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收藏Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells细胞内BAPTA直接抑制PFKFB3,从而阻碍mTORC1-driven Mcl-1翻译并杀死MCL-1-addicted癌细胞
Sneyers, Flore; Kerkhofs, Martijn; Speelman-Rooms, Femke; Welkenhuyzen, Kirsten; La Rovere, Rita; Shemy, Ahmed; Voet, Arnout; Eelen, Guy; Dewerchin, Mieke; Tait, Stephen W. G.; Ghesquiere, Bart; Bootman, Martin D.; Bultynck, Geert
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收藏Constitutive IP3 signaling underlies the sensitivity of B-cell cancers to the Bcl-2/IP3 receptor disruptor BIRD-2组成型IP3信号传导是b细胞癌对Bcl-2/IP3受体干扰物BIRD-2敏感性的基础
Bittremieux, Mart; La Rovere, Rita M.; Akl, Haidar; Martines, Claudio; Welkenhuyzen, Kirsten; Dubron, Kathia; Baes, Myriam; Janssens, Ann; Vandenberghe, Peter; Laurenti, Luca; Rietdorf, Katja; Morciano, Giampaolo; Pinton, Paolo; Mikoshiba, Katsuhiko; Bootman, Martin D.; Efremov, Dimitar G.; De Smedt, Humbert; Parys, Jan B.; Bultynck, Geert
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收藏Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes大鼠心室肌细胞中心肌肌球蛋白结合蛋白-C的PKC磷酸化调节对endothelin-1的收缩反应
Smyrnias, Ioannis; Goodwin, Normann; Wachten, Dagmar; Skogestad, Jonas; Aronsen, Jan Magnus; Robinson, Emma L.; Demydenko, Kateryna; Segonds-Pichon, Anne; Oxley, David; Sadayappan, Sakthivel; Sipido, Karin; Bootman, Martin D.; Roderick, H. Llewelyn
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收藏Basal ryanodine receptor activity suppresses autophagic flux基础ryanodine受体活性抑制自噬通量
Vervliet, Tim; Pintelon, Isabel; Welkenhuyzen, Kirsten; Bootman, Martin D.; Bannai, Hiroko; Mikoshiba, Katsuhiko; Martinet, Wim; Kasri, Nael Nadif; Parys, Jan B.; Bultynck, Geert
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