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Integrated miRNA-mRNA Analysis Reveals Obesity-Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes 整合miRNA-mRNA分析揭示有无2型糖尿病的人类内脏脂肪组织中肥胖驱动的调控网络 Villa-Fernandez, Elsa; Garcia, Ana Victoria; Gallardo-Nuell, Laura; Garcia-Villarino, Miguel; Fernandez-Garcia, Judit; Martin Alonso, Aldara; Lozano-Aida, Claudia; Suarez Gutierrez, Lorena; Pujante, Pedro; Ares, Jessica; Gonzalez-Vidal, Tomas; Rodriguez Uria, Raquel; Sanz Navarro, Sandra; Moreno Gijon, Maria; Sanz Alvarez, Lourdes Maria; Turienzo Santos, Estrella Olga; Fernandez-Real, Jose Manuel; Fernandez Fraga, Mario; Delgado, Elias; Lambert, Carmen 分享 收藏
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Advancing Personalized Medicine in Alzheimer's Disease: Liquid Biopsy Epigenomics Unveil APOE ε4-Linked Methylation Signatures 推进阿尔茨海默病个性化医学：液体活检表观基因组学揭示APOE ε4相关甲基化特征 Macias, Monica; Alba-Linares, Juan Jose; Acha, Blanca; Blanco-Luquin, Idoia; Fernandez, Agustin F.; Alvarez-Jimenez, Johana; Urdanoz-Casado, Amaya; Roldan, Miren; Robles, Maitane; Cabezon-Arteta, Eneko; Alcolea, Daniel; de Gordoa, Javier Sanchez Ruiz; Corroza, Jon; Cabello, Carolina; Erro, Maria Elena; Jerico, Ivonne; Fraga, Mario F.; Mendioroz, Maite 分享 收藏
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The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis lipopolysaccharide-TLR4轴调节肝谷氨酰胺酶1表达，促进肝氨积聚，因为脂肪性肝病进展为脂肪性肝炎 Mercado-Gomez, Maria; Goikoetxea-Usandizaga, Naroa; Kerbert, Annarein J. C.; Gracianteparaluceta, Leire Uraga; Serrano-Macia, Marina; Lachiondo-Ortega, Sofia; Rodriguez-Agudo, Ruben; Gil-Pitarch, Claudia; Simon, Jorge; Gonzalez-Recio, Irene; Fondevila, Marcos F.; Santamarina-Ojeda, Pablo; Fraga, Mario F.; Nogueiras, Ruben; de las Heras, Javier; Jalan, Rajiv; Martinez-Chantar, Maria Luz; Delgado, Teresa C. 分享 收藏
A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment 衰老海马的多体图谱揭示了响应环境富集的分子变化 Perez, Raul F.; Tezanos, Patricia; Penarroya, Alfonso; Gonzalez-Ramon, Alejandro; Urdinguio, Rocio G.; Gancedo-Verdejo, Javier; Tejedor, Juan Ramon; Santamarina-Ojeda, Pablo; Alba-Linares, Juan Jose; Sainz-Ledo, Lidia; Roberti, Annalisa; Lopez, Virginia; Mangas, Cristina; Moro, Maria; Reyes, Elisa Cintado; Martinez, Pablo Muela; Rodriguez-Santamaria, Mar; Ortea, Ignacio; Iglesias-Rey, Ramon; Castilla-Silgado, Juan; Tomas-Zapico, Cristina; Iglesias-Gutierrez, Eduardo; Fernandez-Garcia, Benjamin; Sanchez-Mut, Jose Vicente; Trejo, Jose Luis; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas Cubiella, Tamara; Celada, Lucia; San-Juan-Guardado, Jaime; Rodriguez-Aguilar, Raul; Suarez-Priede, Alvaro; Poch, Maria; Dominguez, Francisco; Fernandez-Vega, Ivan; Montero-Pavon, Pedro; Fraga, Mario F.; Nakatani, Yoichiro; Takata, So; Yachida, Shinichi; Valdes, Nuria; Chiara, Maria-Dolores 分享 收藏
Novel 14q32.2 paternal deletion encompassing the whole DLK1 gene associated with Temple syndrome Baena, Neus; Monk, David; Aguilera, Cinthia; Fraga, Mario F.; Fernandez, Agustin F.; Gabau, Elisabeth; Corripio, Raquel; Capdevila, Nuria; Trujillo, Juan Pablo; Ruiz, Anna; Guitart, Miriam 分享 收藏
A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma Rey, Veronica; Tornin, Juan; Alba-Linares, Juan Jose; Robledo, Cristina; Murillo, Dzohara; Rodriguez, Aida; Gallego, Borja; Huergo, Carmen; Viera, Cristina; Brana, Alejandro; Astudillo, Aurora; Heymann, Dominique; Szuhai, Karoly; Bovee, Judith V. M. G.; Fernandez, Agustin F.; Fraga, Mario F.; Alonso, Javier; Rodriguez, Rene 分享 收藏
A FokI-driven signal amplification platform for the simultaneous detection of multiple viral RNA pathogens Tejedor, Juan R.; Roberti, Annalisa; Mangas, Cristina; Alvarez-Arguelles, Marta E.; Rojo-Alba, Susana; Boga, Jose A.; Fernandez, Agustin F.; Melon, Santiago; Rodriguez, Mercedes; Fraga, Mario F. 分享 收藏
ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer Fernandez-De-Los-Reyes, Irene; Gomez-Dorronsoro, Marisa; Monreal-Santesteban, Inaki; Fernandez-Fernandez, Agustin; Fraga, Mario; Azcue, Pablo; Alonso, Laura; Fernandez-Marlasca, Beatriz; Suarez, Javier; Cordoba-Iturriagagoitia, Alicia; Guerrero-Setas, David 分享 收藏
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CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer CRISPR/dCAS9-mediated DNA去甲基化筛选鉴定结直肠癌的功能性表观遗传决定因素 Tejedor, Juan Ramon; Penarroya, Alfonso; Gancedo-Verdejo, Javier; Santamarina-Ojeda, Pablo; Perez, Raul F.; Lopez-Tamargo, Sara; Diez-Borge, Ana; Alba-Linares, Juan J.; Gonzalez-del-Rey, Nerea; Urdinguio, Rocio G.; Mangas, Cristina; Roberti, Annalisa; Lopez, Virginia; Morales-Ruiz, Teresa; Ariza, Rafael R.; Roldan-Arjona, Teresa; Meijon, Monica; Valledor, Luis; Canal, Maria Jesus; Fernandez-Martinez, Daniel; Fernandez-Hevia, Maria; Jimenez-Fonseca, Paula; Garcia-Florez, Luis J.; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
DPPA3-HIF1a axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype Cuesta-Borras, Estefania; Salvans, Candida; Arques, Oriol; Chicote, Irene; Ramirez, Lorena; Cabellos, Laia; Martinez-Quintanilla, Jordi; Mur-Espinosa, Alex; Garcia-Alvarez, Alejandro; Hernando, Jorge; Tejedor, Juan Ramon; Mirallas, Oriol; Elez, Elena; Fraga, Mario F.; Tabernero, Josep; Nuciforo, Paolo; Capdevila, Jaume; Palmer, Hector G.; Puig, Isabel 分享 收藏
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Circulating miRNA expression in long-standing type 1 diabetes mellitus Morales-Sanchez, Paula; Lambert, Carmen; Ares-Blanco, Jessica; Suarez-Gutierrez, Lorena; Villa-Fernandez, Elsa; Garcia, Ana Victoria; Garcia-Villarino, Miguel; Tejedor, Juan Ramon; Fraga, Mario F.; Torre, Edelmiro Menendez; Pujante, Pedro; Delgado, Elias 分享 收藏
Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis Roberti, Annalisa; Tejedor, Juan Ramon; Diaz-Moreno, Irene; Lopez, Virginia; Santamarina-Ojeda, Pablo; Perez, Raul F.; Urdinguio, Rocio G.; Concellon, Carmen; Martinez-Chantar, Maria Luz; Fernandez-Morera, Juan Luis; Diaz-Quintana, Antonio; del Amo, Vicente; Fernandez, Agustin F.; Fraga, Mario F. 分享 收藏
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