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Takashi Saito

The University of Tokyo

70H指数
537论文数
1.7W被引数
收录论文 167
发表时间
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Assessment of the Association of Periodontitis and Diabetes Mellitus with Alzheimer’s Disease in a Mouse Model评估牙周炎和糖尿病与阿尔茨海默病相关性的小鼠模型研究
errInternational Journal of Molecular Sciences
IF4.9
err2026-08-27
err0
errOAAI
errMomoko Nakahara; Kota Kataoka; Takayuki Maruyama; Mohammad Nurhamim; Yixuan Zhang; Daiki Fukuhara; Yoko Uchida-Fukuhara; Md Monirul Islam; Manabu Morita; Takashi Saito; Daisuke Ekuni
err分享
err收藏
Cryo-EM structure of pro-aggregant P301L/S320F double-mutant tau filaments formed in mouse brains following peripheral AAV delivery经外周AAV递送后在小鼠脑中形成的促聚集P301L/S320F双突变tau丝的冷冻电镜结构
errActa Neuropathologica Communications
IF5.7
err2026-08-13
err0
errOAAI
errMaria Kano; Taeko Kimura; Haruaki Yanagisawa; Komei Yamashita; Lisa Tatsumi; Asahi Sakai; Xinyi Li; Takaomi C. Saido; Takashi Saito; Sho Takatori; Masahide Kikkawa; Taisuke Tomita
err分享
err收藏
CXCL10 contributes to female-specific pathological progression in tauopathy model miceCXCL10参与tau病模型小鼠中性别特异的病理进展
errJournal of Neuroinflammation
IF10.1
err2026-08-05
err0
errOAAI
errRyohei Uenishi; Rinna Kawata; Tatsuya Manabe; Yukio Matsuba; Naomi Mihira; Toru Takeo; Takaomi C. Saido; Masanori Hijioka; Takashi Saito
err分享
err收藏
Early and progressive retinal microglial changes in APPNL-F/NL-F mouse model of Alzheimer’s disease revealed by an automated image analysis software通过自动图像分析软件揭示的appnl-f/nl-f小鼠阿尔茨海默氏病模型的早期和进行性视网膜小胶质细胞变化
errFrontiers in Aging Neuroscience
IF4.5
err2026-01-30
err0
errOAAI
errLidia Sánchez-Puebla†; Inés López-Cuenca†; Miguel A. Sánchez-Puebla†; Ana Granados; Ana I. Ramírez; Juan Llorens; Takaomi C. Saido; Takashi Saito; Carmen Nieto-Vaquero; María A. Moro; Valentín Moreno; José M. Ramírez; Rosa de Hoz
err分享
err收藏
Somatostatin receptor subtypes 1 and 4 regulate neprilysin, the major amyloid-β degrading enzyme in brain生长抑素受体亚型1和4调节脑内主要的淀粉样蛋白-β降解酶——中性内肽酶。
errJournal of Alzheimer’s Disease
IF0
err2025-11-19
err0
PREAI
errPer Nilsson; Karin Sörgjerd; Naomasa Kakiya; Hiroki Sasaguri; Naoto Watamura; Lovisa Johansson; Makoto Shimozawa; Satoshi Tsubuki; Zhulin Zhou; Raul Loera-Valencia; Risa Takamura; Misaki Sekiguchi; Aline Pegel; Stefan Schulz; Takashi Saito; Nobuhisa Iwata; Bengt Winblad; Takaomi C Saido
err分享
err收藏
A decade progress in the phenotyping of AppNL-G-F knock-in mouse model of Alzheimer's disease十年间阿尔茨海默病AppNL-G-F基因敲入小鼠模型的表型研究进展
errNEUROSCIENCE RESEARCH
IF3.4
err2025-09-01
err0
errOAAI
errManabe, Tatsuya; Saito, Takashi
err分享
err收藏
High-Fat Diet-Induced Excessive Accumulation of Cerebral Cholesterol Esters and Microglial Dysfunction Exacerbate Alzheimer's Disease Pathology in APPNL-G-F mice高脂饮食诱导的脑内胆固醇酯过度积累和小胶质细胞功能障碍加剧APPNL-G-F小鼠的阿尔茨海默病病理。
errMOLECULAR NEUROBIOLOGY
IF4.3
err2025-05-17
err0
errOAAI
errYang, Shuhan; Miyazaki, Hirofumi; Wannakul, Tunyanat; Amo, Eiko; Saido, Takaomi; Saito, Takashi; Sasaguri, Hiroki; Maekawa, Motoko; Owada, Yuji
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Long-term systemic androgen deprivation partially modulates neuroinflammation in male AppNL-G-F/NL-G-F mice长期系统性雄激素剥夺部分调节了雄性AppNL-G-F/NL-G-F小鼠的神经炎症
errSCIENTIFIC REPORTS
IF3.9
err2025-04-27
err0
errOAAI
errMaekawa, Kasumi; Sobue, Akira; Komine, Okiru; Saito, Yuko; Murayama, Shigeo; Saido, Takaomi C.; Saito, Takashi; Yamanaka, Koji
err分享
err收藏
Comparative retinal study by OCT in Alzheimer's disease: Insights from the app NL-F/NL-F model阿尔茨海默病中通过OCT进行的比较视网膜研究：来自NL-F/NL-F模型的见解
errACTA OPHTHALMOLOGICA
IF2.8
err2025-01-19
err0
PREAI
errSanchez-Puebla, L; Lopez-Cuenca, I; Vazquez, AA; Salobrar-Garcia, E; Matamoros, JA; Lozano, MPR; Fernandez-Albarral, JA; Elvira-Hurtado, L; Ramirez, AI; Salazar, JJ; Saido, T; Saito, T; Nieto-Vaquero, C; Cuartero, MI; Moro, MA; de Hoz, R; Ramirez, JM
err分享
err收藏
Assessing retinal thickness and vascular structures in an Alzheimer's disease mouse model APP NL-F/NL-F评估阿尔茨海默病小鼠模型APP NL-F/NL-F的视网膜厚度和血管结构
errACTA OPHTHALMOLOGICA
IF2.8
err2025-01-19
err0
PREAI
errSanchez-Puebla, L; López-Cuenca, I; Jiménez, MG; Salobrar-Garcia, E; Matamoros, JA; Lozano, MPR; Fernández-Albarral, JA; Elvira-Hurtado, L; Ramirez, AI; Salazar, JJ; Nieto-Vaquero, C; Desviat, MIC; Moro, MA; Saito, T; Saido, TC; Ramirez, JM; de Hoz, R
err分享
err收藏
Comparative retinal study by OCT in Alzheimer's disease: Insights from the APP NL-F/NLF model阿尔茨海默病中OCT的比较视网膜研究：来自APP NL-F/NLF模型的见解
errACTA OPHTHALMOLOGICA
IF2.8
err2025-01-19
err0
PREAI
errSanchez-Puebla, L; López-Cuenca, I; Vázquez, AA; Salobrar-Garcia, E; Matamoros, JA; Lozano, MPR; Fernández-Albarral, JA; Elvira-Hurtado, L; Ramirez, AI; Salazar, JJ; Saido, T; Saito, T; Nieto-Vaquero, C; Cuartero, MI; Moro, MA; de Hoz, R; Ramirez, JM
err分享
err收藏
Assessing retinal thickness and vascular structures in an Alzheimer's disease mouse model app NL-F/NL-F评估阿尔茨海默病小鼠模型中视网膜厚度和血管结构的app NL-F/NL-F
errACTA OPHTHALMOLOGICA
IF2.8
err2025-01-19
err0
PREAI
errSanchez-Puebla, L; Lopez-Cuenca, I; Jimenez, MG; Salobrar-Garcia, E; Matamoros, JA; Lozano, MPR; Fernandez-Albarral, JA; Elvira-Hurtado, L; Ramirez, AI; Salazar, JJ; Nieto-Vaquero, C; Desviat, MIC; Moro, MA; Saito, T; Saido, TC; Ramirez, JM; de Hoz, R
err分享
err收藏
Fingolimod treatment exacerbates tau phosphorylation and neurodegeneration in a mouse model of tauopathy with accumulated brain CD8+ T cells芬戈莫德治疗加剧了在具有累积脑CD8+ T细胞的tau蛋白病小鼠模型中的tau蛋白磷酸化及神经退行。
errBRAIN COMMUNICATIONS
IF4.5
err2025-01-01
err0
PREAI
errUenishi, Ryohei; Kawata, Rinna; Manabe, Tatsuya; Takeo, Toru; Hijioka, Masanori; Saito, Takashi
err分享
err收藏
GLP-1 receptor signaling restores aquaporin 4 subcellular polarization in reactive astrocytes and promotes amyloid β clearance in a mouse model of Alzheimer's diseaseGLP-1受体信号通路恢复了反应性星形胶质细胞中水通道蛋白4的亚细胞极化，并促进了阿尔茨海默病小鼠模型中β-淀粉样蛋白的清除。
errBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
IF2.2
err2024-12-01
err1
errOAAI
errSasaki, Kana; Fujita, Hiroki; Sato, Takehiro; Kato, Shunske; Takahashi, Yuya; Takeshita, Yukio; Kanda, Takashi; Saito, Takashi; Saido, Takamori C.; Hattori, Satoko; Hozumi, Yasukazu; Yamada, Yuichiro; Waki, Hironori
err分享
err收藏
Microglial cannabinoid receptor type II stimulation improves cognitive impairment and neuroinflammation in Alzheimer's disease mice by controlling astrocyte activation
errCELL DEATH & DISEASE
IF9.6
err2024-11-26
err1
errOAAI
errSobue, Akira; Komine, Okiru; Endo, Fumito; Kakimi, Chihiro; Miyoshi, Yuka; Kawade, Noe; Watanabe, Seiji; Saito, Yuko; Murayama, Shigeo; Saido, Takaomi C.; Saito, Takashi; Yamanaka, Koji
err分享
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Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models机器学习在人源化和转基因阿尔茨海默病模型中揭示了显着的自发行为变化和治疗效果
errCELL REPORTS
IF6.9
err2024-11-01
err0
errOAAI
errMiller, Stephanie R.; Luxem, Kevin; Lauderdale, Kelli; Nambiar, Pranav; Honma, Patrick S.; Ly, Katie K.; Bangera, Shreya; Bullock, Mary; Shin, Jia; Kaliss, Nick; Qiu, Yuechen; Cai, Catherine; Shen, Kevin; Mallen, K. Dakota; Yan, Zhaoqi; Mendiola, Andrew S.; Saito, Takashi; Saido, Takaomi C.; Pico, Alexander R.; Thomas, Reuben; Roberson, Erik D.; Akassoglou, Katerina; Bauer, Pavol; Remy, Stefan; Palop, Jorge J.
err分享
err收藏
Metabolic resistance of Aβ3pE-42, a target epitope of the anti-Alzheimer therapeutic antibody, donanemab
errLIFE SCIENCE ALLIANCE
IF2.9
err2024-09-30
err0
errOAAI
errIwata, Nobuhisa; Tsubuki, Satoshi; Sekiguchi, Misaki; Watanabe-Iwata, Kaori; Matsuba, Yukio; Kamano, Naoko; Fujioka, Ryo; Takamura, Risa; Watamura, Naoto; Kakiya, Naomasa; Mihira, Naomi; Morito, Takahiro; Shirotani, Keiro; Mann, David M. A.; Robinson, Andrew C.; Hashimoto, Shoko; Sasaguri, Hiroki; Saito, Takashi; Higuchi, Makoto; Saido, Takaomi C.
err分享
err收藏
Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging
errSCIENTIFIC REPORTS
IF3.9
err2024-08-09
err0
errOAAI
errHonda, Keiko; Takahashi, Hiroo; Hata, Saori; Abe, Ruriko; Saito, Takashi; Saido, Takaomi C.; Taru, Hidenori; Sobu, Yuriko; Ando, Kanae; Yamamoto, Tohru; Suzuki, Toshiharu
err分享
err收藏
The dopaminergic system promotes neprilysin-mediated degradation of amyloid-β in the brain
errSCIENCE SIGNALING
IF6.6
err2024-08-06
err5
PREAI
errWatamura, Naoto; Kakiya, Naomasa; Fujioka, Ryo; Kamano, Naoko; Takahashi, Mika; Nilsson, Per; Saito, Takashi; Iwata, Nobuhisa; Fujisawa, Shigeyoshi; Saido, Takaomi C.
err分享
err收藏
Preventive effect of propolis on cognitive decline in Alzheimer's disease model mice
errNEUROBIOLOGY OF AGING
IF3.5
err2024-07-01
err2
errOAAI
errInagaki, Ryo; Yamakuni, Tohru; Saito, Takashi; Saido, Takaomi C.; Moriguchi, Shigeki
err分享
err收藏

研究方向

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合作学者
合作期刊
J
John Q. Trojanowski
H 指数: 255 · 论文数: 1.8K
M
Mark P. Mattson
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J
John Hardy
H 指数: 207 · 论文数: 1.9K
V
Virginia M.‐Y. Lee
H 指数: 200 · 论文数: 920
M
Masayuki Yamamoto
H 指数: 193 · 论文数: 2.1K
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