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T

Takaomi C. Saido

riken center for brain science
H指数:112
被引数:5.0万

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APOE3 and APOE4 human astrocytes differentially modulate Alzheimer's disease pathology and microglial responses in chimeric mice

APOE3和APOE4人星形胶质细胞在嵌合小鼠中差异调节阿尔茨海默病病理和微胶质细胞反应

Cell Reports
IF6.9
2026-08-010
OAAI
Cruz-Sese, Joan; Miron-Alcala, Marta; Alfonso-Triguero, Maria; Olalde, Jon; Ruiz, Leire; Galbis-Gramage, Nuria; Cortes, Lorea; Escobar, Laura; Preman, Pranav; Snellinx, An; Saito, Takashi; Saido, Takaomi C.; Saiz-Auz, Laura; Rabano-Gutierrez, Alberto; Aransay, Ana M.; Diez, Ibai; Tcw, Julia; Goate, Alison; De Strooper, Bart; Alberdi, Elena; Arranz, Amaia M.
Involvement of orexin nerves in early stage of Alzheimer's disease model mice and preventive effect of orexin receptor antagonists

阿片促黑素皮质素原神经在阿尔茨海默病模型小鼠早期阶段的参与及阿片促黑素皮质素原受体拮抗剂的预防作用

Journal of Alzheimer’s Disease
IF0
2026-03-120
PRE
Kazuhiro Hada; Yuki Murata; Yoshiaki Ohi; Sana Hashimoto; Hinata Watanabe; Kayoko Ozeki; Takaomi C. Saido; Takashi Saito; Hiroki Sasaguri; Hiroyuki Mizoguchi; Kiyofumi Yamada; Yoshifumi Wakiya
Early and progressive retinal microglial changes in APPNL-F/NL-F mouse model of Alzheimer’s disease revealed by an automated image analysis software

通过自动图像分析软件揭示的appnl-f/nl-f小鼠阿尔茨海默氏病模型的早期和进行性视网膜小胶质细胞变化

Frontiers in Aging Neuroscience
IF4.5
2026-01-300
OAAI
Lidia Sánchez-Puebla†; Inés López-Cuenca†; Miguel A. Sánchez-Puebla†; Ana Granados; Ana I. Ramírez; Juan Llorens; Takaomi C. Saido; Takashi Saito; Carmen Nieto-Vaquero; María A. Moro; Valentín Moreno; José M. Ramírez; Rosa de Hoz
Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrils

GPR34的选择性激动作用可刺激小胶质细胞对淀粉样β纤维的摄取和清除。

Alzheimer's Research & Therapy
IF7.6
2025-11-210
OAAI
Hayato Etani; Sho Takatori; Wenbo Wang; Jumpei Omi; Yusuke Amiya; Aika Akahori; Hirotaka Watanabe; Iki Sonn; Hideyuki Okano; Norikazu Hara; Mai Hasegawa; Akinori Miyashita; Masataka Kikuchi; Takeshi Ikeuchi; Maho Morishima; Yuko Saito; Shigeo Murayama; Takashi Saito; Takaomi C. Saido; Toshiyuki Takai; Tomohiko Ohwada; Junken Aoki; Taisuke Tomita
Somatostatin receptor subtypes 1 and 4 regulate neprilysin, the major amyloid-β degrading enzyme in brain

生长抑素受体亚型1和4调节脑内主要的淀粉样蛋白-β降解酶——中性内肽酶。

Journal of Alzheimer’s Disease
IF0
2025-11-190
PRE
Per Nilsson; Karin Sörgjerd; Naomasa Kakiya; Hiroki Sasaguri; Naoto Watamura; Lovisa Johansson; Makoto Shimozawa; Satoshi Tsubuki; Zhulin Zhou; Raul Loera-Valencia; Risa Takamura; Misaki Sekiguchi; Aline Pegel; Stefan Schulz; Takashi Saito; Nobuhisa Iwata; Bengt Winblad; Takaomi C Saido
APOE4-APP interactions exert early influences on cerebrovascular structure and function: implications for Alzheimer’s disease

APOE4-APP相互作用对脑血管结构和功能产生早期影响：对阿尔茨海默病的意义

Frontiers in Neuroscience
IF3.2
2025-10-240
OAAI
Lanboling Guo†; Jessica R. Gaunt†; Calvin Chee Hoe Cheah; Albert I. Chen; Stephanie Claudine; Gavin S. Dawe; Eyleen Lay Keow Goh; Sok-Hong Kho; Pawan Kumar; Grace G. Y. Lim; Kah Leong Lim; Yun-An Lim; Takaomi C. Saido; Takashi Saito; Hiroki Sasaguri; Judy C. G. Sng; Yee Jie Yeap; Alaric K. K. Yip; Norliyana Zainolabidin; Toh Hean Ch’ng‡; George J. Augustine‡

研究方向

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T
Takashi Saito
H 指数:70论文数:541被引数:1.7万
N
Nobuhisa Iwata
H 指数:56论文数:212被引数:1.6万
H
Hiroki Sasaguri
H 指数:23论文数:99被引数:3,521
M
Makoto Higuchi
H 指数:73论文数:695被引数:2.0万
J
Jiro Takano
H 指数:22论文数:65被引数:3,497
Y
Yukio Matsuba
H 指数:16论文数:64被引数:3,491
P
Per Nilsson
H 指数:34论文数:140被引数:5,723
B
Bart De Strooper
H 指数:142论文数:689被引数:7.7万
N
Naoto Watamura
H 指数:14论文数:44被引数:676
S
Shoko Hashimoto
H 指数:17论文数:53被引数:2,263