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K

Kyle L. Kolaja

roche holding

37H指数
90论文数
5.3K被引数
收录论文 37
发表时间
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SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site studySACF和GILA用于体外评估CRISPR/Cas9编辑的细胞治疗候选物的转化能力：一项多中心研究
errGene Therapy
IF4.5
err2026-07-29
err0
errOAAI
errLena Dorsheimer; Joana Rita Ferreira; Bojing Wang; Rebecca Bohnert; Rashade Haynes II; Sabine Kaiser; Andreas Neerincx; Corinna Smolarek; Louise Delsing; Benoit Fischer; Stefanie Könen; Andreas Schulz; Kyle L. Kolaja; Ridhirama Bhuwania; Connie L. Chen; Lucilia Pereira Mouriès; Mick Fellows; Silvana Libertini; Myriam Lemmens
err分享
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Immunogenicity Risk Assessment of Process-Related Impurities in An Engineered T Cell Receptor Cellular Product
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-08-01
err0
PREAI
errMora, Johanna; Forman, Daron; Hu, Jennifer; Ijantkar, Akshata; Gokemeijer, Jochem; Kolaja, Kyle L.; Picarillo, Caryn; Jawa, Vibha; Yue, Hai; Lamy, Juliette; Denies, Sofie; Schockaert, Jana; Ackaert, Chloe
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A functional three-dimensional microphysiological human model of myeloma bone disease
errJOURNAL OF BONE AND MINERAL RESEARCH
IF5.9
err2021-06-25
err13
errOAAI
errVisconti, Richard J.; Kolaja, Kyle; Cottrell, Jessica A.
err分享
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Investigation Into the Role of ERK in Tyrosine Kinase Inhibitor-Induced Neuropathy
errTOXICOLOGICAL SCIENCES
IF4.1
err2021-03-22
err6
PREAI
errBelair, David G.; Sudak, Katelyn; Connelly, Kimberly; Collins, Nathaniel D.; Kopytek, Stephan J.; Kolaja, Kyle L.
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Cardiovascular microphysiological systems (CVMPS) for safety studies - a pharma perspective
errLAB ON A CHIP
IF5.4
err2021-01-01
err15
PREAI
errPointon, Amy; Maher, Jonathan; Davis, Myrtle; Baker, Thomas; Cichocki, Joseph; Ramsden, Diane; Hale, Christopher; Kolaja, Kyle L.; Levesque, Paul; Sura, Radhakrishna; Stresser, David M.; Gintant, Gary
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Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspective
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2020-11-01
err2
PREAI
errReynolds, Vincent L.; Butler, Paul; Abernathy, Matthew M.; Aschenbrenner, Laura; Best, Derek D.; Blank, Jim; Crosby, Meredith; Custer, Laura; Escobar, Patricia A.; Kolaja, Kyle; Moggs, Jonathan; Shuey, Dana; Snyder, Chelsea; Van Vleet, Terry; Zhou, Junguo; Hart, Timothy K.
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Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4
errSCIENTIFIC REPORTS
IF3.9
err2020-02-18
err25
errOAAI
errBelair, David G.; Lu, Gang; Waller, Laura E.; Gustin, Jason A.; Collins, Nathaniel D.; Kolaja, Kyle L.
err分享
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Developing in vitro assays to transform gastrointestinal safety assessment: potential for microphysiological systems
errLAB ON A CHIP
IF5.4
err2020-01-01
err57
errOAAI
errPeters, Matthew F.; Choy, Allison L.; Pin, Carmen; Leishman, Derek J.; Moisan, Annie; Ewart, Lorna; Guzzie-Peck, Peggy J.; Sura, Radhakrishna; Keller, Douglas A.; Scott, Clay W.; Kolaja, Kyle L.
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Cardiovascular Toxicity Induced by Kinase Inhibitors: Mechanisms and Preclinical Approaches
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2019-12-16
err53
errOAAI
errLamore, Sarah D.; Kohnken, Rebecca A.; Peters, Matthew F.; Kolaja, Kyle L.
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A comparison of 24 chemicals in the six-well bacterial reverse mutation assay to the standard 100-mm Petri plate bacterial reverse mutation assay in two laboratories
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2018-12-01
err5
PREAI
errNicolette, J.; Dakoulas, E.; Pant, K.; Crosby, M.; Kondratiuk, A.; Murray, J.; Sonders, P.; Kulkarni, R.; Jayakumar, G.; Mathur, M.; Patel, A.; Vicente, R.; Datta, K.; Kolaja, K.
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Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells
errCELL REPORTS
IF6.9
err2014-11-01
err213
errOAAI
errDrawnel, Faye M.; Boccardo, Stefano; Prummer, Michael; Delobel, Frederic; Graff, Alexandra; Weber, Michael; Gerard, Regine; Badi, Laura; Kam-Thong, Tony; Bu, Lei; Jiang, Xin; Hoflack, Jean-Christophe; Kiialainen, Anna; Jeworutzki, Elena; Aoyama, Natsuyo; Carlson, Coby; Burcin, Mark; Gromo, Gianni; Boehringer, Markus; Stahlberg, Henning; Hall, Benjamin J.; Magnone, Maria Chiara; Kolaja, Kyle; Chien, Kenneth R.; Bailly, Jacques; Iacone, Roberto
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Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line
errCARDIOVASCULAR TOXICOLOGY
IF3.7
err2014-08-19
err81
PREAI
errPeters, Matthew F.; Lamore, Sarah D.; Guo, Liang; Scott, Clay W.; Kolaja, Kyle L.
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Stem Cells and Stem Cell-derived Tissues and Their Use in Safety Assessment
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2014-02-01
err28
errOAAI
errKolaja, Kyle
err分享
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A High-Throughput Screen for Teratogens Using Human Pluripotent Stem Cells
errTOXICOLOGICAL SCIENCES
IF4.1
err2013-10-23
err65
errOAAI
errKameoka, Sei; Babiarz, Joshua; Kolaja, Kyle; Chiao, Eric
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Refining the Human iPSC-Cardiomyocyte Arrhythmic Risk Assessment Model
errTOXICOLOGICAL SCIENCES
IF4.1
err2013-09-18
err111
errOAAI
errGuo, Liang; Coyle, Luke; Abrams, Rory M. C.; Kemper, Raymond; Chiao, Eric T.; Kolaja, Kyle L.
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Investigation of mechanism of drug-induced cardiac injury and torsades de pointes in cynomolgus monkeys食蟹猴药物性心脏损伤和尖端扭转的机制研究
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2012-03-23
err10
errOAAI
errMisner, D. L.; Frantz, C.; Guo, L.; Gralinski, M. R.; Senese, P. B.; Ly, J.; Albassam, M.; Kolaja, K. L.
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Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations使用人类干细胞衍生的心肌细胞检查舒尼替尼介导的心脏毒性和电生理改变
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2011-11-01
err77
errOAAI
errCohen, J. D.; Babiarz, J. E.; Abrams, R. M.; Guo, L.; Kameoka, S.; Chiao, E.; Taunton, J.; Kolaja, K. L.
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HPLC-MS/MS methods for the quantitative analysis of 5-oxoproline (pyroglutamate) in rat plasma and hepatic cell line culture medium
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2011-11-01
err33
PREAI
errGeenen, Suzanne; Guallar-Hoyas, Cristina; Michopoulos, Filippos; Kenna, J. Gerry; Kolaja, Kyle L.; Westerhoff, Hans V.; Thomas, Paul; Wilson, Ian D.
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Estimating the Risk of Drug-Induced Proarrhythmia Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes使用人诱导多能干细胞衍生的心肌细胞评估药物诱导的心律失常的风险
errTOXICOLOGICAL SCIENCES
IF4.1
err2011-06-20
err242
errOAAI
errGuo, Liang; Abrams, Rory M. C.; Babiarz, Joshua E.; Cohen, Jennifer D.; Kameoka, Sei; Sanders, Martin J.; Chiao, Eric; Kolaja, Kyle L.
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HPLC-MS/MS methods for the quantitative analysis of ophthalmic acid in rodent plasma and hepatic cell line culture medium
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2011-04-01
err18
PREAI
errGeenen, Suzanne; Michopoulos, Filippos; Kenna, J. Gerry; Kolaja, Kyle L.; Westerhoff, Hans V.; Wilson, Ian
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研究方向

暂无研究方向
合作学者
合作期刊
K
Kenneth R. Chien
H 指数: 129 · 论文数: 406
C
Curtis D. Klaassen
H 指数: 116 · 论文数: 1.2K
H
Hans V. Westerhoff
H 指数: 92 · 论文数: 715
J
Jack Taunton
H 指数: 91 · 论文数: 438
I
Ian D. Wilson
H 指数: 82 · 论文数: 561
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