Alex Loukas - Publications, H-index & Citations

Alex Loukas

james cook university

88H指数

481论文数

2.8W被引数

收录论文 237

发表时间

Optimized hookworm-derived biologic, AIP-2NTQ48 restores mucosal tolerance and down-regulates colon cancer-associated gene expression in TNBS-induced colitis 优化的钩虫衍生生物制剂AIP-2NTQ48恢复了黏膜耐受性，并下调了TNBS诱导的结肠炎中结肠癌相关基因的表达。

Mucosal Immunology

IF7.6

2026-03-09

OAAI

Yan Lu; Adrian Ilich; Ivana B. Ferreira; Rachael Y.M. Ryan; Darren A. Pickering; Sally Troy; Sharon M. Hoyte; Rebecca L. Johnston; Yide Wong; Alex Loukas; Severine Navarro

Functional characterization of secreted Schistosoma mansoni serpin SmSPI reveals Factor XIIa inhibition as evidenced by biochemical, and human plasma assays and supported by AI-assisted structural modelling 分泌型日本血吸虫丝氨酸蛋白酶抑制剂SmSPI的功能表征揭示其具有因子XIIa抑制活性，这一发现由生化实验和人类血浆检测证实，并得到AI辅助结构建模的支持。

International Journal for Parasitology

IF3.2

2026-02-20

OAAI

Lukáš Konečný; Kristýna Peterková; Ingrid Hrachovinová; Alex Loukas; Tomáš Macháček; Jan Dvořák; Lucie Jedličková

Lipoprotein Association Fluorometry (LAF) as a Semi-Quantitative Characterization Tool to Assess Extracellular Vesicle-Lipoprotein Binding 脂蛋白关联荧光测定法（LAF）作为一种半定量表征工具，用于评估细胞外囊泡与脂蛋白的结合。

JOURNAL OF EXTRACELLULAR VESICLES

IF14.5

2025-09-30

OAAI

Ghebosu, Raluca; Goncalves, Jenifer Pendiuk; Fitri, Nur Indah; Iannotta, Dalila; Sharifpour, Mohammad Farouq; Coleborn, Elaina; Loukas, Alex; Souza-Fonseca-Guimaraes, Fernando; Wolfram, Joy

Serological assessment of pediatric parasite exposure in two Senegalese districts using multiplex serology 利用多重血清学方法对塞内加尔两个行政区儿童寄生虫暴露情况进行血清学评估

Current Research in Parasitology & Vector-Borne Diseases

IF3.1

2025-09-19

OAAI

Helena Brazal Monzó; Santiago Rayment Gomez; Doudou Sow; Aminata Colle Lo; Marie Pierre Diouf; Amadou Seck; Ibrahima Mbaye; Elhadji Babacar Fall; Catriona Patterson; Seyi Soremekun; Isaac A. Manga; Cheikh Cissé; Awa Diouf; Ndéye Aida Gaye; Kevin K.A. Tetteh; Alex Loukas; Brian Greenwood; Jean Louis A. Ndiaye; Chris Drakeley; Muhammed O. Afolabi

Gene Editing of a Carcinogenic Liver Fluke Tetraspanin Impairs Parasite Surface Biogenesis and Extracellular Vesicle Uptake by Human Host Cells 致癌肝吸虫四跨膜蛋白的基因编辑破坏了寄生虫表面生物发生和人类宿主细胞对细胞外囊泡的摄取

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2025-09-01

OAAI

Chaiyadet, Sujittra; Ittiprasert, Wannaporn; Smout, Michael J.; Khowawisetsut, Ladawan; Ruangsuwast, Apisit; Brindley, Paul J.; Loukas, Alex; Laha, Thewarach

Development of an efficacious oral peptide vaccine against infection with the carcinogenic liver fluke Opisthorchis viverrini 开发一种有效预防致癌肝吸虫 Opisthorchis viverrini 感染的口服多肽疫苗

Vaccine

IF3.5

2025-07-08

PREAI

Wuttipong Phumrattanaprapin; Ahmed O. Shalash; Mariusz Skwarczynski; Michael J. Smout; Thewarach Laha; Istvan Toth; Alex Loukas

Topological isomers of a potent wound healing peptide: Structural insights and implications for bioactivity 一种强效伤口愈合肽的拓扑异构体：结构洞察及其对生物活性的影响

Journal of Biological Chemistry

IF3.9

2025-07-01

OAAI

Tiziano Raffaelli; David T. Wilson; Mehdi Mobli; Michael J. Smout; Guangzu Zhao; Rozita Takjoo; Paramjit S. Bansal; Rilei Yu; Zixuan Zhang; Alex Loukas; Norelle L. Daly

Australian tropical medicinal plants and their phytochemicals with wound healing and antidiabetic properties 澳大利亚热带药用植物及其具有伤口愈合和抗糖尿病活性的植物化学物质

PHYTOCHEMISTRY REVIEWS

IF7.6

2025-05-23

OAAI

Handa Muliasari; Karma Yeshi; Michael Oelgemöller; Alex Loukas; Darren Crayn; Phurpa Wangchuk

The Anthelmintic Activity of Stonefish (Synanceia spp.) Ichthyocrinotoxins and Their Potential as Novel Therapeutics

TOXINS

IF4

2025-02-02

OAAI

Lennox-Bulow, Danica; Seymour, Jamie; Loukas, Alex; Smout, Michael

Proteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum

PLOS NEGLECTED TROPICAL DISEASES

IF3.4

2025-01-20

OAAI

Wong, Yide; Rosa, Bruce A.; Becker, Luke; Camberis, Mali; Legros, Graham; Zhan, Bin; Bottazzi, Maria Elena; Fujiwara, Ricardo T.; Ritmejeryte, Edita; Laha, Thewarach; Chaiyadet, Sujittra; Taweethavonsawat, Piyanan; Brindley, Paul J.; Bracken, Bethany K.; Giacomin, Paul R.; Mitreva, Makedonka; Loukas, Alex

Mechanistic insights into liver-fluke-induced bile-duct cancer

Trends in Parasitology

IF6.6

2024-12-01

PREAI

Smout, Michael J.; Laha, Thewarach; Chaiyadet, Sujittra; Brindley, Paul J.; Loukas, Alex

Hookworm vaccines: current and future directions

EXPERT REVIEW OF VACCINES

IF4.8

2024-11-15

OAAI

Sarkar, Eti R.; Sikder, Suchandan; Giacomin, Paul; Loukas, Alex

Ulcerative colitis: clinical biomarkers, therapeutic targets, and emerging treatments

TRENDS IN PHARMACOLOGICAL SCIENCES

IF19.9

2024-10-01

PREAI

Wangchuk, Phurpa; Yeshi, Karma; Loukas, Alex

Controlled human hookworm infection remodels plasmacytoid dendritic cells and regulatory T cells towards profiles seen in natural infections in endemic areas

NATURE COMMUNICATIONS

IF15.7

2024-07-16

OAAI

Manurung, Mikhael D.; Sonnet, Friederike; Hoogerwerf, Marie-Astrid; Janse, Jacqueline J.; Kruize, Yvonne; Bes-Roeleveld, Laura de; Konig, Marion; Loukas, Alex; Dewals, Benjamin G.; Supali, Taniawati; Jochems, Simon P.; Roestenberg, Meta; Coppola, Mariateresa; Yazdanbakhsh, Maria

Pharmaceutical Potential of Remedial Plants and Helminths for Treating Inflammatory Bowel Disease

PHARMACEUTICALS

IF4.8

2024-06-21

OAAI

Jamtsho, Tenzin; Loukas, Alex; Wangchuk, Phurpa

Regulation of host metabolic health by parasitic helminths

Trends in Parasitology

IF6.6

2024-05-01

PREAI

Sikder, Suchandan; Pierce, Doris; Sarkar, Eti R.; McHugh, Connor; Quinlan, Kate G. R.; Giacomin, Paul; Loukas, Alex

Structural analysis of a U-superfamily conotoxin containing a mini-granulin fold: Insights into key features that distinguish between the ICK and granulin folds

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2024-04-01

OAAI

Raffaelli, Tiziano; Wilson, David T.; Dutertre, Sebastien; Giribaldi, Julien; Vetter, Irina; Robinson, Samuel D.; Thapa, Ashvriya; Widi, Antin; Loukas, Alex; Daly, Norelle L.

Approaches, Strategies and Procedures for Identifying Anti-Inflammatory Drug Lead Molecules from Natural Products

PHARMACEUTICALS

IF4.8

2024-02-22

OAAI

Jamtsho, Tenzin; Yeshi, Karma; Perry, Matthew J.; Loukas, Alex; Wangchuk, Phurpa

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation (vol 21, pg 1205, 2020)

NATURE IMMUNOLOGY

IF27.6

2024-02-15

OAAI

Ng, Susanna S.; De Labastida Rivera, Fabian; Yan, Juming; Corvino, Dillon; Das, Indrajit; Zhang, Ping; Kuns, Rachel; Chauhan, Shashi Bhushan; Hou, Jiajie; Li, Xian-Yang; Frame, Teija C. M.; Mcenroe, Benjamin A.; Moore, Eilish; Na, Jinrui; Engel, Jessica A.; Soon, Megan S. F.; Singh, Bhawana; Kueh, Andrew J.; Herold, Marco J.; Montes de Oca, Marcela; Singh, Siddharth Sankar; Bunn, Patrick T.; Aguilera, Amy Roman; Casey, Mika; Braun, Matthias; Ghazanfari, Nazanin; Wani, Shivangi; Wang, Yulin; Amante, Fiona H.; Edwards, Chelsea L.; Haque, Ashraful; Dougall, William C.; Singh, Om Prakash; Baxter, Alan G.; Teng, Michele W. L.; Loukas, Alex; Daly, Norelle L.; Cloonan, Nicole; Degli-Esposti, Mariapia A.; Uzonna, Jude; Heath, William R.; Bald, Tobias; Tey, Siok-Keen; Nakamura, Kyohei; Hill, Geoffrey R.; Kumar, Rajiv; Sundar, Shyam; Smyth, Mark J.; Engwerda, Christian R.

Effect of experimental hookworm infection on insulin resistance in people at risk of type 2 diabetes 实验性钩虫感染对2型糖尿病高危人群胰岛素抵抗的影响

NATURE COMMUNICATIONS

IF15.7

2023-07-26

OAAI

Pierce, Doris R.; McDonald, Malcolm; Merone, Lea; Becker, Luke; Thompson, Fintan; Lewis, Chris; Ryan, Rachael Y. M.; Hii, Sze Fui; Zendejas-Heredia, Patsy A.; Traub, Rebecca J.; Field, Matthew A.; Rahman, Tony; Croese, John; Loukas, Alex; McDermott, Robyn; Giacomin, Paul R.

研究方向