erik D.; Snyder, Allison; Sullivan, Anna Campbell; Tartaglia, Maria Carmela; Wint, Dylan; Heuer, Hilary W.; Forsberg, Leah K.; Boxer, Adam L.; Rosen, Howard J.; Boeve, Bradley F.; Rademakers, Rosa

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (vol 19, 29, 2024)

MOLECULAR NEURODEGENERATION

IF17.5

2024-07-27

OAAI

Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; DeTure, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjorn; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard

Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion

ACTA NEUROPATHOLOGICA

IF9.3

2024-04-19

OAAI

Udine, Evan; DeJesus-Hernandez, Mariely; Tian, Shulan; das Neves, Sofia Pereira; Crook, Richard; Finch, NiCole A.; Baker, Matthew C.; Pottier, Cyril; Graff-Radford, Neill R.; Boeve, Bradley F.; Petersen, Ronald C.; Knopman, David S.; Josephs, Keith A.; Oskarsson, Bjorn; Da Mesquita, Sandro; Petrucelli, Leonard; Gendron, Tania F.; Dickson, Dennis W.; Rademakers, Rosa; van Blitterswijk, Marka

Apilimod dimesylate in C9orf72 amyotrophic lateral sclerosis: a randomized phase 2a clinical trial

BRAIN

IF11.7

2024-04-12

PREAI

Babu, Suma; Nicholson, Katharine A.; Rothstein, Jeffrey D.; Swenson, Andrea; Sampognaro, Paul J.; Pant, Pravin; Macklin, Eric A.; Spruill, Susan; Paganoni, Sabrina; Gendron, Tania F.; Prudencio, Mercedes; Petrucelli, Leonard; Nix, Darrell; Landrette, Sean; Nkrumah, Esther; Fandrick, Keith; Edwards, Joan; Young, Peter R.

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases

MOLECULAR NEURODEGENERATION

IF17.5

2024-03-27

OAAI

Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; Deture, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjoern; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard

Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains 隐性外显子包含是衰老大脑中晚期NC的分子特征

ACTA NEUROPATHOLOGICA

IF9.3

2024-02-03

OAAI

Chung, Mingee; Carter, E. Kathleen; Veire, Austin M.; Dammer, Eric B.; Chang, Jianjun; Duong, Duc M.; Raj, Nisha; Bassell, Gary J.; Glass, Jonathan D.; Gendron, Tania F.; Nelson, Peter T.; Levey, Allan I.; Seyfried, Nicholas T.; Mceachin, Zachary T.

Fluid biomarkers for amyotrophic lateral sclerosis: a review

MOLECULAR NEURODEGENERATION

IF17.5

2024-01-24

OAAI

Irwin, Katherine E.; Sheth, Udit; Wong, Philip C.; Gendron, Tania F.

Immunological drivers of amyotrophic lateral sclerosis

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2023-11-08

PREAI

Gendron, Tania F.; Petrucelli, Leonard

Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit C9ORF72治疗额颞叶痴呆和肌萎缩性侧索硬化症的路线图: C9ORF72 FTD/ALS峰会报告

NEUROLOGY AND THERAPY

IF4.8

2023-10-17

OAAI

Sattler, Rita; Traynor, Bryan J.; Robertson, Janice; Van den Bosch, Ludo; Barmada, Sami J.; Svendsen, Clive N.; Disney, Matthew D.; Gendron, Tania F.; Wong, Philip C.; Turner, Martin R.; Boxer, Adam; Babu, Suma; Benatar, Michael; Kurnellas, Michael; Rohrer, Jonathan D.; Donnelly, Christopher J.; Bustos, Lynette M.; Van Keuren-Jensen, Kendall; Dacks, Penny A.; Sabbagh, Marwan N.

研究方向