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Rationale and design of the MODIFY study: A phase 3 multicenter, double-blind, randomized, placebo-controlled, parallel-group study to determine the efficacy and safety of lucerastat oral monotherapy in adult subjects with Fabry disease Wanner, Christoph; Hughes, Derralynn; Kimonis, Virginia; Politei, Juan; Uceyler, Nurcan; Warnock, David G.; Cornelisse, Peter; Frey, Aline 分享 收藏
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Efficacy and Safety of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis A Randomized, Placebo-Controlled, Phase II Study Denton, Christopher P.; Hachulla, Eric; Riemekasten, Gabriela; Schwarting, Andreas; Frenoux, Jean-Marie; Frey, Aline; Le Brun, Franck-Olivier; Herrick, Ariane L. 分享 收藏
SELEXIPAG IN RAYNAUD'S PHENOMENON SECONDARY TO SYSTEMIC SCLEROSIS: A RANDOMISED, PLACEBO-CONTROLLED, PHASE II STUDY Denton, C. P.; Hachulla, E.; Riemekasten, G.; Schwarting, A.; Frenoux, J. -M.; Frey, A.; Le Brun, F. -O.; Herrick, A. 分享 收藏
Selexipag for the Treatment of Pulmonary Arterial Hypertension Sitbon, Olivier; Channick, Richard; Chin, Kelly M.; Frey, Aline; Gaine, Sean; Galie, Nazzareno; Ghofrani, Hossein-Ardeschir; Hoeper, Marius M.; Lang, Irene M.; Preiss, Ralph; Rubin, Lewis J.; Di Scala, Lilla; Tapson, Victor; Adzerikho, Igor; Liu, Jinming; Moiseeva, Olga; Zeng, Xiaofeng; Simonneau, Gerald; McLaughlin, Vallerie V. 分享 收藏
Effect of selexipag on long-term outcomes in key subgroups of patients with pulmonary arterial hypertension (PAH): GRIPHON study results Sitbon, Olivier; Channick, Richard; Chin, Kelly; Frey, Aline; Galie, Nazzareno; Ghofrani, Hossein-Ardeschir; Hoeper, Marius M.; Lang, Irene; Le Brun, Franck-Olivier; McLaughlin, Vallerie; Preiss, Ralph; Rubin, Lewis J.; Simonneau, Gerald; Tapson, Victor; Gaine, Sean 分享 收藏
Individualized Dosing of Selexipag Based on Tolerability in the GRIPHON Study Shows Consistent Efficacy and Safety in Patients With Pulmonary Arterial Hypertension (PAH) Channick, Richard; Chin, Kelly; Di Scala, Lilla; Frey, Aline; Preiss, Ralph; Gaine, Sean; Galie, Nazzareno; Ghofrani, Hossein Ardeschir; Hoeper, Marius; Lang, Irene; McLaughlin, Vallerie; Rubin, Lewis; Simonneau, Gerald; Sitbon, Olivier; Tapson, Victor 分享 收藏
Effect of Selexipag on Morbidity/Mortality in Pulmonary Arterial Hypertension: Results of the GRIPHON Study Galie, N.; Channick, R.; Chin, K.; Frey, A.; Gaine, S.; Ghofrani, A.; Hoeper, M.; Lang, I.; McLaughlin, V.; Preiss, R.; Rubin, L. J.; Sitbon, O.; Stefani, M.; Tapson, V.; Simonneau, G. 分享 收藏
Chronic heart failure and depression: anhedonia, motivation deficits, and functional brain changes in mice with myocardial infarction Popp, S.; Frey, A.; Siren, A. L.; Schmitt, A.; Hommers, L.; Ertl, G.; Lesch, K. P.; Frantz, S. 分享 收藏
Randomized Trial of Clazosentan in Patients With Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling Macdonald, R. Loch; Higashida, Randall T.; Keller, Emanuela; Mayer, Stephan A.; Molyneux, Andy; Raabe, Andreas; Vajkoczy, Peter; Wanke, Isabel; Bach, Doris; Frey, Aline; Nowbakht, Pegah; Roux, Sebastien; Kassell, Neal 分享 收藏
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Preventing Vasospasm Improves Outcome After Aneurysmal Subarachnoid Hemorrhage: Rationale and Design of CONSCIOUS-2 and CONSCIOUS-3 Trials 预防血管痉挛可改善动脉瘤性蛛网膜下腔出血后的预后: 意识2和意识3试验的原理和设计 Macdonald, R. Loch; Higashida, Randall T.; Keller, Emanuela; Mayer, Stephan A.; Molyneux, Andy; Raabe, Andreas; Vajkoczy, Peter; Wanke, Isabel; Frey, Aline; Marr, Angelina; Roux, Sebastien; Kassell, Neal F. 分享 收藏
Early Worsening Heart Failure in Patients Admitted for Acute Heart Failure: Time Course, Hemodynamic Predictors, and Outcome Torre-Amione, Guillermo; Milo-Cotter, Olga; Kaluski, Edo; Perchenet, Loic; Kobrin, Isaac; Frey, Aline; Rund, Michele M.; Weatherley, Beth Davison; Cotter, Gad 分享 收藏
Clazosentan to Overcome Neurological Ischemia and Infarction Occurring After Subarachnoid Hemorrhage (CONSCIOUS-1) Randomized, Double-Blind, Placebo-Controlled Phase 2 Dose-Finding Trial Clazosentan克服蛛网膜下腔出血后发生的神经缺血和梗塞 (considious-1) 随机,双盲,安慰剂对照的2期剂量发现试验 Macdonald, R. Loch; Kassell, Neal F.; Mayer, Stephan; Ruefenacht, Daniel; Schmiedek, Peter; Weidauer, Stephan; Frey, Aline; Roux, Sebastien; Pasqualin, Alberto 分享 收藏